(Q43177447)

English

Evidence of oxidative stress and associated DNA damage, increased proliferative drive, and altered gene expression in rat liver produced by the cholangiocarcinogenic agent furan

scientific article published on 2 February 2010

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scholarly article

1 reference

Europe PubMed Central

15 November 2017

Evidence of oxidative stress and associated DNA damage, increased proliferative drive, and altered gene expression in rat liver produced by the cholangiocarcinogenic agent furan (English)

1 reference

Europe PubMed Central

15 November 2017

0 references

author name string

K C Hickling

1

1 reference

Europe PubMed Central

15 November 2017

J M Hitchcock

2

1 reference

Europe PubMed Central

15 November 2017

V Oreffo

3

1 reference

Europe PubMed Central

15 November 2017

A Mally

4

1 reference

Europe PubMed Central

15 November 2017

T G Hammond

5

1 reference

Europe PubMed Central

15 November 2017

J G Evans

6

1 reference

Europe PubMed Central

15 November 2017

J K Chipman

7

1 reference

Europe PubMed Central

15 November 2017

language of work or name

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publication date

2 February 2010

1 reference

Europe PubMed Central

15 November 2017

Toxicologic Pathology

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Europe PubMed Central

15 November 2017

38

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Europe PubMed Central

15 November 2017

2

1 reference

Europe PubMed Central

15 November 2017

230-243

1 reference

Europe PubMed Central

15 November 2017

p53 but not bcl-2 is expressed by most cholangiocarcinomas: a study of 28 cases

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

Adaptative bile duct proliferative response in experimental bile duct ischemia.

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

Characterization of nucleoside adducts of cis-2-butene-1,4-dial, a reactive metabolite of furan

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

The formation of substituted 1,N6-etheno-2'-deoxyadenosine and 1,N2-etheno-2'-deoxyguanosine adducts by cis-2-butene-1,4-dial, a reactive metabolite of furan

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

Progenitor cells of the biliary epithelial cell lineage

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

Furan-induced liver cell proliferation and apoptosis in female B6C3F1 mice.

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

V79-hCYP2E1-hSULT1A1, a cell line for the sensitive detection of genotoxic effects induced by carbohydrate pyrolysis products and other food-borne chemicals.

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

In situ detection of fragmented DNA (TUNEL assay) fails to discriminate among apoptosis, necrosis, and autolytic cell death: a cautionary note

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

Fine-tuning furan toxicity: fast and quantitative DNA interchain cross-link formation upon selective oxidation of a furan containing oligonucleotide.

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

Integration of clinical and gene expression endpoints to explore furan-mediated hepatotoxicity

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

Induction and progression of cholangiofibrosis in rat liver injured by oral administration of furan

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

Gene expression profiling reveals multiple toxicity endpoints induced by hepatotoxicants

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

K-ras codon 12 and p53 mutations in biopsy specimens and bile from biliary tract cancers.

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

Tests for genotoxicity and mutagenicity of furan and its metabolite cis-2-butene-1,4-dial in L5178Y tk+/- mouse lymphoma cells

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

Changing international trends in mortality rates for liver, biliary and pancreatic tumours

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

Unique epithelial cell production of hepatocyte growth factor/scatter factor by putative precancerous intestinal metaplasias and associated "intestinal-type" biliary cancer chemically induced in rat liver

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

Genotoxicity of 1,3-dithiane and 1,4-dithiane in the CHO/SCE assay and the Salmonella/microsomal test.

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

Furans in foods

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

Non-genotoxic carcinogens: early effects on gap junctions, cell proliferation and apoptosis in the rat.

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

Transforming growth factor-beta differentially regulates oval cell and hepatocyte proliferation

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

Regulating the onset of mitosis

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

A role of cyclin G in the process of apoptosis

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

The myc oncogene: MarvelouslY Complex

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

2-acetylaminofluorene dose-dependent differentiation of rat oval cells into hepatocytes: confocal and electron microscopic studies

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

Origin and structural evolution of the early proliferating oval cells in rat liver

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

Origin and mechanistic pathways of formation of the parent furan--a food toxicant

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

A reactive metabolite of furan, cis-2-butene-1,4-dial, is mutagenic in the Ames assay.

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

Overexpression of C-NEU and C-MET during rat liver cholangiocarcinogenesis: A link between biliary intestinal metaplasia and mucin-producing cholangiocarcinoma

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

Expression of an intestine-specific transcription factor (CDX1) in intestinal metaplasia and in subsequently developed intestinal type of cholangiocarcinoma in rat liver

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

Differential gene expression in drug metabolism and toxicology: practicalities, problems and potential

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

Thymosin beta-10 gene overexpression is a general event in human carcinogenesis

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

Identification of novel molecules and pathogenic pathways in primary biliary cirrhosis: cDNA array analysis of intrahepatic differential gene expression

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

AP-1 in cell proliferation and survival

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

CyclinG contributes to G2/M arrest of cells in response to DNA damage

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

Biliary proliferation and adaptation in furan-induced rat liver injury and carcinogenesis

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

Immortalizing hepatocytes with truncated MET: a little bit of gene goes a long way.

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

Characterization of rat hyperplastic bile ductular epithelial cells in culture andin vivo

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

Biliary cancer growth factor pathways, cyclo-oxygenase-2 and potential therapeutic strategies

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

Frequency of p16(INK4A) alterations and K-ras mutations in intrahepatic cholangiocarcinoma of the liver

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

Increase in mortality rates from intrahepatic cholangiocarcinoma in England and Wales 1968-1998.

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

Human ING1 proteins differentially regulate histone acetylation

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

Evaluation of genotoxicity, pathological lesions, and cell proliferation in livers of rats and mice treated with furan

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

Expression ofmyc, fos, and ha-ras in the livers of furan-treated f344 rats and b6c3f1 mice

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

Myc represses the growth arrest gene gadd45

1 reference

https://api.crossref.org/works/10.1177%2F0192623309357946

21 January 2018

Identifiers

10.1177/0192623309357946

1 reference

Europe PubMed Central

15 November 2017

1 reference

Europe PubMed Central

15 November 2017

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