(Q43187673)

English

Pharmacokinetics, pharmacodynamics, tolerability and safety of single ascending doses of ticagrelor, a reversibly binding oral P2Y(12) receptor antagonist, in healthy subjects

scientific article published on 21 January 2010

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

15 November 2017

Pharmacokinetics, pharmacodynamics, tolerability and safety of single ascending doses of ticagrelor, a reversibly binding oral P2Y(12) receptor antagonist, in healthy subjects (English)

1 reference

Europe PubMed Central

PubMed publication ID

15 November 2017

pharmacokinetics

1 reference

based on heuristic

inferred from title

pharmacodynamics

1 reference

based on heuristic

inferred from title

author name string

Renli Teng

1

1 reference

Europe PubMed Central

PubMed publication ID

15 November 2017

Kathleen Butler

2

1 reference

Europe PubMed Central

PubMed publication ID

15 November 2017

publication date

21 January 2010

1 reference

Europe PubMed Central

PubMed publication ID

15 November 2017

European Journal of Clinical Pharmacology

1 reference

Europe PubMed Central

PubMed publication ID

15 November 2017

66

1 reference

Europe PubMed Central

PubMed publication ID

15 November 2017

5

1 reference

Europe PubMed Central

PubMed publication ID

15 November 2017

487-496

1 reference

Europe PubMed Central

PubMed publication ID

15 November 2017

https://scigraph.springernature.com/pub.10.1007/s00228-009-0778-5

0 references

ACC/AHA 2007 guidelines for the management of patients with unstable angina/non ST-elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Rev

1 reference

https://pubmed.ncbi.nlm.nih.gov/20091161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Platelet function testing: state of the art

1 reference

https://pubmed.ncbi.nlm.nih.gov/20091161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Safety, tolerability, and initial efficacy of AZD6140, the first reversible oral adenosine diphosphate receptor antagonist, compared with clopidogrel, in patients with non-ST-segment elevation acute coronary syndrome: primary results of the DISPERSE

1 reference

https://pubmed.ncbi.nlm.nih.gov/20091161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clopidogrel resistance is associated with increased risk of recurrent atherothrombotic events in patients with acute myocardial infarction

1 reference

https://pubmed.ncbi.nlm.nih.gov/20091161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ticagrelor: the first reversibly binding oral P2Y12 receptor antagonist

1 reference

https://pubmed.ncbi.nlm.nih.gov/20091161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variability in individual responsiveness to clopidogrel: clinical implications, management, and future perspectives

1 reference

https://pubmed.ncbi.nlm.nih.gov/20091161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variable therapeutic effectiveness of clopidogrel in acute coronary syndromes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20091161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Repeated-dose pharmacodynamics of clopidogrel in healthy subjects

1 reference

https://pubmed.ncbi.nlm.nih.gov/20091161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Guidelines for the diagnosis and treatment of non-ST-segment elevation acute coronary syndromes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20091161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A comparison of prasugrel and clopidogrel loading doses on platelet function: magnitude of platelet inhibition is related to active metabolite formation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20091161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20091161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prasugrel achieves greater inhibition of platelet aggregation and a lower rate of non-responders compared with clopidogrel in aspirin-treated patients with stable coronary artery disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20091161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacodynamics, pharmacokinetics, and safety of the oral reversible P2Y12 antagonist AZD6140 with aspirin in patients with atherosclerosis: a double-blind comparison to clopidogrel with aspirin

1 reference

https://pubmed.ncbi.nlm.nih.gov/20091161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Early and sustained dual oral antiplatelet therapy following percutaneous coronary intervention: a randomized controlled trial

1 reference

https://pubmed.ncbi.nlm.nih.gov/20091161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Increased risk in patients with high platelet aggregation receiving chronic clopidogrel therapy undergoing percutaneous coronary intervention: is the current antiplatelet therapy adequate?

1 reference

https://pubmed.ncbi.nlm.nih.gov/20091161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A quick method for screening platelet dysfunctions using the whole blood lumi-aggregometer

1 reference

https://pubmed.ncbi.nlm.nih.gov/20091161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

From ATP to AZD6140: the discovery of an orally active reversible P2Y12 receptor antagonist for the prevention of thrombosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20091161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ticagrelor versus clopidogrel in patients with acute coronary syndromes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20091161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of clopidogrel pretreatment before percutaneous coronary intervention in patients with ST-elevation myocardial infarction treated with fibrinolytics: the PCI-CLARITY study

1 reference

https://pubmed.ncbi.nlm.nih.gov/20091161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

P2 receptors, platelet function and pharmacological implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/20091161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low response to clopidogrel is associated with cardiovascular outcome after coronary stent implantation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20091161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Comparison of ticagrelor, the first reversible oral P2Y(12) receptor antagonist, with clopidogrel in patients with acute coronary syndromes: Rationale, design, and baseline characteristics of the PLATelet inhibition and patient Outcomes (PLATO) tria

1 reference

https://pubmed.ncbi.nlm.nih.gov/20091161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Durability of platelet inhibition by clopidogrel

1 reference

https://pubmed.ncbi.nlm.nih.gov/20091161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Resistance to antiplatelet drugs: current status and future research

1 reference

https://pubmed.ncbi.nlm.nih.gov/20091161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Impact of platelet reactivity after clopidogrel administration on drug-eluting stent thrombosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20091161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Matching the evaluation of the clinical efficacy of clopidogrel to platelet function tests relevant to the biological properties of the drug

1 reference

https://pubmed.ncbi.nlm.nih.gov/20091161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of platelet aggregation by AZD6140, a reversible oral P2Y12 receptor antagonist, compared with clopidogrel in patients with acute coronary syndromes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20091161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The electronic aggregometer: a novel device for assessing platelet behavior in blood

1 reference

https://pubmed.ncbi.nlm.nih.gov/20091161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20091161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1 reference

https://pubmed.ncbi.nlm.nih.gov/20091161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Preclinical and clinical studies with selective reversible direct P2Y12 antagonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/20091161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Prasugrel versus clopidogrel in patients with acute coronary syndromes

1 reference

https://pubmed.ncbi.nlm.nih.gov/20091161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Variability in platelet responsiveness to clopidogrel among 544 individuals.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20091161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Drug insight: Clopidogrel nonresponsiveness

1 reference

https://pubmed.ncbi.nlm.nih.gov/20091161

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1007/S00228-009-0778-5

1 reference

Europe PubMed Central

PubMed publication ID

15 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

15 November 2017

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q43187673&oldid=2143926295"