(Q43188167)

English

The type I interferon-alpha mediates a more severe neurological disease in the absence of the canonical signaling molecule interferon regulatory factor 9.

scientific article published in January 2010

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20089923%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

The type I interferon-alpha mediates a more severe neurological disease in the absence of the canonical signaling molecule interferon regulatory factor 9 (English)

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20089923%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

author name string

Markus J Hofer

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20089923%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Wen Li

2

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20089923%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Sue Ling Lim

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20089923%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Iain L Campbell

4

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20089923%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

language of work or name

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publication date

1 January 2010

1 reference

Europe PubMed Central

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17 January 2020

Journal of Neuroscience

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20089923%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

30

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20089923%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20089923%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1149-1157

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20089923%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Chemokines and the inflammatory response to viral infection in the central nervous system with a focus on lymphocytic choriomeningitis virus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human cytomegalovirus inhibits IFN-alpha-stimulated antiviral and immunoregulatory responses by blocking multiple levels of IFN-alpha signal transduction.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structural and functional neuropathology in transgenic mice with CNS expression of IFN-alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferons as a paradigm for cytokine signal transduction

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IFN-gamma shapes immune invasion of the central nervous system via regulation of chemokines.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immune response in Stat2 knockout mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of gamma interferon in antimicrobial immunity

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferon-independent, human immunodeficiency virus type 1 gp120-mediated induction of CXCL10/IP-10 gene expression by astrocytes in vivo and in vitro

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of signal transducer and activator of transcription and suppressor of cytokine-signaling gene expression in the brain of mice with astrocyte-targeted production of interleukin-12 or experimental autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Leukocyte infiltration, but not neurodegeneration, in the CNS of transgenic mice with astrocyte production of the CXC chemokine ligand 10.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Critical role for STAT4 activation by type 1 interferons in the interferon-gamma response to viral infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

STAT1 deficiency unexpectedly and markedly exacerbates the pathophysiological actions of IFN-alpha in the central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cree encephalitis is allelic with Aicardi-Goutiéres syndrome: implications for the pathogenesis of disorders of interferon alpha metabolism

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

STAT1-dependent innate immunity to a Norwalk-like virus

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

STAT protein interference and suppression of cytokine signal transduction by measles virus V protein

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Dysregulated Sonic hedgehog signaling and medulloblastoma consequent to IFN-alpha-stimulated STAT2-independent production of IFN-gamma in the brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Innate STAT1-dependent genomic response of neurons to the antiviral cytokine alpha interferon

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Complex modulation of cell type-specific signaling in response to type I interferons

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Type I interferon response in the central nervous system

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stat2-dependent regulation of MHC class II expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Review and meta-analysis of the epidemiology of congenital cytomegalovirus (CMV) infection

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Clinical and molecular phenotype of Aicardi-Goutieres syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Isolation and characterization of a new mutant human cell line unresponsive to alpha and beta interferons

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reovirus mu2 protein inhibits interferon signaling through a novel mechanism involving nuclear accumulation of interferon regulatory factor 9.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unaltered neurological disease and mortality in CXCR3-deficient mice infected intracranially with lymphocytic choriomeningitis virus-Armstrong

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferon-gamma prevents death of bystander neurons during CD8 T cell responses in the brain

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferon gamma in acute and subacute encephalitis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intrathecal synthesis of interferon-alpha in infants with progressive familial encephalopathy

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Encephalitis among Cree children in northern Quebec

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intrathecal synthesis of different alpha-interferons in patients with various neurological diseases.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A progressive familial encephalopathy in infancy with calcifications of the basal ganglia and chronic cerebrospinal fluid lymphocytosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cell culture systems to study glial transformation

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interferon-induced antiviral actions and their regulation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A single phosphotyrosine residue of Stat91 required for gene activation by interferon-gamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A developmental analysis of oligodendroglial integrins in primary cells: changes in alpha v-associated beta subunits during differentiation.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification and characterization of an interferon (IFN)-stimulated response element-IFN-stimulated gene factor 3-independent signaling pathway for IFN-alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Patterns of cytokine gene expression by CD4+ T cells from young and old mice.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ectopic expression of gamma interferon in the eyes of transgenic mice induces ocular pathology and MHC class II gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transgenic mice expressing IFN-gamma in the retina develop inflammation of the eye and photoreceptor loss

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Viral infections of the CNS in children: imaging features

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immune response in mice that lack the interferon-gamma receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE).

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeted disruption of the mouse Stat1 gene results in compromised innate immunity to viral disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Formation of STAT1-STAT2 heterodimers and their role in the activation of IRF-1 gene transcription by interferon-alpha

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of adenovirus E1A protein on interferon-signaling

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

IFN-gamma plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Essential and non-redundant roles of p48 (ISGF3 gamma) and IRF-1 in both type I and type II interferon responses, as revealed by gene targeting studies

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

GAS elements: a few nucleotides with a major impact on cytokine-induced gene expression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cellular responses to interferon-gamma

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemokine gene expression in the brains of mice with lymphocytic choriomeningitis

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

How cells respond to interferons

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Transgenic expression of IFN-alpha in the central nervous system of mice protects against lethal neurotropic viral infection but induces inflammation and neurodegeneration.

1 reference

https://pubmed.ncbi.nlm.nih.gov/20089923

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.3711-09.2010

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20089923%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20089923%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20089923%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

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