(Q43194838)

English

The adaptor molecule signaling lymphocytic activation molecule-associated protein (SAP) regulates IFN-gamma and IL-4 production in V alpha 14 transgenic NKT cells via effects on GATA-3 and T-bet expression

scientific article published in February 2009

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scholarly article

1 reference

Europe PubMed Central

15 November 2017

The adaptor molecule signaling lymphocytic activation molecule-associated protein (SAP) regulates IFN-gamma and IL-4 production in V alpha 14 transgenic NKT cells via effects on GATA-3 and T-bet expression (English)

1 reference

Europe PubMed Central

15 November 2017

author name string

Osman Cen

1

1 reference

Europe PubMed Central

15 November 2017

Aki Ueda

2

1 reference

Europe PubMed Central

15 November 2017

Laura Guzman

3

1 reference

Europe PubMed Central

15 November 2017

Jimmy Jain

4

1 reference

Europe PubMed Central

15 November 2017

Hamid Bassiri

5

1 reference

Europe PubMed Central

15 November 2017

Kim E Nichols

6

1 reference

Europe PubMed Central

15 November 2017

Paul L Stein

7

1 reference

Europe PubMed Central

15 November 2017

language of work or name

0 references

publication date

1 February 2009

1 reference

Europe PubMed Central

15 November 2017

Journal of Immunology

1 reference

Europe PubMed Central

15 November 2017

182

1 reference

Europe PubMed Central

15 November 2017

3

1 reference

Europe PubMed Central

15 November 2017

1370-1378

1 reference

Europe PubMed Central

15 November 2017

Differential requirement for the SAP-Fyn interaction during NK T cell development and function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

25 May 2018

The SLAM and SAP gene families control innate and adaptive immune responses.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

25 May 2018

Requirements for selection of conventional and innate T lymphocyte lineages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

25 May 2018

The SLAM-associated protein signaling pathway is required for development of CD4+ T cells selected by homotypic thymocyte interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

25 May 2018

Homotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

25 May 2018

Thymic selection pathway regulates the effector function of CD4 T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

25 May 2018

NKT cells: T lymphocytes with innate effector functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

25 May 2018

Invariant NKT cells sustain specific B cell responses and memory

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

25 May 2018

Regulation of cellular and humoral immune responses by the SLAM and SAP families of molecules.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

25 May 2018

GATA-3 regulates the development and function of invariant NKT cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

25 May 2018

The X-linked lymphoproliferative disease gene product SAP associates with PAK-interacting exchange factor and participates in T cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

25 May 2018

Mechanisms imposing the Vbeta bias of Valpha14 natural killer T cells and consequences for microbial glycolipid recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

25 May 2018

Selective generation of functional somatically mutated IgM+CD27+, but not Ig isotype-switched, memory B cells in X-linked lymphoproliferative disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

25 May 2018

Developmental program of mouse Valpha14i NKT cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

25 May 2018

Defective NKT cell development in mice and humans lacking the adapter SAP, the X-linked lymphoproliferative syndrome gene product

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

25 May 2018

Molecular and cellular pathogenesis of X-linked lymphoproliferative disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

25 May 2018

The cell surface receptor SLAM controls T cell and macrophage functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

25 May 2018

SAP increases FynT kinase activity and is required for phosphorylation of SLAM and Ly9.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

25 May 2018

Constitutive Cytokine mRNAs Mark Natural Killer (NK) and NK T Cells Poised for Rapid Effector Function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

25 May 2018

NIK-dependent RelB activation defines a unique signaling pathway for the development of V alpha 14i NKT cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

25 May 2018

BATF transgenic mice reveal a role for activator protein-1 in NKT cell development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

25 May 2018

SAP is required for generating long-term humoral immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

25 May 2018

Gene silencing quantitatively controls the function of a developmental trans-activator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

25 May 2018

A natural killer T (NKT) cell developmental pathway iInvolving a thymus-dependent NK1.1(-)CD4(+) CD1d-dependent precursor stage

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

25 May 2018

Regulation of SLAM-mediated signal transduction by SAP, the X-linked lymphoproliferative gene product

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

25 May 2018

GATA-3 induces T helper cell type 2 (Th2) cytokine expression and chromatin remodeling in committed Th1 cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

25 May 2018

NK1.1+ T cells in the liver arise in the thymus and are selected by interactions with class I molecules on CD4+CD8+ cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

25 May 2018

The Src family tyrosine kinase Fyn regulates natural killer T cell development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

25 May 2018

The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

25 May 2018

Increased interleukin 4 and immunoglobulin E production in transgenic mice overexpressing NK1 T cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

25 May 2018

Regulation of AP-1 and NFAT transcription factors during thymic selection of T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

25 May 2018

Bcl-XL and Bcl-2 repress a common pathway of cell death

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

25 May 2018

Defective T cell receptor signaling in mice lacking the thymic isoform of p59fyn

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

25 May 2018

SAP regulation of follicular helper CD4 T cell development and humoral immunity is independent of SLAM and Fyn kinase.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

15 August 2018

Restoration of NK T cell development in fyn-mutant mice by a TCR reveals a requirement for Fyn during early NK T cell ontogeny

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

15 August 2018

T-bet regulates the terminal maturation and homeostasis of NK and Valpha14i NKT cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

15 August 2018

NF-kappa B controls cell fate specification, survival, and molecular differentiation of immunoregulatory natural T lymphocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

15 August 2018

Differential requirement for Rel/nuclear factor kappa B family members in natural killer T cell development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

15 August 2018

NK T cell precursors exhibit differential cytokine regulation and require Itk for efficient maturation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

15 August 2018

Sustained NFAT signaling promotes a Th1-like pattern of gene expression in primary murine CD4+ T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

15 August 2018

Early TCR alpha beta expression promotes maturation of T cells expressing Fc epsilon RI gamma containing TCR/CD3 complexes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

15 August 2018

Cutting edge: NKT cell development is selectively impaired in Fyn- deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2630172

15 August 2018

Role for IL-15/IL-15 receptor beta-chain in natural killer 1.1+ T cell receptor-alpha beta+ cell development

1 reference

https://pubmed.ncbi.nlm.nih.gov/19155483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A TCR alpha chain transgene induces maturation of CD4- CD8- alpha beta+ T cells from gamma delta T cell precursors

1 reference

https://pubmed.ncbi.nlm.nih.gov/19155483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

SAP regulates T(H)2 differentiation and PKC-theta-mediated activation of NF-kappaB1

1 reference

https://pubmed.ncbi.nlm.nih.gov/19155483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of NKT cell development by SAP, the protein defective in XLP

1 reference

https://pubmed.ncbi.nlm.nih.gov/19155483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting Edge: Signaling Lymphocytic Activation Molecule-Associated Protein Controls NKT Cell Functions

1 reference

https://pubmed.ncbi.nlm.nih.gov/19155483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of Th2 cytokine expression in NKT cells: unconventional use of Stat6, GATA-3, and NFAT2

1 reference

https://pubmed.ncbi.nlm.nih.gov/19155483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Slamf1, the NKT cell control gene Nkt1

1 reference

https://pubmed.ncbi.nlm.nih.gov/19155483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A thymic precursor to the NK T cell lineage

1 reference

https://pubmed.ncbi.nlm.nih.gov/19155483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Enforced expression of Bcl-2 restores the number of NK cells, but does not rescue the impaired development of NKT cells or intraepithelial lymphocytes, in IL-2/IL-15 receptor beta-chain-deficient mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/19155483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

bcl-2 transgene inhibits T cell death and perturbs thymic self-censorship

1 reference

https://pubmed.ncbi.nlm.nih.gov/19155483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

pp59fyn mutant mice display differential signaling in thymocytes and peripheral T cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19155483

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.4049/JIMMUNOL.182.3.1370

1 reference

Europe PubMed Central

15 November 2017

1 reference

Europe PubMed Central

15 November 2017

1 reference

Europe PubMed Central

15 November 2017

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