(Q43202783)

16 November 2017

title

Preclinical characterization of BRL 44408: antidepressant- and analgesic-like activity through selective alpha2A-adrenoceptor antagonism (English)

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16 November 2017

Jason M Dwyer

1

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16 November 2017

Brian J Platt

2

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16 November 2017

Stacey J Sukoff Rizzo

3

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16 November 2017

Claudine M Pulicicchio

4

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16 November 2017

Caitlin Wantuch

5

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16 November 2017

Mei-Yi Zhang

6

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16 November 2017

Terri Cummons

7

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16 November 2017

Liza Leventhal

8

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16 November 2017

Corey N Bender

9

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16 November 2017

Jean Zhang

10

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16 November 2017

Dianne Kowal

11

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16 November 2017

Shendi Lu

12

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16 November 2017

S Johannes R Rajarao

13

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16 November 2017

Deborah L Smith

14

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16 November 2017

Adam D Shilling

15

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16 November 2017

Jianyao Wang

16

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16 November 2017

John Butera

17

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16 November 2017

Lynn Resnick

18

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16 November 2017

Sharon Rosenzweig-Lipson

19

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16 November 2017

Lee E Schechter

20

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16 November 2017

Chad E Beyer

21

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16 November 2017

publication date

5 January 2010

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The International Journal of Neuropsychopharmacology

16 November 2017

published in

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16 November 2017

volume

13

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16 November 2017

issue

9

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16 November 2017

page(s)

1193-1205

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Differential behavioral effects of the antidepressants reboxetine, fluoxetine, and moclobemide in a modified forced swim test following chronic treatment

16 November 2017

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Alpha-adrenoceptor subtypes

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7 January 2021

Effects of acute and subchronic administration of dexefaroxan, an alpha(2)-adrenoceptor antagonist, on memory performance in young adult and aged rodents

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Addition of the alpha2-antagonist yohimbine to fluoxetine: effects on rate of antidepressant response

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7 January 2021

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

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7 January 2021

Genetic alteration of alpha 2C-adrenoceptor expression in mice: influence on locomotor, hypothermic, and neurochemical effects of dexmedetomidine, a subtype-nonselective alpha 2-adrenoceptor agonist.

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7 January 2021

Brain metabolic changes in major depressive disorder from pre- to post-treatment with paroxetine

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Antidepressant-like effects of the novel, selective, 5-HT2C receptor agonist WAY-163909 in rodents

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Prefrontal-subcortical and limbic circuit mediation of major depressive disorder

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The alpha2-adrenoceptor antagonist dexefaroxan enhances hippocampal neurogenesis by increasing the survival and differentiation of new granule cells

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7 January 2021

Comparison of the effects of antidepressants on norepinephrine and serotonin concentrations in the rat frontal cortex: an in-vivo microdialysis study

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7 January 2021

Synthesis of a selective alpha-2A adrenoceptor antagonist, BRL 48962, and its characterization at cloned human alpha-adrenoceptors

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7 January 2021

Adrenergic pharmacology and cognition: focus on the prefrontal cortex

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7 January 2021

Depression and pain comorbidity: a literature review

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7 January 2021

The release of noradrenaline in the locus coeruleus and prefrontal cortex studied with dual-probe microdialysis

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7 January 2021

Human brain mechanisms of pain perception and regulation in health and disease.

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Citalopram elicits a discriminative stimulus in rats at a dose selectively increasing extracellular levels of serotonin vs. dopamine and noradrenaline.

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7 January 2021

Antidepressants and pain

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7 January 2021

The subtype-selective alpha 2-adrenoceptor antagonists BRL 44408 and ARC 239 also recognize 5-HT1A receptors in the rat brain.

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7 January 2021

A method for evaluating both non-narcotic and narcotic analgesics

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7 January 2021

Differential and synergistic effects of selective norepinephrine and serotonin reuptake inhibitors in rodent models of pain

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7 January 2021

α2-Adrenergic drug effects on brain monoamines, locomotion, and body temperature are largely abolished in mice lacking the α2A-adrenoceptor subtype

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7 January 2021

Cloning, sequencing, and expression of the gene coding for the human platelet alpha 2-adrenergic receptor

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7 January 2021

Subtype-specificity of the presynaptic alpha 2-adrenoceptors modulating hippocampal norepinephrine release in rat

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7 January 2021

Central administration of IGF-I and BDNF leads to long-lasting antidepressant-like effects

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7 January 2021

Acceleration of onset of action in schedule-induced polydipsia: combinations of SSRI and 5-HT1A and 5-HT1B receptor antagonists

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7 January 2021

Idazoxan preferentially increases dopamine output in the rat medial prefrontal cortex at the nerve terminal level.

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7 January 2021

Two functionally distinct alpha2-adrenergic receptors regulate sympathetic neurotransmission

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7 January 2021

Simultaneous quantification of serotonin, dopamine and noradrenaline levels in single frontal cortex dialysates of freely-moving rats reveals a complex pattern of reciprocal auto- and heteroreceptor-mediated control of release.

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7 January 2021

Alpha-adrenergic receptor (alpha(2 A )) is colocalized in basal forebrain cholinergic neurons: a light and electron microscopic double immunolabeling study

1 reference

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7 January 2021

Quantification and pharmacological characterization of dialysate levels of noradrenaline in the striatum of freely-moving rats: release from adrenergic terminals and modulation by alpha2-autoreceptors

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https://api.crossref.org/works/10.1017%2FS1461145709991088

7 January 2021

Genetic dissection of alpha2-adrenoceptor functions in adrenergic versus nonadrenergic cells

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https://api.crossref.org/works/10.1017%2FS1461145709991088

7 January 2021

Novel alpha 2-adrenoceptor antagonists show selectivity for alpha 2A- and alpha 2B-adrenoceptor subtypes

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https://api.crossref.org/works/10.1017%2FS1461145709991088

7 January 2021

Alpha-2 agonist-induced memory impairment is mediated by the alpha-2A-adrenoceptor subtype

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7 January 2021

Selective serotonin re-uptake inhibitors decrease schedule-induced polydipsia in rats: a potential model for obsessive compulsive disorder

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7 January 2021

DiPOA ([8-(3,3-diphenyl-propyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]dec-3-yl]-acetic acid), a novel, systemically available, and peripherally restricted Mu opioid agonist with antihyperalgesic activity: II. In vivo pharmacological characterization

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7 January 2021

Simultaneous increases of extracellular monoamines in microdialysates from hypothalamus of conscious rats by duloxetine, a dual serotonin and norepinephrine uptake inhibitor

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7 January 2021

In vivo microdialysis of noradrenaline overflow: effects of alpha-adrenoceptor agonists and antagonists measured by cumulative concentration-response curves

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7 January 2021

A note on a simple apparatus for detecting neurological deficit in rats and mice

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7 January 2021

Localization of alpha 2A- and alpha 2B-adrenergic receptor subtypes in brain.

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7 January 2021

Analgesic activity of tricyclic antidepressants

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7 January 2021

Effects of venlafaxine on extracellular concentrations of 5-HT and noradrenaline in the rat frontal cortex: augmentation via 5-HT1A receptor antagonism

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7 January 2021

alpha 2-Adrenergic receptors in human spinal cord: specific localized expression of mRNA encoding alpha 2-adrenergic receptor subtypes at four distinct levels

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7 January 2021

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7 January 2021

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Identifiers

DOI

1 reference

16 November 2017

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