(Q43248379)

English

Loss of MMP-2 disrupts skeletal and craniofacial development and results in decreased bone mineralization, joint erosion and defects in osteoblast and osteoclast growth

scientific article published on 30 March 2007

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

17 November 2017

Loss of MMP-2 disrupts skeletal and craniofacial development and results in decreased bone mineralization, joint erosion and defects in osteoblast and osteoclast growth (English)

1 reference

Europe PubMed Central

PMC publication ID

17 November 2017

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9

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17 November 2017

author name string

Rebecca A Mosig

1

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17 November 2017

Oonagh Dowling

2

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17 November 2017

Analisa DiFeo

3

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17 November 2017

Maria Celeste M Ramirez

4

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Europe PubMed Central

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17 November 2017

Ian C Parker

5

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17 November 2017

Etsuko Abe

6

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17 November 2017

Janane Diouri

7

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Europe PubMed Central

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17 November 2017

Aida Al Aqeel

8

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Europe PubMed Central

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17 November 2017

Samantha A Oblander

10

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Europe PubMed Central

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17 November 2017

Joseph Madri

11

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17 November 2017

Paolo Bianco

12

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17 November 2017

Suneel S Apte

13

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17 November 2017

Mone Zaidi

14

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17 November 2017

Stephen B Doty

15

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17 November 2017

Robert J Majeska

16

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Europe PubMed Central

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17 November 2017

Mitchell B Schaffler

17

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17 November 2017

John A Martignetti

18

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17 November 2017

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publication date

30 March 2007

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Europe PubMed Central

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17 November 2017

Human Molecular Genetics

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Europe PubMed Central

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17 November 2017

16

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9

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17 November 2017

1113-1123

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17 November 2017

A novel homozygous MMP2 mutation in a family with Winchester syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

Winchester syndrome caused by a homozygous mutation affecting the active site of matrix metalloproteinase 2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

Altered endochondral bone development in matrix metalloproteinase 13-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

Regulation of matrix biology by matrix metalloproteinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

Matrix metalloproteinase-2 cleavage of adrenomedullin produces a vasoconstrictor out of a vasodilator

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

Matrix metalloproteinases (MMPs) safeguard osteoblasts from apoptosis during transdifferentiation into osteocytes: MT1-MMP maintains osteocyte viability

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

MT1-MMP-dependent, apoptotic remodeling of unmineralized cartilage: a critical process in skeletal growth

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

Genetic disorders of the skeleton: a developmental approach

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

Extracellular matrix remodelling: the role of matrix metalloproteinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

Control of osteoblast function and regulation of bone mass

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

The genetic basis for skeletal diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

Matrix metalloproteinase-dependent activation of latent transforming growth factor-beta controls the conversion of osteoblasts into osteocytes by blocking osteoblast apoptosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

Reaching a genetic and molecular understanding of skeletal development

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

Endoneurial remodeling by TNFalph- and TNFalpha-releasing proteases. A spatial and temporal co-localization study in painful neuropathy

1 reference

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25 May 2018

A mutation in the LDL receptor-related protein 5 gene results in the autosomal dominant high-bone-mass trait

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

LDL receptor-related protein 5 (LRP5) affects bone accrual and eye development

1 reference

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25 May 2018

Matrix metalloproteinases: they're not just for matrix anymore!

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

Mutation of the matrix metalloproteinase 2 gene (MMP2) causes a multicentric osteolysis and arthritis syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

Matrix metalloproteinase 9 and vascular endothelial growth factor are essential for osteoclast recruitment into developing long bones

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

Inflammation dampened by gelatinase A cleavage of monocyte chemoattractant protein-3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

New form of idiopathic osteolysis: nodulosis, arthropathy and osteolysis (NAO) syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

Inactivating mutation of the mouse tissue inhibitor of metalloproteinases-2(Timp-2) gene alters proMMP-2 activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

Impaired endochondral ossification and angiogenesis in mice deficient in membrane-type matrix metalloproteinase I

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

The matrix metalloproteinase stromelysin-1 acts as a natural mammary tumor promoter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

Mutations in TNFRSF11A, affecting the signal peptide of RANK, cause familial expansile osteolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

Generation of biologically active IL-1 beta by matrix metalloproteinases: a novel caspase-1-independent pathway of IL-1 beta processing.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

The TIMP2 membrane type 1 metalloproteinase "receptor" regulates the concentration and efficient activation of progelatinase A. A kinetic study

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

Matrix metalloproteinases as insulin-like growth factor binding protein-degrading proteinases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

Matrix metalloproteinase 2 releases active soluble ectodomain of fibroblast growth factor receptor 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

Matrix metalloproteinase 2 (gelatinase A) regulates glomerular mesangial cell proliferation and differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

Spondyloepimetaphyseal dysplasia: clinical and radiologic investigation of a large kindred manifesting autosomal dominant inheritance, and a review of the literature.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

Mechanism of cell surface activation of 72-kDa type IV collagenase. Isolation of the activated form of the membrane metalloprotease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

Metalloproteinases from rabbit bone culture medium degrade types IV and V collagens, laminin and fibronectin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

Essential osteolysis with nephropathy. A review of the literature and case report of an unusual syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

Collagenase in synovitis of rheumatoid arthritis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

Idiopathic multicentric osteolysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

25 May 2018

A crucial role for matrix metalloproteinase 2 in osteocytic canalicular formation and bone metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

15 August 2018

Targeted inhibition of the KLF6 splice variant, KLF6 SV1, suppresses prostate cancer cell growth and spread.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

15 August 2018

The metalloproteinase MT1-MMP is required for normal development and maintenance of osteocyte processes in bone.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

15 August 2018

The expression of gelatinase A (MMP-2) is required for normal development of zebrafish embryos

1 reference

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15 August 2018

Osteopontin, a novel substrate for matrix metalloproteinase-3 (stromelysin-1) and matrix metalloproteinase-7 (matrilysin).

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

15 August 2018

International nomenclature and classification of the osteochondrodysplasias (1997).

1 reference

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15 August 2018

Unaltered secretion of beta-amyloid precursor protein in gelatinase A (matrix metalloproteinase 2)-deficient mice.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2576517

15 August 2018

Genetic determinants of bone mass

1 reference

https://pubmed.ncbi.nlm.nih.gov/17400654

12 December 2020

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Murine TIMP-2 gene-targeted mutation

1 reference

https://pubmed.ncbi.nlm.nih.gov/17400654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MT1-MMP-deficient mice develop dwarfism, osteopenia, arthritis, and connective tissue disease due to inadequate collagen turnover

1 reference

https://pubmed.ncbi.nlm.nih.gov/17400654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inherited multicentric osteolysis with arthritis: a variant resembling Torg syndrome in a Saudi family

1 reference

https://pubmed.ncbi.nlm.nih.gov/17400654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Don't mess with the matrix

1 reference

https://pubmed.ncbi.nlm.nih.gov/17400654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Radiological findings in NAO syndrome

1 reference

https://pubmed.ncbi.nlm.nih.gov/17400654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genetic control of bone remodeling--insights from a rare disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/17400654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of matrix metalloproteinase-2 and matrix metalloproteinase-9 in antibody-induced arthritis

1 reference

https://pubmed.ncbi.nlm.nih.gov/17400654

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1093/HMG/DDM060

1 reference

Europe PubMed Central

PMC publication ID

17 November 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

17 November 2017

ResearchGate publication ID

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