(Q43249056)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18702832%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

title

Recombinant human activated protein C attenuates endotoxin-induced lung injury in awake sheep (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18702832%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

1 reference

1 reference

1 reference

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18702832%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Mikhail Y. Kirov

3

1 reference

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12 January 2020

author name string

Kristine Waerhaug

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18702832%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Mikhail A Sovershaev

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18702832%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Bodil Langbakk

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18702832%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Ole C Ingebretsen

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18702832%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Kirsti Ytrehus

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18702832%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

Lars J Bjertnaes

8

1 reference

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12 January 2020

publication date

15 August 2008

1 reference

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12 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18702832%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

volume

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18702832%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

issue

4

1 reference

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12 January 2020

page(s)

R104

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18702832%20AND%20SRC:MED&resulttype=core&format=json

Tezosentan-induced attenuation of lung injury in endotoxemic sheep is associated with reduced activation of protein kinase C.

12 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575593

Endothelial barrier protection by activated protein C through PAR1-dependent sphingosine 1-phosphate receptor-1 crossactivation

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575593

Leukocyte and endothelial cell interactions in sepsis: relevance of the protein C pathway

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575593

Protein C and thrombomodulin in human acute lung injury

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575593

Molecular mechanisms of thrombin-induced endothelial cell permeability

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575593

Efficacy and safety of recombinant human activated protein C for severe sepsis

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575593

The acute respiratory distress syndrome

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575593

The American-European Consensus Conference on ARDS. Definitions, mechanisms, relevant outcomes, and clinical trial coordination

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575593

Protein C prevents the coagulopathic and lethal effects of Escherichia coli infusion in the baboon

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575593

Influence of steroidal and nonsteroidal anti-inflammatory agents on the accumulation of arachidonic acid metabolites in plasma and lung lymph after endotoxemia in awake sheep. Measurements of prostacyclin and thromboxane metabolites and 12-HETE.

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575593

Circulating interleukin-1 and tumor necrosis factor in septic shock and experimental endotoxin fever

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575593

Time course of plasma and pulmonary lymph endothelin-like immunoreactivity during sustained endotoxaemia in chronically instrumented sheep

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575593

Increased sheep lung vascular permeability caused by Escherichia coli endotoxin

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575593

Beneficial effects of recombinant human activated protein C in a ewe model of septic shock

25 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575593

Protein C concentrations in severe sepsis: an early directional change in plasma levels predicts outcome

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575593

Extravascular lung water to blood volume ratios as measures of permeability in sepsis-induced ALI/ARDS.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575593

Activated protein C mediates novel lung endothelial barrier enhancement: role of sphingosine 1-phosphate receptor transactivation

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575593

Novel endothelin receptor antagonist attenuates endotoxin-induced lung injury in sheep.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575593

Fluid challenge in patients at risk for fluid loading-induced pulmonary edema.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575593

Blockade of tissue factor: treatment for organ injury in established sepsis.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575593

Imbalances between the levels of tissue factor and tissue factor pathway inhibitor in ARDS patients

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575593

Effects of drotrecogin alfa (activated) on organ dysfunction in the PROWESS trial.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575593

Evaluation of unfractionated heparin and recombinant hirudin on survival in a sustained ovine endotoxin shock model.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575593

Activated protein C inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production by inhibiting activation of both nuclear factor-kappa B and activator protein-1 in human monocytes.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575593

Inhaled nitric oxide reduces lung fluid filtration after endotoxin in awake sheep.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575593

Respiratory failure after endotoxin infusion in sheep: lung mechanics and lung fluid balance.

15 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2575593

Activated protein C attenuates endotoxin-induced pulmonary vascular injury by inhibiting activated leukocytes in rats

15 August 2018

1 reference

12 December 2020

TNF-alpha and the pathophysiology of endotoxin-induced acute respiratory failure in sheep

1 reference

12 December 2020

Activated protein C prevents LPS-induced pulmonary vascular injury by inhibiting cytokine production

1 reference

12 December 2020

Treating patients with severe sepsis

1 reference

12 December 2020

Recombinant human activated protein C reduces human endotoxin-induced pulmonary inflammation via inhibition of neutrophil chemotaxis

1 reference

12 December 2020

Extravascular lung water determined with single transpulmonary thermodilution correlates with the severity of sepsis-induced acute lung injury

1 reference

12 December 2020

Effect of recombinant activated protein C and low-dose heparin on neutrophil-endothelial cell interactions in septic shock

1 reference

12 December 2020

Recombinant human activated protein C improves pulmonary function in ovine acute lung injury resulting from smoke inhalation and sepsis

1 reference

12 December 2020

Extravascular lung water after pneumonectomy and one-lung ventilation in sheep

1 reference

12 December 2020

Comparison of the human and canine cytokines IL-1(alpha/beta) and TNF-alpha to orthologous other mammalians

1 reference

12 December 2020

Endotoxemia-induced leukopenia in sheep. Correlation with lung vascular permeability and hypoxemia but not with pulmonary hypertension

1 reference

12 December 2020

Prevention of rabbit acute lung injury by surfactant, inhaled nitric oxide, and pressure support ventilation

1 reference

12 December 2020

The Protein C Pathway

1 reference

12 December 2020

Identifiers

DOI

10.1186/CC6985

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18702832%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

12 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18702832%20AND%20SRC:MED&resulttype=core&format=json

12 January 2020

PubMed publication ID

18702832

1 reference