(Q43292661)

18 November 2017

title

Pan-caspase inhibitor VX-166 reduces fibrosis in an animal model of nonalcoholic steatohepatitis (English)

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18 November 2017

7

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18 November 2017

Rafal P Witek

1

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18 November 2017

W Carl Stone

2

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18 November 2017

F Gamze Karaca

3

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18 November 2017

Wing-Kin Syn

4

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18 November 2017

Thiago A Pereira

5

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18 November 2017

Kolade M Agboola

6

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18 November 2017

Youngmi Jung

8

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18 November 2017

Vanessa Teaberry

9

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18 November 2017

Steve S Choi

10

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18 November 2017

Cynthia D Guy

11

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18 November 2017

John Pollard

12

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18 November 2017

Peter Charlton

13

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18 November 2017

Anna Mae Diehl

14

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18 November 2017

language of work or name

English

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publication date

1 November 2009

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18 November 2017

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18 November 2017

volume

50

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18 November 2017

issue

5

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18 November 2017

page(s)

1421-1430

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Definition and natural history of metabolic steatosis: clinical aspects of NAFLD, NASH and cirrhosis

18 November 2017

cites work

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CD95-induced apoptosis in human liver disease

21 January 2018

1 reference

Death receptor-mediated apoptosis and the liver

21 January 2018

1 reference

Fas enhances fibrogenesis in the bile duct ligated mouse: a link between apoptosis and fibrosis.

21 January 2018

1 reference

Proteases for cell suicide: functions and regulation of caspases

21 January 2018

1 reference

Apoptosis and necrosis in the liver: a tale of two deaths?

21 January 2018

1 reference

Polyunsaturated fat in the methionine-choline-deficient diet influences hepatic inflammation but not hepatocellular injury

21 January 2018

1 reference

Hepatic lipid partitioning and liver damage in nonalcoholic fatty liver disease: role of stearoyl-CoA desaturase

21 January 2018

1 reference

Obese and diabetic db/db mice develop marked liver fibrosis in a model of nonalcoholic steatohepatitis: role of short-form leptin receptors and osteopontin

21 January 2018

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Mechanisms of caspase activation and inhibition during apoptosis

21 January 2018

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Mitochondrial proteins that regulate apoptosis and necrosis are induced in mouse fatty liver

21 January 2018

1 reference

Hepatic accumulation of Hedgehog-reactive progenitors increases with severity of fatty liver damage in mice

21 January 2018

1 reference

Sustained activation of Rac1 in hepatic stellate cells promotes liver injury and fibrosis in mice.

21 January 2018

1 reference

Design and validation of a histological scoring system for nonalcoholic fatty liver disease

21 January 2018

1 reference

Mechanisms of disease progression in nonalcoholic fatty liver disease

21 January 2018

1 reference

The Caspase Inhibitor IDN-6556 Attenuates Hepatic Injury and Fibrosis in the Bile Duct Ligated Mouse

21 January 2018

1 reference

Apoptosis-induced compensatory proliferation. The Cell is dead. Long live the Cell!

21 January 2018

1 reference

Sonic hedgehog is an autocrine viability factor for myofibroblastic hepatic stellate cells

21 January 2018

1 reference

Hepatocyte apoptosis and fas expression are prominent features of human nonalcoholic steatohepatitis

21 January 2018

1 reference

7 January 2021

VX-166, a novel potent small molecule caspase inhibitor, as a promising new treatment for sepsis.

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7 January 2021

In vivo assessment of liver cell apoptosis as a novel biomarker of disease severity in nonalcoholic fatty liver disease

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7 January 2021

Hepatic stellate cells and fibrosis progression in patients with nonalcoholic fatty liver disease

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7 January 2021

Identifiers

DOI

10.1002/HEP.23167

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18 November 2017

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