(Q43294437)

English

Association of polymorphisms MTHFR C677T and A1298C with risk of colorectal cancer, genetic and epigenetic characteristic of tumors, and response to chemotherapy.

scientific article published on 11 August 2009

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scholarly article

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Europe PubMed Central

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5 February 2020

Association of polymorphisms MTHFR C677T and A1298C with risk of colorectal cancer, genetic and epigenetic characteristic of tumors, and response to chemotherapy (English)

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19669769%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

colorectal cancer

1 reference

based on heuristic

inferred from title

1 reference

based on heuristic

inferred from title

colorectal carcinoma

1 reference

based on heuristic

inferred from title

2

1 reference

Europe PubMed Central

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5 February 2020

author name string

Antonia M Fernández-Peralta

1

1 reference

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5 February 2020

Nargisse Nejda

3

1 reference

Europe PubMed Central

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5 February 2020

Daniel Iglesias

4

1 reference

Europe PubMed Central

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5 February 2020

Vicente Medina Arana

5

1 reference

Europe PubMed Central

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5 February 2020

Juan J González-Aguilera

6

1 reference

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5 February 2020

language of work or name

1 reference

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publication date

11 August 2009

1 reference

Europe PubMed Central

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5 February 2020

International Journal of Colorectal Disease

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19669769%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

25

1 reference

Europe PubMed Central

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5 February 2020

141-151

1 reference

Europe PubMed Central

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5 February 2020

2

1 reference

Europe PubMed Central

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5 February 2020

https://scigraph.springernature.com/pub.10.1007/s00384-009-0779-y

0 references

Polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene, intakes of folate and related B vitamins and colorectal cancer: a case-control study in a population with relatively low folate intake

1 reference

https://api.crossref.org/works/10.1007%2FS00384-009-0779-Y

21 January 2018

Characterisation of colorectal cancers showing hypermethylation at multiple CpG islands

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of MTHFR polymorphisms and folate levels in different phenotypes of sporadic colorectal cancers.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Do MSI-L sporadic colorectal tumors develop through "mild mutator pathway"?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Folate and carcinogenesis: an integrated scheme

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylenetetrahydrofolate reductase 677 C-->T polymorphism and risk of proximal colon cancer in north Italy.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of the methylenetetrahydrofolate reductase C677T polymorphism on chemosensitivity of colon and breast cancer cells to 5-fluorouracil and methotrexate

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Colorectal adenomas and the C677T MTHFR polymorphism: evidence for gene-environment interaction?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylenetetrahydrofolate reductase polymorphisms and risk of sporadic and hereditary colorectal cancer with or without microsatellite instability

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polymorphisms of methylenetetrahydrofolate reductase and other enzymes: metabolic significance, risks and impact on folate requirement

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Folate intake, alcohol consumption, cigarette smoking, and risk of colorectal adenomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A second common mutation in the methylenetetrahydrofolate reductase gene: an additional risk factor for neural-tube defects?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A second genetic polymorphism in methylenetetrahydrofolate reductase (MTHFR) associated with decreased enzyme activity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Genomic DNA hypomethylation, a characteristic of most cancers, is present in peripheral leukocytes of individuals who are homozygous for the C677T polymorphism in the methylenetetrahydrofolate reductase gene

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Significance of mutations in TGFBR2 and BAX in neoplastic progression and patient outcome in sporadic colorectal tumors with high-frequency microsatellite instability

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Case for folic acid and vitamin B12 fortification in Europe

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5,10-Methylenetetrahydrofolate reductase codon 677 and 1298 polymorphisms and colon cancer in African Americans and whites

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylenetetrahydrofolate reductase polymorphism is associated with folate pool in gastrointestinal cancer tissue

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thymidylate synthase promoter polymorphism, interaction with folate intake, and risk of colorectal adenomas.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Folate and carcinogenesis: evidence, mechanisms, and implications

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylenetetrahydrofolate reductase C677T and A1298C polymorphisms and colorectal cancer: the Fukuoka Colorectal Cancer Study

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Polymorphisms in methylenetetrahydrofolate reductase gene (MTHFR) and the age of onset of sporadic colorectal adenocarcinoma.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multifactor-dimensionality reduction reveals high-order interactions among estrogen-metabolism genes in sporadic breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Localized depletion: the key to colorectal cancer risk mediated by MTHFR genotype and folate?

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influence of methylenetetrahydrofolate reductase gene polymorphisms C677T and A1298C on age-associated risk for colorectal cancer in a caucasian lynch syndrome population

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Power of multifactor dimensionality reduction for detecting gene-gene interactions in the presence of genotyping error, missing data, phenocopy, and genetic heterogeneity

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Loss of heterozygosity of TP53 is not correlated with clinicopathological variables in sporadic colorectal carcinomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A methylenetetrahydrofolate reductase polymorphism and the risk of colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

5,10-Methylenetetrahydrofolate reductase polymorphisms and leukemia risk: a HuGE minireview

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylenetetrahydrofolate reductase polymorphism in advanced colorectal cancer: a novel genomic predictor of clinical response to fluoropyrimidine-based chemotherapy

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The prognostic significance of genetic polymorphisms (Methylenetetrahydrofolate Reductase C677T, Methionine Synthase A2756G, Thymidilate Synthase tandem repeat polymorphism) in multimodally treated oesophageal squamous cell carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylenetetrahydrofolate reductase, alcohol dehydrogenase, diet, and risk of colorectal adenomas

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Folate, Methyl-Related Nutrients, Alcohol, and the MTHFR 677C→T Polymorphism Affect Cancer Risk: Intake Recommendations

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylenetetrahydrofolate reductase polymorphism, dietary interactions, and risk of colorectal cancer.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Relation of plasma folate and methylenetetrahydrofolate reductase C677T polymorphism to colorectal adenomas.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Folate, Methionine, and Alcohol Intake and Risk of Colorectal Adenoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Simultaneous mutations in K-ras and TP53 are indicative of poor prognosis in sporadic colorectal cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

One-carbon metabolism, MTHFR polymorphisms, and risk of breast cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A common mutation in the methylenetetrahydrofolate reductase gene is associated with an accumulation of formylated tetrahydrofolates in red blood cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The 1298A-->C polymorphism in methylenetetrahydrofolate reductase (MTHFR): in vitro expression and association with homocysteine

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Multifactor dimensionality reduction software for detecting gene-gene and gene-environment interactions.

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of common polymorphisms on the properties of recombinant human methylenetetrahydrofolate reductase

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Methylenetetrahydrofolate reductase, diet, and risk of colon cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemoprevention effects on bronchial squamous metaplasia by folate and vitamin B12 in heavy smokers

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A polymorphism in the methylenetetrahydrofolate reductase gene predisposes to colorectal cancers with microsatellite instability

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MTHFR C677T and A1298C polymorphisms: diet, estrogen, and risk of colon cancer

1 reference

https://pubmed.ncbi.nlm.nih.gov/19669769

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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