(Q43488425)

English

Fusion intermediates of HIV-1 gp41 as targets for antibody production: design, synthesis, and HR1-HR2 complex purification and characterization of generated antibodies.

scientific article published in November 2010

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scholarly article

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15 February 2020

Fusion intermediates of HIV-1 gp41 as targets for antibody production: design, synthesis, and HR1-HR2 complex purification and characterization of generated antibodies (English)

1 reference

Europe PubMed Central

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15 February 2020

Ernest Giralt i Lledó

5

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15 February 2020

Elmostafa Bahraoui

6

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15 February 2020

author name string

Olfa Mzoughi

1

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15 February 2020

Fabrice Gaston

2

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15 February 2020

Giovana C Granados

3

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15 February 2020

Faouzi Lakhdar-Ghazal

4

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15 February 2020

publication date

1 November 2010

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15 February 2020

1 reference

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15 February 2020

5

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15 February 2020

11

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15 February 2020

1907-1918

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15 February 2020

The CD4 (T4) antigen is an essential component of the receptor for the AIDS retrovirus

1 reference

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7 January 2021

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T-lymphocyte T4 molecule behaves as the receptor for human retrovirus LAV

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7 January 2021

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Lymphadenopathy-associated viral antibody in AIDS. Immune correlations and definition of a carrier state

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Purification and characterization of a Ca2+-independent endoprotease activity from peripheral blood lymphocytes: involvement in HIV-1 gp160 maturation.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000313

7 January 2021

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A trimeric structural domain of the HIV-1 transmembrane glycoprotein.

1 reference

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7 January 2021

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Inhibition of HIV-2(ROD) replication in a lymphoblastoid cell line by the alpha1-antitrypsin Portland variant (alpha1-PDX) and the decRVKRcmk peptide: comparison with HIV-1(LAI).

1 reference

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7 January 2021

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Proteolytic cleavage of wild type and mutants of the F protein of human parainfluenza virus type 3 by two subtilisin-like endoproteases, furin and Kex2.

1 reference

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Processing of the Ebola virus glycoprotein by the proprotein convertase furin

1 reference

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Role of N-linked glycans in the interaction between the envelope glycoprotein of human immunodeficiency virus and its CD4 cellular receptor. Structural enzymatic analysis

1 reference

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7 January 2021

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Specificity of antibodies produced against native or desialylated human immunodeficiency virus type 1 recombinant gp160.

1 reference

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7 January 2021

based on heuristic

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N-linked oligosaccharides of simian immunodeficiency virus envelope glycoproteins are dispensable for the interaction with the CD4 receptor

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000313

7 January 2021

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Delineation of a region of the human immunodeficiency virus type 1 gp120 glycoprotein critical for interaction with the CD4 receptor

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000313

7 January 2021

based on heuristic

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Heptad repeat sequences are located adjacent to hydrophobic regions in several types of virus fusion glycoproteins

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000313

7 January 2021

based on heuristic

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HIV-1 gp41 six-helix bundle formation occurs rapidly after the engagement of gp120 by CXCR4 in the HIV-1 Env-mediated fusion process

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000313

7 January 2021

based on heuristic

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HIV-1 membrane fusion: targets of opportunity

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000313

7 January 2021

based on heuristic

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Covalent stabilization of coiled coils of the HIV gp41 N region yields extremely potent and broad inhibitors of viral infection

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000313

7 January 2021

based on heuristic

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The inhibitory activity of an HIV type 1 peptide correlates with its ability to interact with a leucine zipper structure

1 reference

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7 January 2021

based on heuristic

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Potent suppression of HIV-1 replication in humans by T-20, a peptide inhibitor of gp41-mediated virus entry

1 reference

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7 January 2021

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Mode of action of an antiviral peptide from HIV-1. Inhibition at a post-lipid mixing stage

1 reference

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7 January 2021

based on heuristic

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Design of a novel peptide inhibitor of HIV fusion that disrupts the internal trimeric coiled-coil of gp41.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000313

7 January 2021

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T-1249 retains potent antiretroviral activity in patients who had experienced virological failure while on an enfuvirtide-containing treatment regimen

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000313

7 January 2021

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Design and evaluation of sifuvirtide, a novel HIV-1 fusion inhibitor

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000313

7 January 2021

based on heuristic

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Evidence that a prominent cavity in the coiled coil of HIV type 1 gp41 is an attractive drug target

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000313

7 January 2021

based on heuristic

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Development and characterization of peptidic fusion inhibitors derived from HIV-1 gp41 with partial D-amino acid substitutions.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000313

7 January 2021

based on heuristic

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Remodeling of dynamic structures of HIV-1 envelope proteins leads to synthetic antigen molecules inducing neutralizing antibodies.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000313

7 January 2021

based on heuristic

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Peptides corresponding to the heptad repeat motifs in the transmembrane protein (gp41) of human immunodeficiency virus type 1 elicit antibodies to receptor-activated conformations of the envelope glycoprotein

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000313

7 January 2021

based on heuristic

inferred from DOI database lookup

Core structure of gp41 from the HIV envelope glycoprotein

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000313

7 January 2021

based on heuristic

inferred from DOI database lookup

Trifluoroethanol promotes helix formation by destabilizing backbone exposure: desolvation rather than native hydrogen bonding defines the kinetic pathway of dimeric coiled coil folding

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000313

7 January 2021

based on heuristic

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Evidence that the transition of HIV-1 gp41 into a six-helix bundle, not the bundle configuration, induces membrane fusion

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000313

7 January 2021

based on heuristic

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Analysis of PDZ domain-ligand interactions using carboxyl-terminal phage display

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000313

7 January 2021

based on heuristic

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Neutralization of human T-lymphotropic virus type III by sera of AIDS and AIDS-risk patients

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000313

7 January 2021

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The role of antibodies in HIV vaccines

1 reference

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7 January 2021

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The mannose-dependent epitope for neutralizing antibody 2G12 on human immunodeficiency virus type 1 glycoprotein gp120.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000313

7 January 2021

based on heuristic

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In vivo gp41 antibodies targeting the 2F5 monoclonal antibody epitope mediate human immunodeficiency virus type 1 neutralization breadth

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000313

7 January 2021

based on heuristic

inferred from DOI database lookup

Identification of a second site in HIV-1 gp41 mediating binding to cells

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000313

7 January 2021

based on heuristic

inferred from DOI database lookup

Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000313

7 January 2021

based on heuristic

inferred from DOI database lookup

Recognition properties of a panel of human recombinant Fab fragments to the CD4 binding site of gp120 that show differing abilities to neutralize human immunodeficiency virus type 1.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000313

7 January 2021

based on heuristic

inferred from DOI database lookup

Rational design of envelope identifies broadly neutralizing human monoclonal antibodies to HIV-1

1 reference

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7 January 2021

based on heuristic

inferred from DOI database lookup

Factors associated with the development of cross-reactive neutralizing antibodies during human immunodeficiency virus type 1 infection

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000313

7 January 2021

based on heuristic

inferred from DOI database lookup

Correlation between humoral responses to human immunodeficiency virus type 1 envelope and disease progression in early-stage infection

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000313

7 January 2021

based on heuristic

inferred from DOI database lookup

Association of antibody reactivity to ELDKWA, a glycoprotein 41 neutralization epitope, with disease progression in children perinatally infected with HIV type 1

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000313

7 January 2021

based on heuristic

inferred from DOI database lookup

A conformation-specific monoclonal antibody reacting with fusion-active gp41 from the human immunodeficiency virus type 1 envelope glycoprotein.

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000313

7 January 2021

based on heuristic

inferred from DOI database lookup

Dissection of human immunodeficiency virus type 1 entry with neutralizing antibodies to gp41 fusion intermediates

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000313

7 January 2021

based on heuristic

inferred from DOI database lookup

Analysis of circular dichroism data

1 reference

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based on heuristic

inferred from DOI database lookup

Computation and analysis of protein circular dichroism spectra

1 reference

https://api.crossref.org/works/10.1002%2FCMDC.201000313

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1002/CMDC.201000313

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20922745%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20922745%20AND%20SRC:MED&resulttype=core&format=json

15 February 2020

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