(Q43517960)

24 November 2017

title

The role of glutathione in the isomerization of delta 5-androstene-3,17-dione catalyzed by human glutathione transferase A1-1. (English)

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Glutathione S-transferase alpha 1

24 November 2017

main subject

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steroid delta-isomerase activity

GOA release 2020-03-11

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GOA release 2020-03-11

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Pettersson PL

1

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24 November 2017

Mannervik B

series ordinal

2

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24 November 2017

language of work or name

English

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publication date

10 January 2001

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Journal of Biological Chemistry

24 November 2017

published in

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24 November 2017

volume

276

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24 November 2017

issue

15

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24 November 2017

page(s)

11698-11704

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Enzymic isomerization of delta5-3-ketosteroids

24 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009146200

Human placental 3 beta-hydroxy-5-ene-steroid dehydrogenase and steroid 5----4-ene-isomerase: purification from mitochondria and kinetic profiles, biophysical characterization of the purified mitochondrial and microsomal enzymes

21 January 2018

1 reference

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Role of reduced glutathione in the Δ5-3-ketosteroid isomerase reaction of liver

21 January 2018

1 reference

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Relationship between the soluble glutathione-dependent delta 5-3-ketosteroid isomerase and the glutathione S-transferases of the liver

21 January 2018

1 reference

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Nomenclature for human glutathione transferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009146200

Identification of three classes of cytosolic glutathione transferase common to several mammalian species: correlation between structural data and enzymatic properties

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009146200

Characterization of rat spleen prostaglandin H D-isomerase as a sigma-class GSH transferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009146200

Glutathione S-transferase class Kappa: characterization by the cloning of rat mitochondrial GST and identification of a human homologue

21 January 2018

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Zeta, a novel class of glutathione transferases in a range of species from plants to humans

21 January 2018

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Identification, characterization, and crystal structure of the Omega class glutathione transferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009146200

Structure determination and refinement of human alpha class glutathione transferase A1-1, and a comparison with the Mu and Pi class enzymes

21 January 2018

1 reference

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Location of a potential transport binding site in a sigma class glutathione transferase by x-ray crystallography

21 January 2018

1 reference

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Crystal structures of a schistosomal drug and vaccine target: glutathione S-transferase from Schistosoma japonica and its complex with the leading antischistosomal drug praziquantel

21 January 2018

1 reference

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The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance

21 January 2018

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Structure, catalytic mechanism, and evolution of the glutathione transferases

21 January 2018

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Glutathione transferases and cancer

21 January 2018

1 reference

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X-ray crystal structures of cytosolic glutathione S-transferases. Implications for protein architecture, substrate recognition and catalytic function

21 January 2018

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Structure and function of glutathione S-transferases.

21 January 2018

1 reference

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Mechanism-based phage display selection of active-site mutants of human glutathione transferase A1-1 catalyzing SNAr reactions

21 January 2018

1 reference

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Evolution of differential substrate specificities in Mu class glutathione transferases probed by DNA shuffling

21 January 2018

1 reference

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Heterologous expression of recombinant human glutathione transferase A1-1 from a hepatoma cell line

21 January 2018

1 reference

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The basic glutathione S-transferases from human livers are products of separate genes

21 January 2018

1 reference

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Glutathione Transferases with Novel Active Sites Isolated by Phage Display from a Library of Random Mutants

21 January 2018

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Benzoic acid derivatives induce recovery of catalytic activity in the partially inactive Met208Lys mutant of human glutathione transferase A1-1

21 January 2018

1 reference

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Human glutathione transferase A4-4: an alpha class enzyme with high catalytic efficiency in the conjugation of 4-hydroxynonenal and other genotoxic products of lipid peroxidation

21 January 2018

1 reference

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Involvement of the carboxyl groups of glutathione in the catalytic mechanism of human glutathione transferase A1-1.

21 January 2018

1 reference

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The kinetics of enzyme-catalyzed reactions with two or more substrates or products

21 January 2018

1 reference

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The C-terminal region of human glutathione transferase A1-1 affects the rate of glutathione binding and the ionization of the active-site Tyr9.

21 January 2018

1 reference

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Probing subunit interactions in alpha class rat liver glutathione S-transferase with the photoaffinity label glutathionyl S-[4-(succinimidyl)benzophenone]

21 January 2018

1 reference

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Functional significance of arginine 15 in the active site of human class alpha glutathione transferase A1-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009146200

Positioning of a spin-labeled substrate analogue into the structure of delta 5-3-ketosteroid isomerase by combined kinetic, magnetic resonance, and X-ray diffraction methods

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009146200

Solution structure of Delta 5-3-ketosteroid isomerase complexed with the steroid 19-nortestosterone hemisuccinate

21 January 2018

1 reference

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Electrophilic assistance by Asp-99 of 3-oxo-Delta 5-steroid isomerase.

21 January 2018

1 reference

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Site-directed mutagenesis identifies amino acid residues associated with the dehydrogenase and isomerase activities of human type I (placental) 3beta-hydroxysteroid dehydrogenase/isomerase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009146200

The multiple murine 3 beta-hydroxysteroid dehydrogenase isoforms: structure, function, and tissue- and developmentally specific expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009146200

Glutathione transferases catalyse the detoxication of oxidized metabolites (o-quinones) of catecholamines and may serve as an antioxidant system preventing degenerative cellular processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009146200

Evidence for distinct dehydrogenase and isomerase sites within a single 3.beta.-hydroxysteroid dehydrogenase/5-ene-4-ene isomerase protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009146200

Subunit diversity and tissue distribution of human glutathione S-transferases: interpretations based on electrospray ionization-MS and peptide sequence-specific antisera

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009146200

Cloning and heterologous expression of cDNA encoding class Alpha rat glutathione transferase 8-8, an enzyme with high catalytic activity towards genotoxic α,β-unsaturated carbonyl compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009146200

The Conserved N-capping Box in the Hydrophobic Core of GlutathioneS-Transferase P1–1 Is Essential for Refolding

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M009146200

21 January 2018

Identifiers

DOI

10.1074/JBC.M009146200

1 reference

24 November 2017

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