(Q43534131)

English

Species extrapolation of life-stage physiologically-based pharmacokinetic (PBPK) models to investigate the developmental toxicology of ethanol using in vitro to in vivo (IVIVE) methods

scientific article published on 18 November 2014

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scholarly article

1 reference

Europe PubMed Central

24 November 2017

Species extrapolation of life-stage physiologically-based pharmacokinetic (PBPK) models to investigate the developmental toxicology of ethanol using in vitro to in vivo (IVIVE) methods (English)

1 reference

Europe PubMed Central

24 November 2017

pharmacokinetics

1 reference

based on heuristic

inferred from title

author name string

Sheppard A Martin

1

1 reference

Europe PubMed Central

24 November 2017

Eva D McLanahan

2

1 reference

Europe PubMed Central

24 November 2017

Philip J Bushnell

3

1 reference

Europe PubMed Central

24 November 2017

E Sidney Hunter

4

1 reference

Europe PubMed Central

24 November 2017

Hisham El-Masri

5

1 reference

Europe PubMed Central

24 November 2017

publication date

18 November 2014

1 reference

Europe PubMed Central

24 November 2017

Toxicological Sciences

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Europe PubMed Central

24 November 2017

143

1 reference

Europe PubMed Central

24 November 2017

2

1 reference

Europe PubMed Central

24 November 2017

512-535

1 reference

Europe PubMed Central

24 November 2017

Fetal alcohol syndrome: a cautionary note

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Prenatal ethanol exposure reduces the expression of the transcriptional factor Pax6 in the developing rat brain

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Disposition of ethanol in human maternal venous blood and amniotic fluid

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Physiological parameter values for physiologically based pharmacokinetic models

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Blood ethanol concentration profiles: a comparison between rats and mice

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Ethanol blocks both basic fibroblast growth factor- and carbachol-mediated neuroepithelial cell expansion with differential effects on carbachol-activated signaling pathways

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Development of multi-route physiologically-based pharmacokinetic models for ethanol in the adult, pregnant, and neonatal rat.

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Use of novel inhalation kinetic studies to refine physiologically-based pharmacokinetic models for ethanol in non-pregnant and pregnant rats.

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Acute effects of ethanol on brain, plasma and adrenal monoamine concentrations in virgin and pregnant rats and their fetuses.

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Maternal ethanol exposure induces transient impairment of umbilical circulation and fetal hypoxia in monkeys.

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Human embryonic stem cell model of ethanol-mediated early developmental toxicity.

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Identifiers

10.1093/TOXSCI/KFU246

1 reference

Europe PubMed Central

24 November 2017

1 reference

Europe PubMed Central

24 November 2017

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