(Q43540470)

English

Reduction of potassium currents and phosphatidylinositol 3-kinase-dependent AKT phosphorylation by tumor necrosis factor-(alpha) rescues axotomized retinal ganglion cells from retrograde cell death in vivo.

scientific article published in March 2001

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scholarly article

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Europe PubMed Central

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5 November 2019

Reduction of potassium currents and phosphatidylinositol 3-kinase-dependent AKT phosphorylation by tumor necrosis factor-(alpha) rescues axotomized retinal ganglion cells from retrograde cell death in vivo (English)

1 reference

Europe PubMed Central

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5 November 2019

phosphorylation

1 reference

based on heuristic

inferred from title

retinal ganglion cell

1 reference

based on heuristic

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1 reference

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author name string

R Diem

1

1 reference

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5 November 2019

R Meyer

2

1 reference

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5 November 2019

J H Weishaupt

3

1 reference

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5 November 2019

M Bahr

4

1 reference

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5 November 2019

language of work or name

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publication date

1 March 2001

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5 November 2019

Journal of Neuroscience

1 reference

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5 November 2019

21

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5 November 2019

2058-2066

1 reference

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5 November 2019

6

1 reference

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5 November 2019

TNF-alpha receptor fusion protein prevents experimental auto-immune encephalomyelitis and demyelination in Lewis rats: an overview

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular K+ suppresses the activation of apoptosis in lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Calcium activation of Ras mediated by neuronal exchange factor Ras-GRF.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vitro identification of retinal ganglion cells in culture without the need of dye labeling

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

An endotoxin-induced serum factor that causes necrosis of tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of cell volume loss in CEM-C7A cells during dexamethasone-induced apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Expression and clustered distribution of an inwardly rectifying potassium channel, KAB-2/Kir4.1, on mammalian retinal Müller cell membrane: their regulation by insulin and laminin signals

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Monoclonal Antibody to Thy-1 Enhances Regeneration of Processes by Rat Retinal Ganglion Cells In Culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human eosinophils in culture undergo a striking and rapid shrinkage during apoptosis. Role of K+ channels

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Retinal ganglion cell axons recognize specific guidance cues present in the deafferented adult rat superior colliculus.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor induces Bcl-2 and Bcl-x expression through NFkappaB activation in primary hippocampal neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Up-regulation of Bax protein in degenerating retinal ganglion cells precedes apoptotic cell death after optic nerve lesion in the rat

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potassium channel activators abolish excitotoxicity in cultured hippocampal pyramidal neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of CPP32-like proteases rescues axotomized retinal ganglion cells from secondary cell death in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuronal apoptosis induced by HIV-1 Tat protein and TNF-alpha: potentiation of neurotoxicity mediated by oxidative stress and implications for HIV-1 dementia.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor. Characterization at the molecular, cellular and in vivo level

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of ionic strength on the catalysis and stability of prolyl oligopeptidase

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TGF-beta-induced apoptosis of cerebellar granule neurons is prevented by depolarization

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Influences of peripheral nerve grafts on the survival and regrowth of axotomized retinal ganglion cells in adult rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Both the neuronal and inducible isoforms contribute to upregulation of retinal nitric oxide synthase activity by brain-derived neurotrophic factor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor-alpha contributes to apoptosis in hippocampal neurons during experimental group B streptococcal meningitis.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-6 selectively enhances the intracellular calcium response to NMDA in developing CNS neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factors protect neurons against metabolic-excitotoxic insults and promote maintenance of calcium homeostasis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Absence of volume regulatory mechanisms contributes to the rapid activation of apoptosis in thymocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Regulation of cell death protease caspase-9 by phosphorylation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo neurotrophic effects of GDNF on axotomized retinal ganglion cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Phosphatidylinositol 3-kinase as a mediator of TNF-induced NF-kappa B activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cytokine production in the brain following closed head injury: dexanabinol (HU-211) is a novel TNF-alpha inhibitor and an effective neuroprotectant

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Voltage-dependent conductances of solitary ganglion cells dissociated from the rat retina

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of tumor necrosis factor and amelioration of brain infarction in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Reciprocal actions of interleukin-6 and brain-derived neurotrophic factor on rat and mouse primary sensory neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Insulin-like growth factor-I protects axotomized rat retinal ganglion cells from secondary death via PI3-K-dependent Akt phosphorylation and inhibition of caspase-3 In vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor-alpha. A mediator of focal ischemic brain injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor enhancement of transient outward potassium currents in cultured rat cortical neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Ischemic and excitotoxic brain injury is enhanced in mice lacking the p55 tumor necrosis factor receptor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Long-term effect of inhibition of ced 3-like caspases on the survival of axotomized retinal ganglion cells in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis in cerebellar granule cells is blocked by high KCl, forskolin, and IGF-1 through distinct mechanisms of action: the involvement of intracellular calcium and RNA synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Protective effects of the TNF-ceramide pathway against glutamate neurotoxicity on cultured mesencephalic neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Flunarizine enhances rat retinal ganglion cell survival after axotomy

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Free radical scavenging and inhibition of nitric oxide synthase potentiates the neurotrophic effects of brain-derived neurotrophic factor on axotomized retinal ganglion cells In vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The transcription factor NF-kappaB mediates increases in calcium currents and decreases in NMDA- and AMPA/kainate-induced currents induced by tumor necrosis factor-alpha in hippocampal neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Characterization of the signaling interactions that promote the survival and growth of developing retinal ganglion cells in culture

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Depolarization and cAMP elevation rapidly recruit TrkB to the plasma membrane of CNS neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effects of ocular injury and administration of brain-derived neurotrophic factor on survival and regrowth of axotomized retinal ganglion cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Perspectives on axonal regeneration in the mammalian CNS.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of tumor necrosis factor alpha (TNFalpha) activity in rat brain is associated with cerebroprotection after closed head injury.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cleavage of the Lys196-Ser197 bond of prolyl oligopeptidase: enhanced catalytic activity for one of the two active enzyme forms

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Activation of caspase-3 in axotomized rat retinal ganglion cells in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptotic cell death induced by optic nerve lesion in the neonatal rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mediation of neuronal apoptosis by enhancement of outward potassium current.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

MK-801 reduces retinal ganglion cell survival but improves visual performance after controlled optic nerve crush.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor alpha inhibits glutamate uptake by primary human astrocytes. Implications for pathogenesis of HIV-1 dementia

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanism of activation of protein kinase B by insulin and IGF-1

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inhibition of tumor necrosis factor-alpha reduces focal cerebral ischemic injury in the spontaneously hypertensive rat.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Immunological, morphological, and electrophysiological variation among retinal ganglion cells purified by panning

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

TNF-induced signaling in apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Death receptors: signaling and modulation

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Depolarization and neurotrophins converge on the phosphatidylinositol 3-kinase-Akt pathway to synergistically regulate neuronal survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intravitreal injections of neurotrophic factors support the survival of axotomized retinal ganglion cells in adult rats in vivo.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Apoptosis in adult retinal ganglion cells after axotomy

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor induces phosphorylation and translocation of BAD through a phosphatidylinositide-3-OH kinase-dependent pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Intracellular ionic variations in the apoptotic death of L cells by inhibitors of cell cycle progression.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Tumor necrosis factor is a brain damaging cytokine in cerebral ischemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Potassium channel openers require ATP to bind to and act through sulfonylurea receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PI3K: downstream AKTion blocks apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

K+ channel openers protect hippocampal neurons against oxidative injury and amyloid beta-peptide toxicity.

1 reference

https://pubmed.ncbi.nlm.nih.gov/11245689

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1523/JNEUROSCI.21-06-02058.2001

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11245689%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11245689%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11245689%20AND%20SRC:MED&resulttype=core&format=json

5 November 2019

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