(Q43554143)

24 November 2017

title

Dichloroacetate: population pharmacokinetics with a pharmacodynamic sequential link model (English)

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24 November 2017

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Williams PJ

1

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24 November 2017

Lane JR

2

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24 November 2017

Turkel CC

3

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24 November 2017

Capparelli EV

4

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24 November 2017

Dziewanowska Z

5

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24 November 2017

Fox AW

6

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24 November 2017

publication date

1 March 2001

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The Journal of Clinical Pharmacology

24 November 2017

published in

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24 November 2017

volume

41

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24 November 2017

issue

3

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24 November 2017

page(s)

259-267

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Mechanism of activation of pyruvate dehydrogenase by dichloroacetate and other halogenated carboxylic acids

24 November 2017

cites work

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https://api.crossref.org/works/10.1177%2F00912700122010078

A controlled clinical trial of dichloroacetate for treatment of lactic acidosis in adults. The Dichloroacetate-Lactic Acidosis Study Group

21 January 2018

1 reference

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Effects of dichloroacetate in spinal stroke in the rabbit

21 January 2018

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https://api.crossref.org/works/10.1177%2F00912700122010078

Effect of dichloroacetate on recovery of brain lactate, phosphorus energy metabolites, and glutamate during reperfusion after complete cerebral ischemia in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122010078

Effects of sodium dichloroacetate dose. Brain metabolites associated with cerebral ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122010078

Inhibition of lactate-induced swelling by dichloroacetate in human astrocytoma cells

21 January 2018

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The neurochemical and metabolic cascade following brain injury: moving from animal models to man.

21 January 2018

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The prognostic and therapeutic importance of changes in the CSF during the acute stage of brain injury

21 January 2018

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Serial CSF lactate-pyruvate values as a guide to prognosis in head injury coma.

21 January 2018

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Prognostic significance of ventricular CSF lactic acidosis in severe head injury

21 January 2018

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https://api.crossref.org/works/10.1177%2F00912700122010078

Some correlations between the clinical outcome and the acid-base status of blood and cerebrospinal fluid in patients with traumatic brain injury

21 January 2018

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Lactate accumulation following concussive brain injury: the role of ionic fluxes induced by excitatory amino acids.

21 January 2018

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Acid-base balance and arterial and CSF lactate levels following human head injury

21 January 2018

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Clinical pharmacology and toxicology of dichloroacetate

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122010078

Clinical Pharmacokinetics of Hypnotics

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122010078

Dichloroacetate tissue concentrations and its relationship to hypolactatemia and pyruvate dehydrogenase activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122010078

Effects of dichloroacetate on brain pyruvate dehydrogenase

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122010078

Short-term dichloroacetate treatment improves indices of cerebral metabolism in patients with mitochondrial disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122010078

Physiologic indirect response models characterize diverse types of pharmacodynamic effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122010078

Pharmacokinetics of dichloroacetate in adult patients with lactic acidosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122010078

Biological disposition of sodium dichloroacetate in animals and humans after intravenous administration

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122010078

Metabolic effects and pharmacokinetics of intravenously administered dichloroacetate in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1177%2F00912700122010078

10.1177/00912700122010078

21 January 2018

Identifiers

DOI

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release_ilkn76ii6fdmliw62wijbkbbgi

24 November 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ilkn76ii6fdmliw62wijbkbbgi

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference