(Q43559426)

English

Oxidation of thymine to 5-formyluracil in DNA promotes misincorporation of dGMP and subsequent elongation of a mismatched primer terminus by DNA polymerase

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

24 November 2017

Oxidation of thymine to 5-formyluracil in DNA promotes misincorporation of dGMP and subsequent elongation of a mismatched primer terminus by DNA polymerase (English)

1 reference

Europe PubMed Central

PubMed publication ID

24 November 2017

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author name string

Masaoka A

1

1 reference

Europe PubMed Central

PubMed publication ID

24 November 2017

Terato H

2

1 reference

Europe PubMed Central

PubMed publication ID

24 November 2017

Kobayashi M

3

1 reference

Europe PubMed Central

PubMed publication ID

24 November 2017

Ohyama Y

4

1 reference

Europe PubMed Central

PubMed publication ID

24 November 2017

Ide H

5

1 reference

Europe PubMed Central

PubMed publication ID

24 November 2017

language of work or name

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publication date

29 January 2001

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Europe PubMed Central

PubMed publication ID

24 November 2017

number of pages

10

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inferred from page(s)

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

24 November 2017

276

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Europe PubMed Central

PubMed publication ID

24 November 2017

19

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Europe PubMed Central

PubMed publication ID

24 November 2017

16501-16510

1 reference

Europe PubMed Central

PubMed publication ID

24 November 2017

Fidelity mechanisms in DNA replication

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Conformational coupling in DNA polymerase fidelity

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Mismatch repair in replication fidelity, genetic recombination, and cancer biology

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Reactions of oxyl radicals with DNA.

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Effects on sister chromatid exchange frequency of aldehyde dehydrogenase 2 genotype and smoking in vinyl chloride workers.

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The many faces of DNA polymerases: strategies for mutagenesis and for mutational avoidance

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Uniquely altered DNA replication fidelity conferred by an amino acid change in the nucleotide binding pocket of human immunodeficiency virus type 1 reverse transcriptase

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DNA polymerases: structural diversity and common mechanisms

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Repair and replication of oxidized DNA bases using modified oligodeoxyribonucleotides

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Thymine ring saturation and fragmentation products: lesion bypass, misinsertion and implications for mutagenesis.

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Thymine glycols and urea residues in M13 DNA constitute replicative blocks in vitro.

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Synthesis of dihydrothymidine and thymidine glycol 5'-triphosphates and their ability to serve as substrates for Escherichia coli DNA polymerase I.

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Dihydrothymidine and thymidine glycol triphosphates as substrates for DNA polymerases: differential recognition of thymine C5-C6 bond saturation and sequence specificity of incorporation.

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On the mechanism of preferential incorporation of dAMP at abasic sites in translesional DNA synthesis. Role of proofreading activity of DNA polymerase and thermodynamic characterization of model template-primers containing an abasic site

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Replication bypass and mutagenic effect of alpha-deoxyadenosine site-specifically incorporated into single-stranded vectors

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Oxidative damage in DNA. Lack of mutagenicity by thymine glycol lesions.

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Pyrimidine ring fragmentation products. Effects of lesion structure and sequence context on mutagenesis.

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Site directed substitution of 5-hydroxymethyluracil for thymine in replicating phi X-174am3 DNA via synthesis of 5-hydroxymethyl-2'-deoxyuridine-5'-triphosphate

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Lack of phenotypic alteration of hmUra-DNA glycosylase-deficient hamster cells exposed to DNA-damaging agents

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Substrate and mispairing properties of 5-formyl-2'-deoxyuridine 5'-triphosphate assessed by in vitro DNA polymerase reactions

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Enzymatic repair of 5-formyluracil. II. Mismatch formation between 5-formyluracil and guanine during dna replication and its recognition by two proteins involved in base excision repair (AlkA) and mismatch repair (MutS).

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Replication of DNA templates containing 5-formyluracil, a major oxidative lesion of thymine in DNA

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A mutant of DNA polymerase I (Klenow fragment) with reduced fidelity

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DNA polymerase beta: structure-fidelity relationship from Pre-steady-state kinetic analyses of all possible correct and incorrect base pairs for wild type and R283A mutant

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Steady-state and pre-steady-state kinetic analysis of 8-oxo-7,8-dihydroguanosine triphosphate incorporation and extension by replicative and repair DNA polymerases

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Recognition of formamidopyrimidine by Escherichia coli and mammalian thymine glycol glycosylases. Distinctive paired base effects and biological and mechanistic implications.

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Distinct repair activities of human 7,8-dihydro-8-oxoguanine DNA glycosylase and formamidopyrimidine DNA glycosylase for formamidopyrimidine and 7,8-dihydro-8-oxoguanine

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The base catalysed anomerisation of beta-5-formyluridine; crystal and molecular structure of alpha-5-formyluridine

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Gel fidelity assay measuring nucleotide misinsertion, exonucleolytic proofreading, and lesion bypass efficiencies

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5-Formyldeoxyuridine: a new type of DNA damage induced by ionizing radiation and its mutagenicity to salmonella strain TA102.

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Measurement of Oxidative Damage at Pyrimidine Bases in γ-Irradiated DNA

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Formation of 5-formyl-2'-deoxycytidine from 5-methyl-2'-deoxycytidine in duplex DNA by Fenton-type reactions and gamma-irradiation

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Comparison of oxidation products from DNA components by gamma-irradiation and Fenton-type reactions.

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Peroxy radical oxidation of thymidine

1 reference

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Insertion of specific bases during DNA synthesis past the oxidation-damaged base 8-oxodG

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MutT protein specifically hydrolyses a potent mutagenic substrate for DNA synthesis

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Major oxidative products of cytosine, 5-hydroxycytosine and 5-hydroxyuracil, exhibit sequence context-dependent mispairing in vitro.

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Oxidized, deaminated cytosines are a source of C --> T transitions in vivo

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Conformation and proton configuration of pyrimidine deoxynucleoside oxidation damage products in water

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Ionized and wobble base-pairing for bromouracil-guanine in equilibrium under physiological conditions. A nuclear magnetic resonance study on an oligonucleotide containing a bromouracil-guanine base-pair as a function of pH.

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Mutagenic effects of 5-formyluracil on a plasmid vector during replication in Escherichia coli

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Synthesis of 5-Substituted Pyrimidines via Formaldehyde Addition¹

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19 October 2022

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Identifiers

10.1074/JBC.M008598200

1 reference

Europe PubMed Central

PubMed publication ID

24 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

24 November 2017

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