(Q43568416)

24 November 2017

Probing fibroblast growth factor dimerization and role of heparin-like glycosaminoglycans in modulating dimerization and signaling (English)

1 reference

24 November 2017

Kwan CP

1

1 reference

24 November 2017

Venkataraman G

2

1 reference

24 November 2017

Shriver Z

3

1 reference

24 November 2017

Raman R

4

1 reference

24 November 2017

Liu D

5

1 reference

24 November 2017

Qi Y

6

1 reference

24 November 2017

Varticovski L

7

1 reference

24 November 2017

Sasisekharan R

8

1 reference

24 November 2017

language of work or name

English

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publication date

5 April 2001

1 reference

Journal of Biological Chemistry

24 November 2017

1 reference

24 November 2017

276

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24 November 2017

26

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24 November 2017

23421-23429

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FGFs, heparan sulfate and FGFRs: complex interactions essential for development

24 November 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Structural characterization and biological functions of fibroblast growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Fibroblast growth factor-2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Fibroblast growth factor receptor tyrosine kinases: molecular analysis and signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Functions of fibroblast growth factors and their receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Regulation of growth factor activation by proteoglycans: what is the role of the low affinity receptors?

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Structure-activity relationship of heparan sulphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Heparan sulfate: decoding a dynamic multifunctional cell regulator

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Heparin and heparan sulfate: biosynthesis, structure and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Heparin structure and interactions with basic fibroblast growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

FGF binding and FGF receptor activation by synthetic heparan-derived di- and trisaccharides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Heparan sulfate mediates bFGF transport through basement membrane by diffusion with rapid reversible binding.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Heparin and heparan sulfate increase the radius of diffusion and action of basic fibroblast growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Fibroblast growth factor receptor signalling is dictated by specific heparan sulphate saccharides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Specificity for fibroblast growth factors determined by heparan sulfate in a binary complex with the receptor kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Heparan sulfate oligosaccharides require 6-O-sulfation for promotion of basic fibroblast growth factor mitogenic activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Heparin is required for cell-free binding of basic fibroblast growth factor to a soluble receptor and for mitogenesis in whole cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Heparin-induced oligomerization of FGF molecules is responsible for FGF receptor dimerization, activation, and cell proliferation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Preferential self-association of basic fibroblast growth factor is stabilized by heparin during receptor dimerization and activation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Oligomeric self-association of basic fibroblast growth factor in the absence of heparin-like glycosaminoglycans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Fibroblast growth factors 1 and 2 are distinct in oligomerization in the presence of heparin-like glycosaminoglycans

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Properly oriented heparin-decasaccharide-induced dimers are the biologically active form of basic fibroblast growth factor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Structure of a heparin-linked biologically active dimer of fibroblast growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Structural basis for FGF receptor dimerization and activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Structural interactions of fibroblast growth factor receptor with its ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Expression in Escherichia coli, purification and characterization of heparinase I from Flavobacterium heparinum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

High-resolution solution structure of basic fibroblast growth factor determined by multidimensional heteronuclear magnetic resonance spectroscopy

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Three-dimensional structure of human basic fibroblast growth factor, a structural homolog of interleukin 1 beta

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Refinement of the structure of human basic fibroblast growth factor at 1.6 A resolution and analysis of presumed heparin binding sites by selenate substitution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

The formation of a disulfide cross-link between the two subunits demonstrates the dimeric structure of the mitochondrial oxoglutarate carrier

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Molecular characteristics of fibroblast growth factor-fibroblast growth factor receptor-heparin-like glycosaminoglycan complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Dimerization of cell surface receptors in signal transduction

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Receptor signaling: when dimerization is not enough

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

An antagonist peptide-EPO receptor complex suggests that receptor dimerization is not sufficient for activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Crystallographic evidence for dimerization of unliganded tumor necrosis factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Structures of the extracellular domain of the type I tumor necrosis factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Monomer complexes of basic fibroblast growth factor and heparan sulfate oligosaccharides are the minimal functional unit for cell activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

An essential heparin-binding domain in the fibroblast growth factor receptor kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Heparin-induced self-association of fibroblast growth factor-2. Evidence for two oligomerization processes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

Multivalent Ligand-Receptor Binding Interactions in the Fibroblast Growth Factor System Produce a Cooperative Growth Factor and Heparin Mechanism for Receptor Dimerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M010786200

21 January 2018

Identifiers

DOI

10.1074/JBC.M010786200

1 reference

24 November 2017

1 reference