(Q43579801)

24 November 2017

LGR5 deficiency deregulates Wnt signaling and leads to precocious Paneth cell differentiation in the fetal intestine (English)

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24 November 2017

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Marie Isabelle Garcia

1

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24 November 2017

Mariangela Ghiani

2

1 reference

24 November 2017

Anne Lefort

3

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24 November 2017

Frédérick Libert

4

1 reference

24 November 2017

Sandra Strollo

5

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24 November 2017

Gilbert Vassart

6

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24 November 2017

language of work or name

English

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publication date

24 April 2009

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24 November 2017

10

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based on heuristic

inferred from page(s)

published in

Developmental Biology

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24 November 2017

331

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24 November 2017

58-67

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24 November 2017

1

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Crypt-restricted proliferation and commitment to the Paneth cell lineage following Apc loss in the mouse intestine.

24 November 2017

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

A genetic study of the role of the Wnt/beta-catenin signalling in Paneth cell differentiation.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Identification of stem cells in small intestine and colon by marker gene Lgr5

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Self-renewal, multipotency, and the existence of two cell populations within an epithelial stem cell niche

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Paneth cell differentiation in the developing intestine of normal and transgenic mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

A novel modulatory mechanism of transforming growth factor-beta signaling through decorin and LRP-1.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Origin, differentiation and renewal of the four main epithelial cell types in the mouse small intestine. I. Columnar cell.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Delta-Notch signalling controls commitment to a secretory fate in the zebrafish intestine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Organizing cell renewal in the intestine: stem cells, signals and combinatorial control

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Notch signals control the fate of immature progenitor cells in the intestine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

NOV (CCN3) functions as a regulator of human hematopoietic stem or progenitor cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Intestinal polyposis in mice with a dominant stable mutation of the beta-catenin gene

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Hesr1 and Hesr2 may act as early effectors of Notch signaling in the developing cochlea

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Characterization of two LGR genes homologous to gonadotropin and thyrotropin receptors with extracellular leucine-rich repeats and a G protein-coupled, seven-transmembrane region

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Postnatal changes in the expression of genes for cryptdins 1-6 and the role of luminal bacteria in cryptdin gene expression in mouse small intestine.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Achaete-scute like 2 (ascl2) is a target of Wnt signalling and is upregulated in intestinal neoplasia

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

The Hes gene family: repressors and oscillators that orchestrate embryogenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

A critical role for elastin signaling in vascular morphogenesis and disease

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Phases of canonical Wnt signaling during the development of mouse intestinal epithelium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

The intestinal epithelial stem cell

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Defective postnatal development of the male reproductive tract in LGR4 knockout mice

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Cell-specific expression of alpha 1-antitrypsin in human intestinal epithelium

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Neonatal lethality of LGR5 null mice is associated with ankyloglossia and gastrointestinal distension

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Capturing and profiling adult hair follicle stem cells.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Innate defenses of the intestinal epithelial barrier

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Multipotent Drosophila intestinal stem cells specify daughter cell fates by differential notch signaling.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Wnt, stem cells and cancer in the intestine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Loss of intestinal crypt progenitor cells owing to inactivation of both Notch1 and Notch2 is accompanied by derepression of CDK inhibitors p27Kip1 and p57Kip2.

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

The "normal" endocrine cell of the gut: changing concepts and new evidences

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

The nephroblastoma overexpressed gene (NOV/ccn3) protein associates with Notch1 extracellular domain and inhibits myoblast differentiation via Notch signaling pathway

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Bmi1 is expressed in vivo in intestinal stem cells

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Single Lgr5 stem cells build crypt-villus structures in vitro without a mesenchymal niche

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Current view: intestinal stem cells and signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Vascular abnormalities in mice lacking the endothelial gap junction proteins connexin37 and connexin40

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Hes1-deficient mice show precocious differentiation of Paneth cells in the small intestine

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Dietary zinc deficiency and repletion modulate metallothionein immunolocalization and concentration in small intestine and liver of rats

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Significance analysis of microarrays applied to the ionizing radiation response

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Transcription factor achaete scute-like 2 controls intestinal stem cell fate

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Wnt signalling induces maturation of Paneth cells in intestinal crypts

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Matrix metalloproteinase-7 activation of mouse paneth cell pro-alpha-defensins: SER43 down arrow ILE44 proteolysis enables membrane-disruptive activity

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Selection of multipotent stem cells during morphogenesis of small intestinal crypts of Lieberkuhn is perturbed by stimulation of Lef-1/beta-catenin signaling

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Elevated expression of axin2 and hnkd mRNA provides evidence that Wnt/beta -catenin signaling is activated in human colon tumors

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

Deletion of the WNT Target and Cancer Stem Cell Marker CD44 in Apc(Min/+) Mice Attenuates Intestinal Tumorigenesis

7 January 2021

1 reference

https://api.crossref.org/works/10.1016%2FJ.YDBIO.2009.04.020

10.1016/J.YDBIO.2009.04.020

7 January 2021

Identifiers

DOI

1 reference

24 November 2017

1 reference