(Q43583211)

English

Sphingosine generation, cytochrome c release, and activation of caspase-7 in doxorubicin-induced apoptosis of MCF7 breast adenocarcinoma cells.

scientific article published in February 2001

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11313718%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Sphingosine generation, cytochrome c release, and activation of caspase-7 in doxorubicin-induced apoptosis of MCF7 breast adenocarcinoma cells (English)

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11313718%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

1 reference

based on heuristic

inferred from title

breast adenocarcinoma

1 reference

based on heuristic

inferred from title

Olivier Cuvillier

1

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11313718%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

author name string

Nava VE

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11313718%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Murthy SK

3

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11313718%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Edsall LC

4

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11313718%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Levade T

5

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11313718%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Milstien S

6

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11313718%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Spiegel S

7

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11313718%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

publication date

1 February 2001

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11313718%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Cell Death & Differentiation

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11313718%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

8

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11313718%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

2

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11313718%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

162-171

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11313718%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunorubicin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Ceramide in the eukaryotic stress response

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Daunorubicin-induced apoptosis: triggering of ceramide generation through sphingomyelin hydrolysis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Influence of Bcl-2 overexpression on the ceramide pathway in daunorubicin-induced apoptosis of leukemic cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Serine protease inhibitors block neutral sphingomyelinase activation, ceramide generation, and apoptosis triggered by daunorubicin

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Alteration of the daunorubicin-triggered sphingomyelin-ceramide pathway and apoptosis in MDR cells: influence of drug transport abnormalities.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Daunorubicin- and mitoxantrone-triggered phosphatidylcholine hydrolysis: implication in drug-induced ceramide generation and apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

L-carnitine prevents doxorubicin-induced apoptosis of cardiac myocytes: role of inhibition of ceramide generation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Doxorubicin induces slow ceramide accumulation and late apoptosis in cultured adult rat ventricular myocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

A possible role of sphingosine in induction of apoptosis by tumor necrosis factor-alpha in human neutrophils

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Tumor necrosis factor alpha-induced apoptosis in cardiac myocytes. Involvement of the sphingolipid signaling cascade in cardiac cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Sphingosine and its methylated derivative N,N-dimethylsphingosine (DMS) induce apoptosis in a variety of human cancer cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Inhibition of sphingolipid induced apoptosis by caspase inhibitors indicates that sphingosine acts in an earlier part of the apoptotic pathway than ceramide

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Induction of apoptosis and potentiation of ceramide-mediated cytotoxicity by sphingoid bases in human myeloid leukemia cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Involvement of sphingosine in mitochondria-dependent Fas-induced apoptosis of type II Jurkat T cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Changing J774A.1 cells to new medium perturbs multiple signaling pathways, including the modulation of protein kinase C by endogenous sphingoid bases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Differential Roles of de Novo Sphingolipid Biosynthesis and Turnover in the “Burst” of Free Sphingosine and Sphinganine, and Their 1-Phosphates and N-Acyl-Derivatives, That Occurs upon Changing the Medium of Cells in Culture

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Sphingosine induces apoptosis in androgen-independent human prostatic carcinoma DU-145 cells by suppression of bcl-X(L) gene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

(1S,2R)-D-erythro-2-(N-myristoylamino)-1-phenyl-1-propanol as an inhibitor of ceramidase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Bcl-2 interrupts the ceramide-mediated pathway of cell death.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Ceramides induce a form of apoptosis in human acute lymphoblastic leukemia cells that is inhibited by Bcl-2, but not by CrmA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

prICE: a downstream target for ceramide-induced apoptosis and for the inhibitory action of Bcl-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Cytokine response modifier A (CrmA) inhibits ceramide formation in response to tumor necrosis factor (TNF)-alpha: CrmA and Bcl-2 target distinct components in the apoptotic pathway

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Apoptosis of lung cancer cells caused by some anti-cancer agents (MMC, CPT-11, ADM) is inhibited by bcl-2.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

A functional role for mitochondrial protein kinase Calpha in Bcl2 phosphorylation and suppression of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

BCL-2 expression does not not correlate with patient outcome in pediatric acute myelogenous leukemia

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Caspase structure, proteolytic substrates, and function during apoptotic cell death

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Bcl-xL functions downstream of caspase-8 to inhibit Fas- and tumor necrosis factor receptor 1-induced apoptosis of MCF7 breast carcinoma cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell-specific induction of apoptosis by microinjection of cytochrome c. Bcl-xL has activity independent of cytochrome c release

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Bcl-xL acts downstream of caspase-8 activation by the CD95 death-inducing signaling complex.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Apaf1 and the apoptotic machinery

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Serial killers: ordering caspase activation events in apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Biochemical pathways of caspase activation during apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Caspase-3 is the primary activator of apoptotic DNA fragmentation via DNA fragmentation factor-45/inhibitor of caspase-activated DNase inactivation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Importance of the redox state of cytochrome c during caspase activation in cytosolic extracts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of CD95 (APO-1/Fas) signaling by ceramide mediates cancer therapy-induced apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Deficient activation of the CD95 (APO-1/Fas) system in drug-resistant cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Activation of the CD95 (APO-1/Fas) pathway in drug- and gamma-irradiation-induced apoptosis of brain tumor cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Mechanisms of CD95 (APO-1/Fas)-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Accumulation of glucosylceramides in multidrug-resistant cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Expression of glucosylceramide synthase, converting ceramide to glucosylceramide, confers adriamycin resistance in human breast cancer cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Uncoupling ceramide glycosylation by transfection of glucosylceramide synthase antisense reverses adriamycin resistance

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Sphingomyelin potentiates chemotherapy of human cancer xenografts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Partial Inhibition of Multidrug Resistance by Safingol Is Independent of Modulation of P-glycoprotein Substrate Activities and Correlated with Inhibition of Protein Kinase C

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Caspase-3 is required for alpha-fodrin cleavage but dispensable for cleavage of other death substrates in apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Sphingosine kinase from Swiss 3T3 fibroblasts: a convenient assay for the measurement of intracellular levels of free sphingoid bases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Involvement of sphingosine 1-phosphate in nerve growth factor-mediated neuronal survival and differentiation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Inorganic and organic phosphate measurements in the nanomolar range

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Suppression of ceramide-mediated programmed cell death by sphingosine-1-phosphate

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Sphingosine 1-phosphate inhibits activation of caspases that cleave poly(ADP-ribose) polymerase and lamins during Fas- and ceramide-mediated apoptosis in Jurkat T lymphocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CDD.4400793

7 January 2021

based on heuristic

inferred from DOI database lookup

Identifiers

10.1038/SJ.CDD.4400793

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11313718%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11313718%20AND%20SRC:MED&resulttype=core&format=json

6 November 2019

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q43583211&oldid=2206140649"