(Q43583320)

English

Regulation of estrogenic and nuclear factor kappa B functions by polyamines and their role in polyamine analog-induced apoptosis of breast cancer cells

scientific article published in March 2001

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scholarly article

1 reference

Europe PubMed Central

24 November 2017

Regulation of estrogenic and nuclear factor kappa B functions by polyamines and their role in polyamine analog-induced apoptosis of breast cancer cells (English)

1 reference

Europe PubMed Central

24 November 2017

N(1),N(12)-diethylspermine

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ChEBI release 2020-05-28

Carolyn M. Klinge

4

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Europe PubMed Central

24 November 2017

author name string

Shah N

1

1 reference

Europe PubMed Central

24 November 2017

Thomas TJ

2

1 reference

Europe PubMed Central

24 November 2017

Lewis JS

3

1 reference

Europe PubMed Central

24 November 2017

Shirahata A

5

1 reference

Europe PubMed Central

24 November 2017

Gelinas C

6

1 reference

Europe PubMed Central

24 November 2017

Thomas T

7

1 reference

Europe PubMed Central

24 November 2017

language of work or name

0 references

publication date

1 March 2001

1 reference

Europe PubMed Central

24 November 2017

1 reference

Europe PubMed Central

24 November 2017

20

1 reference

Europe PubMed Central

24 November 2017

1715-1729

1 reference

Europe PubMed Central

24 November 2017

14

1 reference

Europe PubMed Central

24 November 2017

https://scigraph.springernature.com/pub.10.1038/sj.onc.1204247

0 references

The NF-kappa B and I kappa B proteins: new discoveries and insights

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NF-kappa B: ten years after

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An essential role for NF-kappaB in preventing TNF-alpha-induced cell death

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Inhibition of cell growth in CaCO2 cells by the polyamine analogue N1,N12-bis(ethyl)spermine is preceded by a reduction in MYC oncoprotein levels

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Gene activation by histone and factor acetyltransferases

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Phenol red in tissue culture media is a weak estrogen: implications concerning the study of estrogen-responsive cells in culture

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Epidermal growth factor-induced nuclear factor kappa B activation: A major pathway of cell-cycle progression in estrogen-receptor negative breast cancer cells

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Ceramide activates NFkappaB by inducing the processing of p105.

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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Elevated cellular polyamine levels enhance promoter activity in vivo

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Suppression of tumor necrosis factor-induced cell death by inhibitor of apoptosis c-IAP2 is under NF-kappaB control

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Clinical aspects of cell death in breast cancer: the polyamine pathway as a new target for treatment

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Influence of polyamines on DNA binding of heat shock and activator protein 1 transcription factors induced by heat shock.

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Mechanisms of transcriptional activation of bcl-2 gene expression by 17beta-estradiol in breast cancer cells

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Molecular mechanics of the interactions of spermine with DNA: DNA bending as a result of ligand binding

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Estrogen receptor impairs interleukin-6 expression by preventing protein binding on the NF-kappaB site

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CREB-binding protein/p300 are transcriptional coactivators of p65

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Rel-dependent induction of A1 transcription is required to protect B cells from antigen receptor ligation-induced apoptosis

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NF-kappaB controls cell growth and differentiation through transcriptional regulation of cyclin D1.

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The role of polyamine catabolism in polyamine analogue-induced programmed cell death

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p300 is a component of an estrogen receptor coactivator complex

1 reference

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Regulation of RelA subcellular localization by a putative nuclear export signal and p50.

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NF-kappaB function in growth control: regulation of cyclin D1 expression and G0/G1-to-S-phase transition

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Rapid induction of apoptosis by deregulated uptake of polyamine analogues

1 reference

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Polyamines: mysterious modulators of cellular functions

1 reference

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Adaptor-mediated recruitment of RNA polymerase II to a signal-dependent activator

1 reference

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Roles of histone acetyltransferases and deacetylases in gene regulation

1 reference

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21 January 2018

Characterization of mechanisms of interleukin-6 gene repression by estrogen receptor.

1 reference

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21 January 2018

Involvement of the polyamine pathway in breast cancer progression.

1 reference

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Phosphorylation of p105 PEST sequence via a redox-insensitive pathway up-regulates processing of p50 NF-kappaB.

1 reference

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21 January 2018

Polyamines as targets for therapeutic intervention

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Hypoxia-induced endothelial apoptosis through nuclear factor-kappaB (NF-kappaB)-mediated bcl-2 suppression: in vivo evidence of the importance of NF-kappaB in endothelial cell regulation

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Requirement of NF-kappaB activation to suppress p53-independent apoptosis induced by oncogenic Ras.

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Constitutive activation of NF-kappaB during progression of breast cancer to hormone-independent growth

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Precursors of colorectal carcinoma. Biopsy and biologic markers

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The transcriptional coactivators p300 and CBP are histone acetyltransferases

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Polyamines alter sequence-specific DNA-protein interactions

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Polyamine metabolism and function

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Combined regulation of ornithine and S-adenosylmethionine decarboxylases by spermine and the spermine analogue N1 N12-bis(ethyl)spermine

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Aberrant rel/nfkb genes and activity in human cancer

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Role of NF-κB in p53-mediated programmed cell death

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Polyamines and mammalian hormones Part II: Paracrine signals and intracellular regulators

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Bcl-2 gene family and related proteins in mammary gland involution and breast cancer

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Activation of nuclear factor kappaB by polyamines in breast cancer cells

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Transcriptional activation by NF-kappaB requires multiple coactivators

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Aberrant nuclear factor-kappaB/Rel expression and the pathogenesis of breast cancer

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Structure, regulation and function of NF-kappa B

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Co-operation between follicular ornithine decarboxylase and v-Ha-ras induces spontaneous papillomas and malignant conversion in transgenic skin

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Repression of the interleukin-6 promoter by estrogen receptor is mediated by NF-kappa B and C/EBP beta

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Activation of the proto-oncogene c-myc and c-fos by c-ras: involvement of polyamines

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Role of polyamines in mediating malignant transformation and oncogene expression

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Induction of p21 (CIP1/WAF1/SID1) by estradiol in a breast epithelial cell line transfected with the recombinant estrogen receptor gene: a possible mechanism for a negative regulatory role of estradiol

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Polyamine-mediated conformational perturbations in DNA alter the binding of estrogen receptor to poly(dG-m5dC).poly(dG-m5dC) and a plasmid containing the estrogen response element

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Effects of natural and synthetic polyamines on the conformation of an oligodeoxyribonucleotide with the estrogen response element

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Estradiol control of ornithine decarboxylase mRNA, enzyme activity, and polyamine levels in MCF-7 breast cancer cells: therapeutic implications

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Polyamines in cell growth and cell death: molecular mechanisms and therapeutic applications

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The nuclear factor-kappaB engages CBP/p300 and histone acetyltransferase activity for transcriptional activation of the interleukin-6 gene promoter.

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CREB-binding protein is a nuclear integrator of nuclear factor-kappaB and p53 signaling

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TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaB

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Phosphorylation of NF-kappa B p65 by PKA stimulates transcriptional activity by promoting a novel bivalent interaction with the coactivator CBP/p300

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Caveolin-1 Potentiates Estrogen Receptor α (ERα) Signaling

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Dynamic shuttling of nuclear factor kappa B between the nucleus and cytoplasm as a consequence of inhibitor dissociation

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1 reference

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1 reference

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Molecular correlates of the action of bis(ethyl)polyamines in breast cancer cell growth inhibition and apoptosis

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Regulation of NF-kappa B activity by I kappa B alpha and I kappa B beta stability

1 reference

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1 reference

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1 reference

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1 reference

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7 January 2021

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1 reference

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1 reference

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7 January 2021

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Polyamine biosynthesis inhibitors alter protein-protein interactions involving estrogen receptor in MCF-7 breast cancer cells

1 reference

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7 January 2021

based on heuristic

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1 reference

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Identifiers

10.1038/SJ.ONC.1204247

1 reference

Europe PubMed Central

24 November 2017

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1 reference

Europe PubMed Central

24 November 2017

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