(Q43594596)

25 November 2017

ERK induces p35, a neuron-specific activator of Cdk5, through induction of Egr1. (English)

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25 November 2017

T Harada

1

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25 November 2017

T Morooka

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2

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25 November 2017

S Ogawa

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3

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25 November 2017

E Nishida

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4

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25 November 2017

1 May 2001

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25 November 2017

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25 November 2017

3

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25 November 2017

453-459

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25 November 2017

5

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https://scigraph.springernature.com/pub.10.1038/35074516

25 November 2017

0 references

cites work

Recent progress in characterization of protein kinase cascades for phosphorylation of ribosomal protein S6.

1 reference

7 January 2021

The mitogen-activated protein kinase activator

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7 January 2021

The MAP kinase cascade is essential for diverse signal transduction pathways

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7 January 2021

The regulation of AP-1 activity by mitogen-activated protein kinases

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7 January 2021

Mitogen-activated protein kinase pathways

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7 January 2021

Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor

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7 January 2021

Specificity of receptor tyrosine kinase signaling: transient versus sustained extracellular signal-regulated kinase activation

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7 January 2021

Microtubule-associated-protein (MAP) kinase activated by nerve growth factor and epidermal growth factor in PC12 cells. Identity with the mitogen-activated MAP kinase of fibroblastic cells

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7 January 2021

ERKs: a family of protein-serine/threonine kinases that are activated and tyrosine phosphorylated in response to insulin and NGF

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7 January 2021

Sustained activation of the mitogen-activated protein (MAP) kinase cascade may be required for differentiation of PC12 cells. Comparison of the effects of nerve growth factor and epidermal growth factor

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7 January 2021

Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

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7 January 2021

Inhibition of MAP Kinase Kinase Blocks the Differentiation of PC-12 Cells Induced by Nerve Growth Factor

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7 January 2021

Identification of the 23 kDa subunit of tau protein kinase II as a putative activator of cdk5 in bovine brain.

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7 January 2021

p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5

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7 January 2021

A brain-specific activator of cyclin-dependent kinase 5.

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7 January 2021

The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation

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7 January 2021

Role of cyclins in neuronal differentiation of immortalized hippocampal cells

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7 January 2021

Evidence for the participation of the neuron-specific CDK5 activator P35 during laminin-enhanced axonal growth.

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7 January 2021

Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death

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7 January 2021

Mice lacking p35, a neuronal specific activator of Cdk5, display cortical lamination defects, seizures, and adult lethality

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7 January 2021

Neuronal cdc2-like kinase

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7 January 2021

Tau in Alzheimer's disease.

1 reference

7 January 2021

Biochemical and cellular effects of roscovitine, a potent and selective inhibitor of the cyclin-dependent kinases cdc2, cdk2 and cdk5.

1 reference

7 January 2021

PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

1 reference

7 January 2021

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

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7 January 2021

A novel regulatory mechanism in the mitogen-activated protein (MAP) kinase cascade. Role of nuclear export signal of MAP kinase kinase.

1 reference

7 January 2021

Identification of a novel inhibitor of mitogen-activated protein kinase kinase

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7 January 2021

Molecular cloning and chromosomal mapping of the mouse gene encoding cyclin-dependent kinase 5 regulatory subunit p35.

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7 January 2021

A nerve growth factor-induced gene encodes a possible transcriptional regulatory factor.

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7 January 2021

The EGR family of transcription-regulatory factors: progress at the interface of molecular and systems neuroscience.

1 reference

7 January 2021

Growth hormone stimulates phosphorylation and activation of elk-1 and expression of c-fos, egr-1, and junB through activation of extracellular signal-regulated kinases 1 and 2.

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7 January 2021

NAB2, a corepressor of NGFI-A (Egr-1) and Krox20, is induced by proliferative and differentiative stimuli

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7 January 2021

The transcriptional corepressor NAB2 inhibits NGF-induced differentiation of PC12 cells

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7 January 2021

Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

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7 January 2021

MEK1 protein kinase inhibition protects against damage resulting from focal cerebral ischemia

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7 January 2021

Induction of an immediate early gene egr-1 by zinc through extracellular signal-regulated kinase activation in cortical culture: its role in zinc-induced neuronal death

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7 January 2021

Expression of cyclin-dependent kinase 5 and its activator p35 in rat brain after middle cerebral artery occlusion.

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7 January 2021

Activation of mitogen-activated protein kinases after transient forebrain ischemia in gerbil hippocampus

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7 January 2021

NGF regulates the PC12 cell cycle machinery through specific inhibition of the Cdk kinases and induction of cyclin D1

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7 January 2021

Requirement of p38 mitogen-activated protein kinase for neuronal differentiation in PC12 cells

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7 January 2021

Protein kinase Cdelta mediates neurogenic but not mitogenic activation of mitogen-activated protein kinase in neuronal cells

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7 January 2021

Membrane targeting of p21-activated kinase 1 (PAK1) induces neurite outgrowth from PC12 cells

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7 January 2021

Differential regulation of c-Jun by ERK and JNK during PC12 cell differentiation.

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7 January 2021

Two co-existing mechanisms for nuclear import of MAP kinase: passive diffusion of a monomer and active transport of a dimer.

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7 January 2021

Identifiers

DOI

10.1038/35074516

1 reference

25 November 2017

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