(Q43595338)

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Neuroprotective efficacy and pharmacokinetic behavior of novel anti-inflammatory para-phenyl substituted diindolylmethanes in a mouse model of Parkinson's disease.

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23318470%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Neuroprotective efficacy and pharmacokinetic behavior of novel anti-inflammatory para-phenyl substituted diindolylmethanes in a mouse model of Parkinson's disease (English)

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23318470%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

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pharmacokinetics

1 reference

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Briana R De Miranda

1

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23318470%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

James A Miller

2

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23318470%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Ryan J Hansen

3

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23318470%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Paul J Lunghofer

4

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23318470%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Stephen Safe

5

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23318470%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Daniel L Gustafson

6

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23318470%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Dorothy Colagiovanni

7

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23318470%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

Ronald B Tjalkens

8

1 reference

Europe PubMed Central

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22 February 2020

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14 January 2013

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22 February 2020

Journal of Pharmacology and Experimental Therapeutics

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23318470%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

345

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23318470%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

1

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23318470%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

125-138

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23318470%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

In vitro glucuronidation using human liver microsomes and the pore-forming peptide alamethicin.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23318470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The parkinsonian toxin MPTP: action and mechanism.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23318470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A new class of peroxisome proliferator-activated receptor gamma (PPARgamma) agonists that inhibit growth of breast cancer cells: 1,1-Bis(3'-indolyl)-1-(p-substituted phenyl)methanes.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23318470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Physiological modeling of formulated and crystalline 3,3'-diindolylmethane pharmacokinetics following oral administration in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23318470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In vivo pattern of lipopolysaccharide and anti-CD3-induced NF-kappa B activation using a novel gene-targeted enhanced GFP reporter gene mouse

1 reference

https://pubmed.ncbi.nlm.nih.gov/23318470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Parkin-deficient mice are not a robust model of parkinsonism

1 reference

https://pubmed.ncbi.nlm.nih.gov/23318470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The inhibition of beta-glucuronidase by saccharic acid and the role of the enzyme in glucuronide synthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23318470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetics and absolute bioavailability of selegiline following treatment of healthy subjects with the selegiline transdermal system (6 mg/24 h): a comparison with oral selegiline capsules

1 reference

https://pubmed.ncbi.nlm.nih.gov/23318470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

In silico and in vitro pharmacogenetic analysis in mice

1 reference

https://pubmed.ncbi.nlm.nih.gov/23318470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The peroxisome proliferator-activated receptor-gamma agonist 1,1-bis(3'-indolyl)-1-(p-trifluoromethylphenyl)methane suppresses manganese-induced production of nitric oxide in astrocytes and inhibits apoptosis in cocultured PC12 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23318470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cancer chemotherapy with indole-3-carbinol, bis(3'-indolyl)methane and synthetic analogs

1 reference

https://pubmed.ncbi.nlm.nih.gov/23318470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Modeling PD pathogenesis in mice: advantages of a chronic MPTP protocol

1 reference

https://pubmed.ncbi.nlm.nih.gov/23318470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suppression of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced nitric-oxide synthase 2 expression in astrocytes by a novel diindolylmethane analog protects striatal neurons against apoptosis

1 reference

https://pubmed.ncbi.nlm.nih.gov/23318470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Striatal plasticity and basal ganglia circuit function

1 reference

https://pubmed.ncbi.nlm.nih.gov/23318470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

1,1-Bis(3'-indolyl)-1-(p-chlorophenyl)methane activates the orphan nuclear receptor Nurr1 and inhibits bladder cancer growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/23318470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglia protect neurons against ischemia by synthesis of tumor necrosis factor.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23318470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

PPAR-gamma-mediated neuroprotection in a chronic mouse model of Parkinson's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/23318470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Neuroinflammation in Parkinson's disease: a target for neuroprotection?

1 reference

https://pubmed.ncbi.nlm.nih.gov/23318470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A Nurr1/CoREST pathway in microglia and astrocytes protects dopaminergic neurons from inflammation-induced death

1 reference

https://pubmed.ncbi.nlm.nih.gov/23318470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Astrocytic dysfunction: insights on the role in neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/23318470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inflammatory neurodegeneration and mechanisms of microglial killing of neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/23318470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Mechanisms underlying inflammation in neurodegeneration

1 reference

https://pubmed.ncbi.nlm.nih.gov/23318470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Microglia and neuroprotection: from in vitro studies to therapeutic applications

1 reference

https://pubmed.ncbi.nlm.nih.gov/23318470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Inactivation of the orphan nuclear receptor TR3/Nur77 inhibits pancreatic cancer cell and tumor growth

1 reference

https://pubmed.ncbi.nlm.nih.gov/23318470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Targeting NR4A1 (TR3) in cancer cells and tumors

1 reference

https://pubmed.ncbi.nlm.nih.gov/23318470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Low-dose 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine causes inflammatory activation of astrocytes in nuclear factor-κB reporter mice prior to loss of dopaminergic neurons.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23318470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Rosiglitazone decreases peroxisome proliferator receptor-γ levels in microglia and inhibits TNF-α production: new evidences on neuroprotection in a progressive Parkinson's disease model.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23318470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The nuclear receptor TR3 regulates mTORC1 signaling in lung cancer cells expressing wild-type p53.

1 reference

https://pubmed.ncbi.nlm.nih.gov/23318470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Structure-dependent activation of NR4A2 (Nurr1) by 1,1-bis(3'-indolyl)-1-(aromatic)methane analogs in pancreatic cancer cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/23318470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Unbiased stereological estimation of the number of neurons in the human hippocampus

1 reference

https://pubmed.ncbi.nlm.nih.gov/23318470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of age on the pharmacokinetics of levodopa administered alone and in the presence of carbidopa

1 reference

https://pubmed.ncbi.nlm.nih.gov/23318470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neurons

1 reference

https://pubmed.ncbi.nlm.nih.gov/23318470

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1124/JPET.112.201558

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23318470%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23318470%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23318470%20AND%20SRC:MED&resulttype=core&format=json

22 February 2020

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