(Q43619021)

English

The catalytic and GAF domains of the rod cGMP phosphodiesterase (PDE6) heterodimer are regulated by distinct regions of its inhibitory gamma subunit

scientific article published on 24 May 2001

In more languages

Statements

scholarly article

1 reference

Europe PubMed Central

25 November 2017

The catalytic and GAF domains of the rod cGMP phosphodiesterase (PDE6) heterodimer are regulated by distinct regions of its inhibitory gamma subunit (English)

1 reference

Europe PubMed Central

25 November 2017

author name string

H Mou

1

1 reference

Europe PubMed Central

25 November 2017

R H Cote

2

1 reference

Europe PubMed Central

25 November 2017

language of work or name

0 references

publication date

24 May 2001

1 reference

Europe PubMed Central

25 November 2017

Journal of Biological Chemistry

1 reference

Europe PubMed Central

25 November 2017

276

1 reference

Europe PubMed Central

25 November 2017

29

1 reference

Europe PubMed Central

25 November 2017

27527-27534

1 reference

Europe PubMed Central

25 November 2017

Interactions of a G-protein with its effector: transducin and cGMP phosphodiesterase in retinal rods

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Amplification and kinetics of the activation steps in phototransduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Reciprocal control of retinal rod cyclic GMP phosphodiesterase by its gamma subunit and transducin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Affinities of bovine photoreceptor cGMP phosphodiesterases for rod and cone inhibitory subunits.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

The carboxyl terminus of the gamma-subunit of rod cGMP phosphodiesterase contains distinct sites of interaction with the enzyme catalytic subunits and the alpha-subunit of transducin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Interaction between the retinal cyclic GMP phosphodiesterase inhibitor and transducin. Kinetics and affinity studies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Delineation of two functionally distinct gammaPDE binding sites on the bovine retinal cGMP phosphodiesterase by a mutant gammaPDE subunit

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Functional regions of the inhibitory subunit of retinal rod cGMP phosphodiesterase identified by site-specific mutagenesis and fluorescence spectroscopy

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Two-site high-affinity interaction between inhibitory and catalytic subunits of rod cyclic GMP phosphodiesterase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Domain mapping of the retinal cyclic GMP phosphodiesterase γ-subunit. Function of the domains encoded by the three exons of the γ-subunit gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

An interface of interaction between photoreceptor cGMP phosphodiesterase catalytic subunits and inhibitory gamma subunits.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

An effector site that stimulates G-protein GTPase in photoreceptors.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Structural determinants for regulation of phosphodiesterase by a G protein at 2.0 A

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

cGMP binding to noncatalytic sites on mammalian rod photoreceptor phosphodiesterase is regulated by binding of its gamma and delta subunits

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Measurement of protein using bicinchoninic acid

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Regulation of photoreceptor phosphodiesterase catalysis by its non-catalytic cGMP-binding sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Activation of cGMP phosphodiesterase in retinal rods: mechanism of interaction with the GTP-binding protein (transducin).

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Activation of phosphodiesterase by transducin in bovine rod outer segments: characteristics of the successive binding of two transducins.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Heterozygous missense mutation in the rod cGMP phosphodiesterase beta-subunit gene in autosomal dominant stationary night blindness

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Retinal degeneration in mice lacking the gamma subunit of the rod cGMP phosphodiesterase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Rod photoreceptor cGMP-phosphodiesterase: analysis of alpha and beta subunits expressed in human kidney cells

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Probing domain functions of chimeric PDE6alpha'/PDE5 cGMP-phosphodiesterase.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

The GAF domain: an evolutionary link between diverse phototransducing proteins.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

The catalytic subunit of protein kinase A triggers activation of the type V cyclic GMP-specific phosphodiesterase from guinea-pig lung

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Phosphorylation of the gamma subunit of the retinal photoreceptor cGMP phosphodiesterase by the cAMP-dependent protein kinase and its effect on the gamma subunit interaction with other proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Phosphorylation by cyclin-dependent protein kinase 5 of the regulatory subunit of retinal cGMP phosphodiesterase. I. Identification of the kinase and its role in the turnoff of phosphodiesterase in vitro

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Residues within the polycationic region of cGMP phosphodiesterase gamma subunit crucial for the interaction with transducin alpha subunit. Identification by endogenous ADP-ribosylation and site-directed mutagenesis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Onset of feedback reactions underlying vertebrate rod photoreceptor light adaptation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

RGS9, a GTPase accelerator for phototransduction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Structure of the GAF domain, a ubiquitous signaling motif and a new class of cyclic GMP receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Atomic structure of PDE4: insights into phosphodiesterase mechanism and specificity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Regulation of deactivation of photoreceptor G protein by its target enzyme and cGMP

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Photoreceptor phosphodiesterase: interaction of inhibitory gamma subunit and cyclic GMP with specific binding sites on catalytic subunits

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Discrimination of two functions of photoreceptor cGMP phosphodiesterase gamma subunit

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Enhancement of phototransduction protein interactions by lipid surfaces

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Mechanism of transducin activation of frog rod photoreceptor phosphodiesterase. Allosteric interactiona between the inhibitory gamma subunit and the noncatalytic cGMP-binding sites

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Active sites of the cyclic GMP phosphodiesterase gamma-subunit of retinal rod outer segments

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

The gamma subunit of rod cGMP-phosphodiesterase blocks the enzyme catalytic site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Site-directed mutagenesis of the cGMP phosphodiesterase gamma subunit from bovine rod outer segments: role of separate amino acid residues in the interaction with catalytic subunits and transducin alpha subunit

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Role for the target enzyme in deactivation of photoreceptor G protein in vivo

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Mapping of effector binding sites of transducin alpha-subunit using G alpha t/G alpha i1 chimeras

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Kinetics and regulation of cGMP binding to noncatalytic binding sites on photoreceptor phosphodiesterase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

High affinity interactions of GTPgammaS with the heterotrimeric G protein, transducin. Evidence at high and low protein concentrations

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Structural features of the noncatalytic cGMP binding sites of frog photoreceptor phosphodiesterase using cGMP analogs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Phosphorylation of phosphodiesterase-5 by cyclic nucleotide-dependent protein kinase alters its catalytic and allosteric cGMP-binding activities

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Possible stimulation of retinal rod recovery to dark state by cGMP release from a cGMP phosphodiesterase noncatalytic site

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Identification of the gamma subunit-interacting residues on photoreceptor cGMP phosphodiesterase, PDE6alpha '

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103316200

21 January 2018

Identifiers

10.1074/JBC.M103316200

1 reference

Europe PubMed Central

25 November 2017

1 reference

Europe PubMed Central

25 November 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

Wikibooks(0 entries)

Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

Wiktionary(0 entries)

Multilingual sites(0 entries)

Retrieved from "https://www.wikidata.org/w/index.php?title=Q43619021&oldid=2101925837"