(Q43639978)

English

Low concentration N-methyl-N'-nitro-N-nitrosoguanidine activates DNA polymerase-beta expression via cyclic-AMP-protein kinase A-cAMP response element binding protein pathway

scientific article published in July 2001

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Europe PubMed Central

PubMed publication ID

25 November 2017

Low concentration N-methyl-N'-nitro-N-nitrosoguanidine activates DNA polymerase-beta expression via cyclic-AMP-protein kinase A-cAMP response element binding protein pathway (English)

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Europe PubMed Central

PubMed publication ID

25 November 2017

author name string

Wang G

1

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Europe PubMed Central

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25 November 2017

Yu Y

2

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Europe PubMed Central

PubMed publication ID

25 November 2017

Chen X

3

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25 November 2017

Xie H

4

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25 November 2017

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publication date

1 July 2001

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25 November 2017

Mutation Research

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25 November 2017

478

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25 November 2017

1-2

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Europe PubMed Central

PubMed publication ID

25 November 2017

177-184

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Europe PubMed Central

PubMed publication ID

25 November 2017

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The fidelity of DNA polymerase beta during distributive and processive DNA synthesis

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Mammalian beta-polymerase promoter: large-scale purification and properties of ATF/CREB palindrome binding protein from bovine testes.

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Nuclear protein phosphatase 2A dephosphorylates protein kinase A-phosphorylated CREB and regulates CREB transcriptional stimulation

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Nerve growth factor activates extracellular signal-regulated kinase and p38 mitogen-activated protein kinase pathways to stimulate CREB serine 133 phosphorylation

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DNA damage response of cloned DNA beta-polymerase promoter is blocked in mutant cell lines deficient in protein kinase A

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Evidence for a role for DNA polymerase beta in mammalian meiosis

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In vitro bypass replication of the cisplatin-d(GpG) lesion by calf thymus DNA polymerase beta and human immunodeficiency virus type I reverse transcriptase is highly mutagenic

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Overexpression of DNA polymerase beta in cell results in a mutator phenotype and a decreased sensitivity to anticancer drugs

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Induction of beta-polymerase mRNA by DNA-damaging agents in Chinese hamster ovary cells

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Phorbol ester abrogates up-regulation of DNA polymerase beta by DNA-alkylating agents in Chinese hamster ovary cells.

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Regulation of camp-inducible genes by creb

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Coupling of hormonal stimulation and transcription via the cyclic AMP-responsive factor CREB is rate limited by nuclear entry of protein kinase A.

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The cAMP-regulated transcription factor CREB interacts with a component of the TFIID complex

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Phosphorylation of CREB at Ser-133 induces complex formation with CREB-binding protein via a direct mechanism

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DNA damage-induced transcriptional activation of a human DNA polymerase beta chimeric promoter: recruitment of preinitiation complex in vitro by ATF/CREB.

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A dominant-negative mutant of human poly(ADP-ribose) polymerase affects cell recovery, apoptosis, and sister chromatid exchange following DNA damage

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Response of human keratinocytes to extremely low concentrations of N-methyl-N'-nitro-N-nitrosoguanidine

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Risk assessments of low-level exposures

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CREB is a regulatory target for the protein kinase Akt/PKB

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The transcriptional activity of NF-kappaB is regulated by the IkappaB-associated PKAc subunit through a cyclic AMP-independent mechanism

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Transforming growth factor-beta1 stimulates protein kinase A in mesangial cells

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Prostaglandin E2 stimulates cyclic AMP-mediated hyaluronan synthesis in rabbit pericardial mesothelial cells

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Isoprenaline induction of cAMP-phosphodiesterase in guinea-pig macrophages occurs in the presence, but not in the absence, of the phosphodiesterase type IV inhibitor rolipram

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Identifiers

10.1016/S0027-5107(01)00146-4

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

25 November 2017

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