(Q43675409)

English

Side chain hydroxylations in bile acid biosynthesis catalyzed by CYP3A are markedly up-regulated in Cyp27-/- mice but not in cerebrotendinous xanthomatosis.

scientific article published on 13 July 2001

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11454857%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

Side chain hydroxylations in bile acid biosynthesis catalyzed by CYP3A are markedly up-regulated in Cyp27-/- mice but not in cerebrotendinous xanthomatosis (English)

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11454857%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1

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9 November 2019

author name string

G Salen

2

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9 November 2019

Y Matsuzaki

3

1 reference

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9 November 2019

A K Batta

4

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9 November 2019

G Xu

5

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9 November 2019

E Leitersdorf

6

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9 November 2019

G S Tint

7

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9 November 2019

S K Erickson

8

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9 November 2019

N Tanaka

9

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9 November 2019

S Shefer

10

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9 November 2019

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publication date

13 July 2001

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9 November 2019

Journal of Biological Chemistry

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9 November 2019

276

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9 November 2019

37

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9 November 2019

34579-34585

1 reference

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9 November 2019

Biosynthesis of bile acids in cerebrotendinous xanthomatosis. Relationship of bile acid pool sizes and synthesis rates to hydroxylations at C-12, C-25, and C-26

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103025200

21 January 2018

A 25-hydroxylation pathway of cholic acid biosynthesis in man and rat

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103025200

21 January 2018

Cholic acid biosynthesis: the enzymatic defect in cerebrotendinous xanthomatosis

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103025200

21 January 2018

Frameshift and splice-junction mutations in the sterol 27-hydroxylase gene cause cerebrotendinous xanthomatosis in Jews or Moroccan origin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103025200

21 January 2018

Markedly reduced bile acid synthesis but maintained levels of cholesterol and vitamin D metabolites in mice with disrupted sterol 27-hydroxylase gene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103025200

21 January 2018

Identification of CYP3A4 as the major enzyme responsible for 25-hydroxylation of 5beta-cholestane-3alpha,7alpha,12alpha-triol in human liver microsomes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103025200

21 January 2018

24-, 25- and 27-hydroxylation of cholesterol by a purified preparation of 27-hydroxylase from pig liver

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103025200

21 January 2018

Unique property of liver mitochondrial P450 to catalyze the two physiologically important reactions involved in both cholesterol catabolism and vitamin D activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103025200

21 January 2018

Specificity of substrate and inhibitor probes for cytochrome P450s: evaluation of in vitro metabolism using cDNA-expressed human P450s and human liver microsomes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103025200

21 January 2018

Gene structure of mouse Cyp3a11: evidence for an enhancer element within its 5' flanking sequences.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103025200

21 January 2018

Cytochrome P450 CYP3A in human renal cell cancer.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103025200

21 January 2018

Disruption of the sterol 27-hydroxylase gene in mice results in hepatomegaly and hypertriglyceridemia. Reversal by cholic acid feeding.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103025200

21 January 2018

The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103025200

21 January 2018

Enzymatic characteristics of CO-sensitive 26-hydroxylase system for 5beta-cholestane-3 alpha, 7 alpha, 12 alpha-triol in rat-liver mitochondria and its intramitochondrial localization

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103025200

21 January 2018

Stero-bile acids and bile sterols. 47. Syntheses of 3alpha,7alpha,12alpha,25,26- and 3alpha,7alpha,12alpha,24,25-pentahydroxycoprostanes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103025200

21 January 2018

Simultaneous assay of the activities of two key enzymes in cholesterol metabolism by gas chromatography-mass spectrometry

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103025200

21 January 2018

Synthesis of potential C27-intermediates in bile acid biosynthesis and their deuterium-labeled analogs

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103025200

21 January 2018

On the mechanism of the enzymatic conversn of cholest-5-ene-3-beta, 7-alpha-diol into 7-alpha-hydroxycholest-4-en-3-one

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103025200

21 January 2018

An improved method for assay of cholesterol 7 alpha-hydroxylase activity

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103025200

21 January 2018

Assays for cholesterol 7 alpha-hydroxylase and 12 alpha-hydroxylase using high performance liquid chromatography

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103025200

21 January 2018

Isolation of a cytochrome P-450 that catalyzes the 25-hydroxylation of vitamin D3 from rat liver microsomes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103025200

21 January 2018

Mechanism-based inactivation of human liver microsomal cytochrome P-450 IIIA4 by gestodene

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M103025200

21 January 2018

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