(Q43705717)

26 November 2017

title

Inhibitors of phosphodiesterase isoforms III or IV suppress islet-cell nitric oxide production (English)

1 reference

26 November 2017

Beshay E

1

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26 November 2017

Prud'homme GJ

series ordinal

2

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26 November 2017

publication date

1 August 2001

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26 November 2017

published in

Laboratory Investigation

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26 November 2017

volume

81

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26 November 2017

issue

8

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26 November 2017

page(s)

1109-1117

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The phosphodiesterase inhibitors pentoxifylline and rolipram suppress macrophage activation and nitric oxide production in vitro and in vivo

26 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.3780323

Therapeutic potential of phosphodiesterase-4 and -3 inhibitors in Th1-mediated autoimmune diseases

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Nitric oxide production by murine macrophages is inhibited by prolonged elevation of cyclic AMP.

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Intraislet release of interleukin 1 inhibits beta cell function by inducing beta cell expression of inducible nitric oxide synthase

21 January 2018

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Nitric oxide mediates cytokine-induced inhibition of insulin secretion by human islets of Langerhans

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Nitric oxide synthase: expression and expressional control of the three isoforms.

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Interferon-gamma increases the sensitivity of islets of Langerhans for inducible nitric-oxide synthase expression induced by interleukin 1.

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Cytokines induce apoptosis in beta-cells isolated from mice lacking the inducible isoform of nitric oxide synthase (iNOS-/-).

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Modulation of inducible nitric oxide synthase in RINm5F cells

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The physiology and pathophysiology of the nitric oxide/superoxide system

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Stimulation of the nitric oxide synthase pathway in human hepatocytes by cytokines and endotoxin

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Increasing cAMP attenuates induction of inducible nitric-oxide synthase in rat primary astrocytes

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Prevention of autoimmune diabetes by intramuscular gene therapy with a nonviral vector encoding an interferon-gamma receptor/IgG1 fusion protein

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DNA fluorometric assay in 96-well tissue culture plates using Hoechst 33258 after cell lysis by freezing in distilled water

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PDE isoenzymes as targets for anti-asthma drugs

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Genetic and pathogenic basis of autoimmune diabetes in NOD mice

21 January 2018

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The antidepressant rolipram suppresses cytokine production and prevents autoimmune encephalomyelitis

21 January 2018

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Interleukin-1 beta-induced nitric oxide production from isolated rat islets is modulated by D-glucose and 3-isobutyl-1-methyl xanthine

21 January 2018

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7 January 2021

Glucagon decreases cytokine induction of nitric oxide synthase and action on insulin secretion in RIN5F cells and rat and human islets of Langerhans

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7 January 2021

Cytotoxic action of IL-1 beta against pancreatic islets is mediated via nitric oxide formation and is inhibited by NG-monomethyl-L-arginine

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Comparison of the effects of cilostazol and milrinone on intracellular cAMP levels and cellular function in platelets and cardiac cells

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7 January 2021

Reduced sensitivity of inducible nitric oxide synthase-deficient mice to multiple low-dose streptozotocin-induced diabetes

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7 January 2021

Effect of pentoxifylline on nitric oxide released by murine macrophages

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7 January 2021

Preferential infiltration of macrophages during early stages of insulitis in diabetes-prone BB rats

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7 January 2021

The phosphodiesterase inhibitors pentoxifylline and rolipram prevent diabetes in NOD mice

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7 January 2021

Cyclic AMP phosphodiesterases of human and rat islets of Langerhans: contributions of types III and IV to the modulation of insulin secretion

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7 January 2021

Cytokines and their roles in pancreatic islet beta-cell destruction and insulin-dependent diabetes mellitus

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7 January 2021

Phosphodiesterase inhibitor pentoxifylline, a selective suppressor of T helper type 1- but not type 2-associated lymphokine production, prevents induction of experimental autoimmune encephalomyelitis in Lewis rats

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.3780323

7 January 2021

Pentoxifylline suppresses irritant and contact hypersensitivity reactions

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https://api.crossref.org/works/10.1038%2FLABINVEST.3780323

7 January 2021

Inhibition of insulin secretion by interleukin-1 beta and tumour necrosis factor-alpha via an L-arginine-dependent nitric oxide generating mechanism

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https://api.crossref.org/works/10.1038%2FLABINVEST.3780323

7 January 2021

Effect of exogenous and endogenous nitric oxide on mitochondrial respiration of rat hepatocytes

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https://api.crossref.org/works/10.1038%2FLABINVEST.3780323

7 January 2021

Cell-specific effects of pentoxifylline on nitric oxide production and inducible nitric oxide synthase mRNA expression

1 reference

https://api.crossref.org/works/10.1038%2FLABINVEST.3780323

7 January 2021

10.1038/LABINVEST.3780323

Identifiers

DOI

1 reference

26 November 2017

1 reference