(Q43735137)

English

Identification of determinants of inverse agonism in a constitutively active parathyroid hormone/parathyroid hormone-related peptide receptor by photoaffinity cross-linking and mutational analysis

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

Identification of determinants of inverse agonism in a constitutively active parathyroid hormone/parathyroid hormone-related peptide receptor by photoaffinity cross-linking and mutational analysis (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

author name string

Gensure RC

1

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

Carter PH

2

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

Petroni BD

3

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

Jüppner H

4

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

Gardella TJ

5

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

language of work or name

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publication date

11 September 2001

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Europe PubMed Central

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26 November 2017

Journal of Biological Chemistry

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Europe PubMed Central

PubMed publication ID

26 November 2017

276

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Europe PubMed Central

PubMed publication ID

26 November 2017

46

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

42692-42699

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

Multiple sites of contact between the carboxyl-terminal binding domain of PTHrP-(1--36) analogs and the amino-terminal extracellular domain of the PTH/PTHrP receptor identified by photoaffinity cross-linking

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106215200

21 January 2018

Evaluating the signal transduction mechanism of the parathyroid hormone 1 receptor. Effect of receptor-G-protein interaction on the ligand binding mechanism and receptor conformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106215200

21 January 2018

Studies of the N-terminal region of a parathyroid hormone-related peptide (1-36) analog: receptor subtype-selective agonists, antagonists, and photochemical cross-linking agents

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106215200

21 January 2018

Removal of partial agonism from parathyroid hormone (PTH)-related protein-(7-34)NH2 by substitution of PTH amino acids at positions 10 and 11.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106215200

21 January 2018

Inverse agonism at G protein-coupled receptors: (patho)physiological relevance and implications for drug discovery

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106215200

21 January 2018

Inverse, protean, and ligand-selective agonism: matters of receptor conformation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106215200

21 January 2018

Constitutively active mutants of the beta1-adrenergic receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106215200

21 January 2018

Inverse agonism of histamine H2 antagonist accounts for upregulation of spontaneously active histamine H2 receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106215200

21 January 2018

Constitutive activity of the histamine H(1) receptor reveals inverse agonism of histamine H(1) receptor antagonists

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106215200

21 January 2018

Treatment with inverse agonists enhances baseline atrial contractility in transgenic mice with chronic beta2-adrenoceptor activation

1 reference

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21 January 2018

Evidence that antipsychotic drugs are inverse agonists at D2 dopamine receptors

1 reference

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21 January 2018

Antagonists with negative intrinsic activity at delta opioid receptors coupled to GTP-binding proteins

1 reference

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21 January 2018

A constitutively active mutant PTH-PTHrP receptor in Jansen-type metaphyseal chondrodysplasia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106215200

21 January 2018

Constitutively activated receptors for parathyroid hormone and parathyroid hormone-related peptide in Jansen's metaphyseal chondrodysplasia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106215200

21 January 2018

A novel parathyroid hormone (PTH)/PTH-related peptide receptor mutation in Jansen's metaphyseal chondrodysplasia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106215200

21 January 2018

Activated parathyroid hormone/parathyroid hormone-related protein receptor in osteoblastic cells differentially affects cortical and trabecular bone

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106215200

21 January 2018

Inverse agonism of amino-terminally truncated parathyroid hormone (PTH) and PTH-related peptide (PTHrP) analogs revealed with constitutively active mutant PTH/PTHrP receptors

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106215200

21 January 2018

Selective and nonselective inverse agonists for constitutively active type-1 parathyroid hormone receptors: evidence for altered receptor conformations

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106215200

21 January 2018

Rapid and efficient site-specific mutagenesis without phenotypic selection

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106215200

21 January 2018

Homolog-scanning mutagenesis of the parathyroid hormone (PTH) receptor reveals PTH-(1-34) binding determinants in the third extracellular loop

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106215200

21 January 2018

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106215200

21 January 2018

Tricine-sodium dodecyl sulfate-polyacrylamide gel electrophoresis for the separation of proteins in the range from 1 to 100 kDa

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106215200

21 January 2018

Nonlinear regression using spreadsheets.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106215200

21 January 2018

Identification of methionine as the site of covalent attachment of a p-benzoyl-phenylalanine-containing analogue of substance P on the substance P (NK-1) receptor.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106215200

21 January 2018

Parathyroid hormone-receptor interactions identified directly by photocross-linking and molecular modeling studies

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106215200

21 January 2018

Identification and functional expression of a receptor selectively recognizing parathyroid hormone, the PTH2 receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106215200

21 January 2018

Similar structures and shared switch mechanisms of the beta2-adrenoceptor and the parathyroid hormone receptor. Zn(II) bridges between helices III and VI block activation

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106215200

21 January 2018

Determinants of [Arg2]PTH-(1-34) binding and signaling in the transmembrane region of the parathyroid hormone receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106215200

21 January 2018

Differential conformational requirements for activation of G proteins and the regulatory proteins arrestin and G protein-coupled receptor kinase in the G protein-coupled receptor for parathyroid hormone (PTH)/PTH-related protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106215200

21 January 2018

Cellular distribution of constitutively active mutant parathyroid hormone (PTH)/PTH-related protein receptors and regulation of cyclic adenosine 3',5'-monophosphate signaling by beta-arrestin2.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106215200

21 January 2018

Transmembrane residues of the parathyroid hormone (PTH)/PTH-related peptide receptor that specifically affect binding and signaling by agonist ligands

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106215200

21 January 2018

A parathyroid hormone inhibitor in vivo: design and biological evaluation of a hormone analog

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106215200

21 January 2018

Full activation of chimeric receptors by hybrids between parathyroid hormone and calcitonin. Evidence for a common pattern of ligand-receptor interaction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106215200

21 January 2018

Photoaffinity cross-linking identifies differences in the interactions of an agonist and an antagonist with the parathyroid hormone/parathyroid hormone-related protein receptor

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106215200

21 January 2018

Residues in the membrane-spanning and extracellular loop regions of the parathyroid hormone (PTH)-2 receptor determine signaling selectivity for PTH and PTH-related peptide

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106215200

21 January 2018

Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106215200

21 January 2018

Characterization of the molecular motions of constitutively active G protein-coupled receptors for parathyroid hormone

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M106215200

21 January 2018

Identifiers

10.1074/JBC.M106215200

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

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