(Q43741286)

26 November 2017

title

FXa-induced responses in vascular wall cells are PAR-mediated and inhibited by ZK-807834. (English)

1 reference

26 November 2017

McLean K

1

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26 November 2017

Schirm S

2

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26 November 2017

Johns A

3

1 reference

26 November 2017

Morser J

4

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26 November 2017

Light DR

5

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26 November 2017

publication date

1 August 2001

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26 November 2017

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26 November 2017

volume

103

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26 November 2017

issue

4

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26 November 2017

page(s)

281-297

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Activation of Mac-1 (CD11b/CD18)-bound factor X by released cathepsin G defines an alternative pathway of leucocyte initiation of coagulation

26 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Sustained inhibition of whole-blood clot procoagulant activity by inhibition of thrombus-associated factor Xa

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Tissue Factor Mediates Prolonged Procoagulant Activity on the Luminal Surface of Balloon-Injured Aortas in Rabbits

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Prolonged activation of prothrombin on the vascular wall after arterial injury

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Thrombin potently stimulates cytokine production in human vascular smooth muscle cells but not in mononuclear phagocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Atypical protease-activated receptor mediates endothelium-dependent relaxation of human coronary arteries

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

The role of secondary growth factor production in thrombin-induced proliferation of vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Synchronized Ca2+ oscillations induced in Madin Darby canine kidney cells by bradykinin and thrombin but not by ATP

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

The human proteinase-activated receptor-3 (PAR-3) gene. Identification within a Par gene cluster and characterization in vascular endothelial cells and platelets

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Protease-activated receptors and their role in IL-6 and NF-IL-6 expression in human gingival fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Thrombin receptor expression and responsiveness of human monocytic cells to thrombin is linked to interferon-induced cellular differentiation

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Calcium mobilization and protease-activated receptor cleavage after thrombin stimulation in motor neurons

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Protease-activated receptor 3 is a second thrombin receptor in humans

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Cloning and characterization of human protease-activated receptor 4

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Evidence for proteinase-activated receptor-2 (PAR-2)-mediated mitogenesis in coronary artery smooth muscle cells

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Thrombin responses in human endothelial cells. Contributions from receptors other than PAR1 include the transactivation of PAR2 by thrombin-cleaved PAR1.

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

PAR3 is a cofactor for PAR4 activation by thrombin

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Hypotension and inflammatory cytokine gene expression triggered by factor Xa-nitric oxide signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Effector protease receptor 1 mediates the mitogenic activity of factor Xa for vascular smooth muscle cells in vitro and in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Protease-dependent T cell activation: ligation of effector cell protease receptor-1 (EPR-1) stimulates lymphocyte proliferation

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Vascular endothelial growth factor production by fibroblasts in response to factor VIIa binding to tissue factor involves thrombin and factor Xa.

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Activation-dependent exposure of the inter-EGF sequence Leu83-Leu88 in factor Xa mediates ligand binding to effector cell protease receptor-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Factor Xa activates endothelial cells by a receptor cascade between EPR-1 and PAR-2

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Discovery of N-[2-[5-[Amino(imino)methyl]-2-hydroxyphenoxy]-3, 5-difluoro-6-[3-(4, 5-dihydro-1-methyl-1H-imidazol-2-yl)phenoxy]pyridin-4-yl]-N-methylgl y cine (ZK-807834): a potent, selective, and orally active inhibitor of the blood coagulation enz

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Contribution of the prothrombin fragment 2 domain to the function of factor Va in the prothrombinase complex

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Mechanisms of initiation and termination of signalling by neuropeptide receptors: a comparison with the proteinase-activated receptors

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Ligand cross-reactivity within the protease-activated receptor family.

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Effector cell protease receptor-1, a platelet activation-dependent membrane protein, regulates prothrombinase-catalyzed thrombin generation

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Molecular dissection of effector cell protease receptor-1 recognition of factor Xa. Assignment of critical residues involved in antibody reactivity and ligand binding

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Activation of human vascular endothelial cells by factor Xa: effect of specific inhibitors

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Role of proexosite I in factor Va-dependent substrate interactions of prothrombin activation

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Characterization of proexosite I on prothrombin

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Induction of vascular smooth muscle cell growth by selective activation of the proteinase activated receptor-2 (PAR-2)

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Characterization of the inflammatory response to proteinase-activated receptor-2 (PAR2)-activating peptides in the rat paw.

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Factor Xa as an interface between coagulation and inflammation. Molecular mimicry of factor Xa association with effector cell protease receptor-1 induces acute inflammation in vivo

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Thrombin functions as an inflammatory mediator through activation of its receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Increasing Levels of Interleukin (IL)-1Ra and IL-6 During the First 2 Days of Hospitalization in Unstable Angina Are Associated With Increased Risk of In-Hospital Coronary Events

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Elevated Levels of Interleukin-6 in Unstable Angina

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Inflammatory profile in unstable angina versus stable angina in patients undergoing percutaneous interventions

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Tissue factor pathway inhibitor reduces mortality from Escherichia coli septic shock

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Specific factor Xa inhibition reduces restenosis after balloon angioplasty of atherosclerotic femoral arteries in rabbits

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Effects of a factor Xa inhibitor, DX-9065a, in a novel rabbit model of venous thrombosis

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Coronary-artery stenting compared with balloon angioplasty for restenosis after initial balloon angioplasty. Restenosis Stent Study Group

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Influence of Blockade at Specific Levels of the Coagulation Cascade on Restenosis in a Rabbit Atherosclerotic Femoral Artery Injury Model

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

Effects of ZK-807834, a novel inhibitor of factor Xa, on arterial and venous thrombosis in rabbits

1 reference

https://api.crossref.org/works/10.1016%2FS0049-3848%2801%2900330-9

7 January 2021

10.1016/S0049-3848(01)00330-9

Identifiers

DOI

1 reference

26 November 2017

1 reference