(Q43747154)

English

Adenovirus-mediated expression of HSV1-TK or Fas ligand induces cell death in primary human glioma-derived cell cultures that are resistant to the chemotherapeutic agent CCNU.

scientific article published in August 2001

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

Adenovirus-mediated expression of HSV1-TK or Fas ligand induces cell death in primary human glioma-derived cell cultures that are resistant to the chemotherapeutic agent CCNU. (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

1 reference

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inferred from title

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Maria G. Castro

4

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

author name string

Maleniak TC

1

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

Darling JL

2

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

Lowenstein PR

3

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

publication date

1 August 2001

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

Cancer Gene Therapy

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

8

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

589-598

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

https://scigraph.springernature.com/pub.10.1038/sj.cgt.7700348

0 references

The new WHO classification of brain tumours

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700348

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Glioblastoma multiforme: the terminator

1 reference

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Treatment of advanced CNS malignancies with the recombinant adenovirus H5.010RSVTK: a phase I trial.

1 reference

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7 January 2021

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Heterogeneity of chemosensitivity in six clonal cell lines derived from a spontaneous murine astrocytoma and its relationship to genotypic and phenotypic characteristics

1 reference

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7 January 2021

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Gene therapy of glioblastoma multiforme via combined expression of suicide and cytokine genes: a pilot study in humans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700348

7 January 2021

based on heuristic

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A phase 1-2 clinical trial of gene therapy for recurrent glioblastoma multiforme by tumor transduction with the herpes simplex thymidine kinase gene followed by ganciclovir. GLI328 European-Canadian Study Group

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700348

7 January 2021

based on heuristic

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Phase I study of adenoviral delivery of the HSV-tk gene and ganciclovir administration in patients with current malignant brain tumors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700348

7 January 2021

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Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trial

1 reference

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7 January 2021

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Toxicity evaluation of replication-competent herpes simplex virus (ICP 34.5 null mutant 1716) in patients with recurrent malignant glioma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700348

7 January 2021

based on heuristic

inferred from DOI database lookup

Thymidine kinase gene therapy for human malignant glioma, using replication-deficient retroviruses or adenoviruses

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700348

7 January 2021

based on heuristic

inferred from DOI database lookup

Gene therapy for brain tumors: regression of experimental gliomas by adenovirus-mediated gene transfer in vivo

1 reference

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7 January 2021

based on heuristic

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Chronic brain inflammation and persistent herpes simplex virus 1 thymidine kinase expression in survivors of syngeneic glioma treated by adenovirus-mediated gene therapy: implications for clinical trials

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700348

7 January 2021

based on heuristic

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Variable efficiency of the thymidine kinase/ganciclovir system in human glioblastoma cell lines: implications for gene therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700348

7 January 2021

based on heuristic

inferred from DOI database lookup

Apoptosis by retrovirus- and adenovirus-mediated gene transfer of Fas ligand to glioma cells: implications for gene therapy.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700348

7 January 2021

based on heuristic

inferred from DOI database lookup

Treatment of experimental glioma by administration of adenoviral vectors expressing Fas ligand

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700348

7 January 2021

based on heuristic

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Adenovirus-mediated transfer of p53 and Fas ligand drastically enhances apoptosis in gliomas

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700348

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell type-specific expression in brain cell cultures from a short human cytomegalovirus major immediate early promoter depends on whether it is inserted into herpesvirus or adenovirus vectors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700348

7 January 2021

based on heuristic

inferred from DOI database lookup

Central nervous system toxicity of two adenoviral vectors encoding variants of the herpes simplex virus type 1 thymidine kinase: reduced cytotoxicity of a truncated HSV1-TK.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700348

7 January 2021

based on heuristic

inferred from DOI database lookup

FasL induces Fas/Apo1-mediated apoptosis in human embryonic kidney 293 cells routinely used to generate E1-deleted adenoviral vectors.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700348

7 January 2021

based on heuristic

inferred from DOI database lookup

Neuronal and glial cell type-specific promoters within adenovirus recombinants restrict the expression of the apoptosis-inducing molecule Fas ligand to predetermined brain cell types, and abolish peripheral liver toxicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700348

7 January 2021

based on heuristic

inferred from DOI database lookup

Gene Transfer into Neural Cells In Vitro Using Adenoviral Vectors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700348

7 January 2021

based on heuristic

inferred from DOI database lookup

Supernatant rescue assay vs. polymerase chain reaction for detection of wild type adenovirus-contaminating recombinant adenovirus stocks

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700348

7 January 2021

based on heuristic

inferred from DOI database lookup

Adenoviral vector which delivers FasL-GFP fusion protein regulated by the tet-inducible expression system

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700348

7 January 2021

based on heuristic

inferred from DOI database lookup

Transcriptional targeting to anterior pituitary lactotrophic cells using recombinant adenovirus vectors in vitro and in vivo in normal and estrogen/sulpiride-induced hyperplastic anterior pituitaries

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700348

7 January 2021

based on heuristic

inferred from DOI database lookup

Use of Escherichiu coli (E. coli) lacZ (β-Galactosidase) as a Reporter Gene.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700348

7 January 2021

based on heuristic

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Chapter 4 Quantification of Apoptotic Events in Pure and Heterogeneous Populations of Cells Using the Flow Cytometer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700348

7 January 2021

based on heuristic

inferred from DOI database lookup

A truncated herpes simplex virus thymidine kinase phosphorylates thymidine and nucleoside analogs and does not cause sterility in transgenic mice.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700348

7 January 2021

based on heuristic

inferred from DOI database lookup

Apoptosis by death factor

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700348

7 January 2021

based on heuristic

inferred from DOI database lookup

The Fas counterattack: Fas-mediated T cell killing by colon cancer cells expressing Fas ligand

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700348

7 January 2021

based on heuristic

inferred from DOI database lookup

Melanoma cell expression of Fas(Apo-1/CD95) ligand: implications for tumor immune escape

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700348

7 January 2021

based on heuristic

inferred from DOI database lookup

Strong promoters are the key to highly efficient, noninflammatory and noncytotoxic adenoviral-mediated transgene delivery into the brain in vivo

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700348

7 January 2021

based on heuristic

inferred from DOI database lookup

Cell-type-specific and regulatable transgenesis in the adult brain: adenovirus-encoded combined transcriptional targeting and inducible transgene expression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700348

7 January 2021

based on heuristic

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Peripheral infection with adenovirus causes unexpected long-term brain inflammation in animals injected intracranially with first-generation, but not with high-capacity, adenovirus vectors: toward realistic long-term neurological gene therapy for ch

1 reference

https://api.crossref.org/works/10.1038%2FSJ.CGT.7700348

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based on heuristic

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a controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer

1 reference

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based on heuristic

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Identifiers

10.1038/SJ.CGT.7700348

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

Dimensions Publication ID

0 references

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

ResearchGate publication ID

0 references

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