(Q43760463)

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Activation of procollagenases is a key control point in cartilage collagen degradation: interaction of serine and metalloproteinase pathways

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scholarly article

1 reference

Europe PubMed Central

26 November 2017

Activation of procollagenases is a key control point in cartilage collagen degradation: interaction of serine and metalloproteinase pathways (English)

1 reference

Europe PubMed Central

26 November 2017

1 reference

based on heuristic

inferred from title

author name string

Milner JM

1

1 reference

Europe PubMed Central

26 November 2017

Elliott SF

2

1 reference

Europe PubMed Central

26 November 2017

Cawston TE

3

1 reference

Europe PubMed Central

26 November 2017

publication date

1 September 2001

1 reference

Europe PubMed Central

26 November 2017

Arthritis & Rheumatology

1 reference

Europe PubMed Central

26 November 2017

44

1 reference

Europe PubMed Central

26 November 2017

2084-2096

1 reference

Europe PubMed Central

26 November 2017

9

1 reference

Europe PubMed Central

26 November 2017

The chondrocyte, architect of cartilage. Biomechanics, structure, function and molecular biology of cartilage matrix macromolecules

1 reference

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21 January 2018

In vivo studies of articular tissue damage mediated by catabolin/interleukin 1.

1 reference

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21 January 2018

Pig catabolin is a form of interleukin 1. Cartilage and bone resorb, fibroblasts make prostaglandin and collagenase, and thymocyte proliferation is augmented in response to one protein.

1 reference

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21 January 2018

In vivo studies of cartilage regeneration after damage induced by catabolin/interleukin-1.

1 reference

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21 January 2018

Matrix metalloproteinases: a review

1 reference

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21 January 2018

The matrix-degrading metalloproteinases

1 reference

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21 January 2018

Human skin collagenase: isolation of precursor and active forms from both fibroblast and organ cultures

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21 January 2018

Matrix metalloproteinase-2 is an interstitial collagenase. Inhibitor-free enzyme catalyzes the cleavage of collagen fibrils and soluble native type I collagen generating the specific 3/4- and 1/4-length fragments.

1 reference

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21 January 2018

Membrane type 1 matrix metalloproteinase digests interstitial collagens and other extracellular matrix macromolecules

1 reference

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21 January 2018

Damage to type II collagen in aging and osteoarthritis starts at the articular surface, originates around chondrocytes, and extends into the cartilage with progressive degeneration

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21 January 2018

Analysis of 16 different matrix metalloproteinases (MMP-1 to MMP-20) in the synovial membrane: different profiles in trauma and rheumatoid arthritis

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21 January 2018

Characterization of collagenase 3 (matrix metalloproteinase 13) messenger RNA expression in the synovial membrane and synovial fibroblasts of patients with rheumatoid arthritis

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21 January 2018

Collagenase: a key enzyme in collagen turnover

1 reference

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21 January 2018

Enhanced cleavage of type II collagen by collagenases in osteoarthritic articular cartilage

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21 January 2018

Tissue inhibitors of metalloproteinases: evolution, structure and function

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21 January 2018

Stromelysin is an activator of procollagenase. A study with natural and recombinant enzymes

1 reference

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21 January 2018

Direct activation of human neutrophil procollagenase by recombinant stromelysin

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21 January 2018

Biochemical characterization of human collagenase-3

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21 January 2018

A matrix metalloproteinase expressed on the surface of invasive tumour cells

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21 January 2018

Identification of the second membrane-type matrix metalloproteinase (MT-MMP-2) gene from a human placenta cDNA library. MT-MMPs form a unique membrane-type subclass in the MMP family

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21 January 2018

Identification of soluble type of membrane-type matrix metalloproteinase-3 formed by alternatively spliced mRNA

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21 January 2018

Identification and characterization of the fifth membrane-type matrix metalloproteinase MT5-MMP.

1 reference

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21 January 2018

Furin-dependent intracellular activation of the human stromelysin-3 zymogen

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21 January 2018

Tissue cooperation in a proteolytic cascade activating human interstitial collagenase

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21 January 2018

Further studies on the activation of procollagenase, the latent precursor of bone collagenase. Effects of lysosomal cathepsin B, plasmin and kallikrein, and spontaneous activation

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21 January 2018

Endogenous activation of latent collagenase by rheumatoid synovial cells. Evidence for a role of plasminogen activator

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21 January 2018

The urokinase-type plasminogen activator system in cancer metastasis: a review

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21 January 2018

Analysis of intraarticular fibrinolytic pathways in patients with inflammatory and noninflammatory joint diseases

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21 January 2018

Plasminogen activators and their inhibitors in synovial fluids from normal, osteoarthritis, and rheumatoid arthritis knees

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21 January 2018

Mechanism-based isocoumarin inhibitors for serine proteases: use of active site structure and substrate specificity in inhibitor design

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21 January 2018

A serine proteinase inactivator inhibits chondrocyte-mediated cartilage proteoglycan breakdown occurring in response to proinflammatory cytokines

1 reference

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21 January 2018

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21 January 2018

A rapid and reproducible assay for collagenase using [1-14C]acetylated collagen

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21 January 2018

Differential effects of bFGF and IGF-I on matrix metabolism in calf and adult bovine cartilage explants

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21 January 2018

Insulin-like growth factors maintain steady-state metabolism of proteoglycans in bovine articular cartilage explants

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21 January 2018

Insulin-like growth factor 1 can decrease degradation and promote synthesis of proteoglycan in cartilage exposed to cytokines

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21 January 2018

Human urinary trypsin inhibitor inhibits the activation of pro-matrix metalloproteinases and proteoglycans release in rabbit articular cartilage.

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21 January 2018

Activation of matrix metalloproteinase-9 (MMP-9) via a converging plasmin/stromelysin-1 cascade enhances tumor cell invasion

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21 January 2018

Lysosomal cysteine endopeptidases mediate interleukin 1-stimulated cartilage proteoglycan degradation

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21 January 2018

Induction of matrix metalloproteinase activation cascades based on membrane-type 1 matrix metalloproteinase: associated activation of gelatinase A, gelatinase B and collagenase 3.

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21 January 2018

Cellular mechanisms for human procollagenase-3 (MMP-13) activation. Evidence that MT1-MMP (MMP-14) and gelatinase a (MMP-2) are able to generate active enzyme

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21 January 2018

Matrix metalloproteinase 13 (collagenase 3) in human rheumatoid synovium

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21 January 2018

The breakdown of collagen by chondrocytes

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21 January 2018

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21 January 2018

Degradation of type II collagen, but not proteoglycan, correlates with matrix metalloproteinase activity in cartilage explant cultures

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21 January 2018

Differential in vivo expression of collagenase messenger RNA in synovium and cartilage. Quantitative comparison with stromelysin messenger RNA levels in human rheumatoid arthritis and osteoarthritis patients and in two animal models of acute inflamm

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21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

Interleukin-1 and oncostatin M in combination promote the release of collagen fragments from bovine nasal cartilage in culture

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21 January 2018

Cartilage synthesizes the serine protease inhibitor PAI-1: support for the involvement of serine proteases in cartilage remodeling

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21 January 2018

Recombinant human interleukin-1 stimulates human articular cartilage to undergo resorption and human chondrocytes to produce both tissue- and urokinase-type plasminogen activator

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21 January 2018

Recombinant human inteleukin-1 inhibits plasminogen activator inhibitor-1 (PAI-1) production by human articular cartilage and chondrocytes

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21 January 2018

Preparation of recombinant tissue inhibitor of metalloproteinases-1 (TIMP-1) in high yield and identification of a hydrophobic surface feature

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21 January 2018

96-Well plate assays for measuring collagenase activity using (3)H-acetylated collagen

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21 January 2018

The effect of serum on biosynthesis of proteoglycans by bovine articular cartilage in culture

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21 January 2018

Collagen degradation induced by the combination of IL-1alpha and plasminogen in rabbit articular cartilage explant culture

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21 January 2018

The regulation of MMPs and TIMPs in cartilage turnover

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21 January 2018

Mechanism-based isocoumarin inhibitors for trypsin and blood coagulation serine proteases: new anticoagulants

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21 January 2018

The role of plasminogen in cell-mediated collagen degradation

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21 January 2018

Plasminogen modulation of IL-1-stimulated degradation in bovine and human articular cartilage explants. The role of the endogenous inhibitors: PAI-1, alpha 2-antiplasmin, alpha 1-PI, alpha 2-macroglobulin and TIMP

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21 January 2018

Regulation of ProMMP-1 and ProMMP-3 activation by tissue factor pathway inhibitor-2/matrix-associated serine protease inhibitor

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21 January 2018

Cartilage degradation and invasion by rheumatoid synovial fibroblasts is inhibited by gene transfer of a cell surface-targeted plasmin inhibitor

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21 January 2018

Induction of alpha1-antitrypsin synthesis in human articular chondrocytes by interleukin-6-type cytokines: evidence for a local acute-phase response in the joint

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21 January 2018

Oncostatin M stimulates urokinase-type plasminogen activator activity in human synovial fibroblasts

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21 January 2018

A novel host/tumor cell interaction activates matrix metalloproteinase 1 and mediates invasion through type I collagen

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21 January 2018

Cleavage of aggrecan at the Asn341-Phe342 site coincides with the initiation of collagen damage in murine antigen-induced arthritis: a pivotal role for stromelysin 1 in matrix metalloproteinase activity

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21 January 2018

Inhibition of cartilage proteoglycan release by a specific inactivator of cathepsin B and an inhibitor of matrix metalloproteinases. Evidence for two converging pathways of chondrocyte-mediated proteoglycan degradation

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21 January 2018

Cytokine-induced endogenous procollagenase stored in the extracellular matrix of soft connective tissue results in a burst of collagen breakdown following its activation

1 reference

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21 January 2018

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10.1002/1529-0131(200109)44:9<2084::AID-ART359>3.0.CO;2-R

1 reference

Europe PubMed Central

26 November 2017

release_ue3o5ccb6vcxhoqlgigvsmiax4

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https://api.fatcat.wiki/v0/release/ue3o5ccb6vcxhoqlgigvsmiax4

24 November 2022

based on heuristic

mapped directly with Wikidata item

1 reference

Europe PubMed Central

26 November 2017

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