(Q43760476)

English

The molecular mechanism of action of the antiresorptive and antiinflammatory drug clodronate: evidence for the formation in vivo of a metabolite that inhibits bone resorption and causes osteoclast and macrophage apoptosis

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scholarly article

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Europe PubMed Central

PubMed publication ID

26 November 2017

The molecular mechanism of action of the antiresorptive and antiinflammatory drug clodronate: evidence for the formation in vivo of a metabolite that inhibits bone resorption and causes osteoclast and macrophage apoptosis (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

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apoptotic process

1 reference

based on heuristic

inferred from title

author name string

Frith JC

1

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

Mönkkönen J

2

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

Auriola S

3

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

Mönkkönen H

4

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

Rogers MJ

5

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

publication date

1 September 2001

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

Arthritis & Rheumatology

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

44

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

9

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

2201-2210

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

Management of corticosteroid-induced osteoporosis

1 reference

https://api.crossref.org/works/10.1002%2F1529-0131%28200109%2944%3A9%3C2201%3A%3AAID-ART374%3E3.0.CO%3B2-E

21 January 2018

Diagnosis and management of osteoporosis in postmenopausal women: clinical guidelines. International Committee for Osteoporosis Clinical Guidelines.

1 reference

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21 January 2018

Goals of treatment for Paget's disease of bone

1 reference

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21 January 2018

Bisphosphonate action. Alendronate localization in rat bone and effects on osteoclast ultrastructure

1 reference

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21 January 2018

Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications

1 reference

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21 January 2018

Role of CD47 as a marker of self on red blood cells

1 reference

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21 January 2018

Clodronate (dichloromethylene bisphosphonate) inhibits LPS-stimulated IL-6 and TNF production by RAW 264 cells

1 reference

https://api.crossref.org/works/10.1002%2F1529-0131%28200109%2944%3A9%3C2201%3A%3AAID-ART374%3E3.0.CO%3B2-E

21 January 2018

Alendronate is a specific, nanomolar inhibitor of farnesyl diphosphate synthase

1 reference

https://api.crossref.org/works/10.1002%2F1529-0131%28200109%2944%3A9%3C2201%3A%3AAID-ART374%3E3.0.CO%3B2-E

21 January 2018

Alendronate mechanism of action: geranylgeraniol, an intermediate in the mevalonate pathway, prevents inhibition of osteoclast formation, bone resorption, and kinase activation in vitro

1 reference

https://api.crossref.org/works/10.1002%2F1529-0131%28200109%2944%3A9%3C2201%3A%3AAID-ART374%3E3.0.CO%3B2-E

21 January 2018

Protein geranylgeranylation is required for osteoclast formation, function, and survival: inhibition by bisphosphonates and GGTI-298.

1 reference

https://api.crossref.org/works/10.1002%2F1529-0131%28200109%2944%3A9%3C2201%3A%3AAID-ART374%3E3.0.CO%3B2-E

21 January 2018

Etidronate (EHDP) inhibits osteoclastic-bone resorption, promotes apoptosis and disrupts actin rings in isolate-mature osteoclasts.

1 reference

https://api.crossref.org/works/10.1002%2F1529-0131%28200109%2944%3A9%3C2201%3A%3AAID-ART374%3E3.0.CO%3B2-E

21 January 2018

Clodronate and liposome-encapsulated clodronate are metabolized to a toxic ATP analog, adenosine 5'-(beta, gamma-dichloromethylene) triphosphate, by mammalian cells in vitro.

1 reference

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21 January 2018

Growth inhibition of macrophage-like and other cell types by liposome-encapsulated, calcium-bound, and free bisphosphonates in vitro

1 reference

https://api.crossref.org/works/10.1002%2F1529-0131%28200109%2944%3A9%3C2201%3A%3AAID-ART374%3E3.0.CO%3B2-E

21 January 2018

Clodronate. A review of its pharmacological properties and therapeutic efficacy in resorptive bone disease

1 reference

https://api.crossref.org/works/10.1002%2F1529-0131%28200109%2944%3A9%3C2201%3A%3AAID-ART374%3E3.0.CO%3B2-E

21 January 2018

The role of geranylgeranylation in bone resorption and its suppression by bisphosphonates in fetal bone explants in vitro: A clue to the mechanism of action of nitrogen-containing bisphosphonates

1 reference

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21 January 2018

Inhibition of bone resorption by bisphosphonates: Interactions between bisphosphonates, osteoclasts, and bone

1 reference

https://api.crossref.org/works/10.1002%2F1529-0131%28200109%2944%3A9%3C2201%3A%3AAID-ART374%3E3.0.CO%3B2-E

21 January 2018

A possible mechanism of the specific action of bisphosphonates on osteoclasts: tiludronate preferentially affects polarized osteoclasts having ruffled borders

1 reference

https://api.crossref.org/works/10.1002%2F1529-0131%28200109%2944%3A9%3C2201%3A%3AAID-ART374%3E3.0.CO%3B2-E

21 January 2018

Suppression of experimental allergic encephalomyelitis in Lewis rats after elimination of macrophages

1 reference

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21 January 2018

Identifiers

10.1002/1529-0131(200109)44:9<2201::AID-ART374>3.0.CO;2-E

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 November 2017

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