(Q43766168)

26 November 2017

title

Systematic knockdown of morphine pathway enzymes in opium poppy using virus-induced gene silencing (English)

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26 November 2017

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26 November 2017

Champa P Wijekoon

1

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26 November 2017

publication date

28 December 2011

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26 November 2017

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26 November 2017

volume

69

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26 November 2017

issue

6

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26 November 2017

page(s)

1052-1063

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RNAi-mediated replacement of morphine with the nonnarcotic alkaloid reticuline in opium poppy

26 November 2017

cites work

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Enhancement of alkaloid production in opium and California poppy by transactivation using heterologous regulatory factors

21 January 2018

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Fast forward genetics based on virus-induced gene silencing

21 January 2018

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A tale of three cell types: alkaloid biosynthesis is localized to sieve elements in opium poppy

21 January 2018

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

21 January 2018

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Interactions among enzymes of the Arabidopsis flavonoid biosynthetic pathway

21 January 2018

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Förster resonance energy transfer demonstrates a flavonoid metabolon in living plant cells that displays competitive interactions between enzymes

21 January 2018

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Integration of deep transcriptome and proteome analyses reveals the components of alkaloid metabolism in opium poppy cell cultures

21 January 2018

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Virus-induced gene silencing as a tool for comparative functional studies in Thalictrum

21 January 2018

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Genetic transformation via somatic embryogenesis to establish herbicide-resistant opium poppy

21 January 2018

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Transformation of opium poppy (Papaver somniferum L.) with antisense berberine bridge enzyme gene (anti-bbe) via somatic embryogenesis results in an altered ratio of alkaloids in latex but not in roots

21 January 2018

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Metabolic engineering with a morphine biosynthetic P450 in opium poppy surpasses breeding

21 January 2018

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CYP719B1 is salutaridine synthase, the C-C phenol-coupling enzyme of morphine biosynthesis in opium poppy

21 January 2018

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Molecular characterization of the salutaridinol 7-O-acetyltransferase involved in morphine biosynthesis in opium poppy Papaver somniferum

21 January 2018

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Dioxygenases catalyze the O-demethylation steps of morphine biosynthesis in opium poppy.

21 January 2018

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Virus-induced gene silencing is an effective tool for assaying gene function in the basal eudicot species Papaver somniferum (opium poppy).

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-313X.2011.04855.X

1,2-Dehydroreticuline synthase, the branch point enzyme opening the morphinan biosynthetic pathway

21 January 2018

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RNAi suppression of the morphine biosynthetic gene salAT and evidence of association of pathway enzymes

21 January 2018

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Molecular cloning and heterologous expression of a cDNA encoding berbamunine synthase, a C--O phenol-coupling cytochrome P450 from the higher plant Berberis stolonifera

21 January 2018

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Metabolic engineering of dhurrin in transgenic Arabidopsis plants with marginal inadvertent effects on the metabolome and transcriptome

21 January 2018

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Morphology and Alkaloid Chemistry of Papaver setigerum DC. (Papaveraceae)

21 January 2018

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Norcoclaurine synthase is a member of the pathogenesis-related 10/Bet v1 protein family

21 January 2018

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Acetyl coenzyme A:salutaridinol-7-O-acetyltransferase from papaver somniferum plant cell cultures. The enzyme catalyzing the formation of thebaine in morphine biosynthesis

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-313X.2011.04855.X

Molecular cloning and characterization of tetrahydroprotoberberine cis-N-methyltransferase, an enzyme involved in alkaloid biosynthesis in opium poppy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-313X.2011.04855.X

Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-313X.2011.04855.X

Analgesia: morphine-pathway block in top1 poppies.

21 January 2018

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(R,S)-Reticuline 7-O-methyltransferase and (R,S)-norcoclaurine 6-O-methyltransferase of Papaver somniferum - cDNA cloning and characterization of methyl transfer enzymes of alkaloid biosynthesis in opium poppy

21 January 2018

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A polyamine metabolon involving aminopropyl transferase complexes in Arabidopsis.

21 January 2018

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Modulation of berberine bridge enzyme levels in transgenic root cultures of California poppy alters the accumulation of benzophenanthridine alkaloids

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-313X.2011.04855.X

Functional characterization of a novel benzylisoquinoline O-methyltransferase suggests its involvement in papaverine biosynthesis in opium poppy (Papaver somniferum L).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-313X.2011.04855.X

Electrospray tandem mass spectrometric investigations of morphinans

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1365-313X.2011.04855.X

VIGS vectors for gene silencing: many targets, many tools

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-313X.2011.04855.X

Methods for effective real-time RT-PCR analysis of virus-induced gene silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-313X.2011.04855.X

Molecular cloning and characterization of norcoclaurine synthase, an enzyme catalyzing the first committed step in benzylisoquinoline alkaloid biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-313X.2011.04855.X

The role of phloem sieve elements and laticifers in the biosynthesis and accumulation of alkaloids in opium poppy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-313X.2011.04855.X

Analysis of benzylisoquinoline-type alkaloids by electrospray tandem mass spectrometry and atmospheric pressure photoionization

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-313X.2011.04855.X

Partial purification and characterization of dihydrobenzophenanthridine oxidase from Eschscholtzia californica cell suspension cultures

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-313X.2011.04855.X

Molecular cloning and functional expression of codeinone reductase: the penultimate enzyme in morphine biosynthesis in the opium poppy Papaver somniferum

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-313X.2011.04855.X

Highly efficient virus-induced gene silencing (VIGS) in California poppy (Eschscholzia californica): an evaluation of VIGS as a strategy to obtain functional data from non-model plants

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-313X.2011.04855.X

The roles of latex and the vascular bundle in morphine biosynthesis in the opium poppy, Papaver somniferum

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-313X.2011.04855.X

Alkaloid biosynthesis: metabolism and trafficking.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-313X.2011.04855.X

Comparative macroarray analysis of morphine containing Papaver somniferum and eight morphine free Papaver species identifies an O-methyltransferase involved in benzylisoquinoline biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-313X.2011.04855.X

Gene transcript and metabolite profiling of elicitor-induced opium poppy cell cultures reveals the coordinate regulation of primary and secondary metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1365-313X.2011.04855.X

10.1111/J.1365-313X.2011.04855.X

21 January 2018

Identifiers

DOI

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26 November 2017

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