(Q43809940)

27 November 2017

title

Preclinical safety testing of DISC-hGMCSF to support phase I clinical trials in cancer patients (English)

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27 November 2017

main subject

phase I clinical trial

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author name string

Loudon PT

1

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Blakeley DM

2

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Boursnell ME

3

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Day DA

4

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Duncan IA

5

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Lowden RC

6

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McLean CS

7

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Martin G

8

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Miller JC

9

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Shaw ML

10

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publication date

1 September 2001

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27 November 2017

published in

Journal of Gene Medicine

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27 November 2017

volume

3

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27 November 2017

issue

5

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27 November 2017

page(s)

458-467

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A genetically inactivated herpes simplex virus type 2 (HSV-2) vaccine provides effective protection against primary and recurrent HSV-2 disease.

27 November 2017

cites work

1 reference

Disabled infectious single-cycle herpes simplex virus as an oncolytic vector for immunotherapy of colorectal cancer

21 January 2018

1 reference

Intratumoral recombinant GM-CSF-encoding virus as gene therapy in patients with cutaneous melanoma

21 January 2018

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Conditionally replicating herpes simplex virus mutant, G207 for the treatment of malignant glioma: results of a phase I trial

21 January 2018

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Toxicity evaluation of replication-competent herpes simplex virus (ICP 34.5 null mutant 1716) in patients with recurrent malignant glioma

21 January 2018

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Attenuated, replication-competent herpes simplex virus type 1 mutant G207: safety evaluation in mice

21 January 2018

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An analysis of 5'-noncoding sequences from 699 vertebrate messenger RNAs

21 January 2018

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Intranuclear foci containing low abundance herpes simplex virus latency-associated transcripts visualized by non-isotopic in situ hybridization

21 January 2018

1 reference

Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte-macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma

21 January 2018

1 reference

Persistent infection with herpes simplex virus type 1 in an Ia antigen-positive murine macrophage cell line

21 January 2018

1 reference

Herpes simplex encephalitis. Immunohistological demonstration of spread of virus via olfactory pathways in mice

21 January 2018

1 reference

Induction of encephalitis in SJL mice by intranasal infection with herpes simplex virus type 1: a possible model of herpes simplex encephalitis in humans

21 January 2018

1 reference

Repression of viral transcription during herpes simplex virus latency

21 January 2018

1 reference

Latent herpes simplex virus in spinal ganglia of mice

21 January 2018

1 reference

Mapping the in vivo distribution of herpes simplex virions

21 January 2018

1 reference

Biodistribution of an adenoviral vector carrying the luciferase reporter gene following intravesical or intravenous administration to a mouse

21 January 2018

1 reference

21 January 2018

Identifiers

DOI

10.1002/JGM.206

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27 November 2017

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