(Q43821450)

27 November 2017

title

A scintillation proximity assay for studying inhibitors of human tau protein kinase II/cdk5 using a 96-well format (English)

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27 November 2017

David B Evans

1

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27 November 2017

Kenneth B Rank

series ordinal

2

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27 November 2017

Satish K Sharma

series ordinal

3

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27 November 2017

publication date

1 January 2002

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27 November 2017

published in

Journal of Proteomics

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27 November 2017

volume

50

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27 November 2017

issue

2-3

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27 November 2017

page(s)

151-161

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Alzheimer plaques and tangles: advances on both fronts

27 November 2017

cites work

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Accumulation of abnormally phosphorylated tau precedes the formation of neurofibrillary tangles in Alzheimer's disease

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Tau protein and the neurofibrillary pathology of Alzheimer's disease

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A preparation of Alzheimer paired helical filaments that displays distinct tau proteins by polyacrylamide gel electrophoresis

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7 January 2021

Structural stability of paired helical filaments requires microtubule-binding domains of Tau: A model for self-association

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A68: a major subunit of paired helical filaments and derivatized forms of normal Tau.

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Tau protein function in living cells

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7 January 2021

Multiple isoforms of human microtubule-associated protein tau: sequences and localization in neurofibrillary tangles of Alzheimer's disease

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7 January 2021

Tau protein and Alzheimer's disease

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7 January 2021

Phosphorylation that detaches tau protein from microtubules (Ser262, Ser214) also protects it against aggregation into Alzheimer paired helical filaments

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7 January 2021

The cdk5/p35 kinase is essential for neurite outgrowth during neuronal differentiation

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7 January 2021

Evidence for the participation of the neuron-specific CDK5 activator P35 during laminin-enhanced axonal growth.

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7 January 2021

Tau phosphorylation at serine 396 and serine 404 by human recombinant tau protein kinase II inhibits tau's ability to promote microtubule assembly

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7 January 2021

Hyperphosphorylated tau and neurofilament and cytoskeletal disruptions in mice overexpressing human p25, an activator of cdk5

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7 January 2021

Phosphorylation of DARPP-32 by Cdk5 modulates dopamine signalling in neurons

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7 January 2021

Regulation of exocytosis by cyclin-dependent kinase 5 via phosphorylation of Munc18

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7 January 2021

Phosphorylation of human high molecular weight neurofilament protein (hNF-H) by neuronal cyclin-dependent kinase 5 (cdk5)

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7 January 2021

Phosphorylation of the high molecular weight neurofilament protein (NF-H) by Cdk5 and p35

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7 January 2021

Conversion of p35 to p25 deregulates Cdk5 activity and promotes neurodegeneration

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7 January 2021

p35 is a neural-specific regulatory subunit of cyclin-dependent kinase 5

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7 January 2021

A brain-specific activator of cyclin-dependent kinase 5.

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7 January 2021

Identification of the 23 kDa subunit of tau protein kinase II as a putative activator of cdk5 in bovine brain

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7 January 2021

Interaction of cyclin-dependent kinase 5 (Cdk5) and neuronal Cdk5 activator in bovine brain.

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7 January 2021

New phosphorylation sites identified in hyperphosphorylated tau (paired helical filament-tau) from Alzheimer's disease brain using nanoelectrospray mass spectrometry

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7 January 2021

Characterization of the in vitro phosphorylation of human tau by tau protein kinase II (cdk5/p20) using mass spectrometry

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7 January 2021

Neuronal Cdc2-like kinase: from cell cycle to neuronal function

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7 January 2021

10.1016/S0165-022X(01)00184-1

Identifiers

DOI

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27 November 2017

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