(Q43821570)

27 November 2017

title

Syntheses of fused heterocyclic compounds and their inhibitory activities for squalene synthase (English)

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27 November 2017

Takashi Miki

1

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27 November 2017

Masakuni Kori

2

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27 November 2017

Akira Fujishima

3

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27 November 2017

Hiroshi Mabuchi

4

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27 November 2017

Ryu ichi Tozawa

5

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27 November 2017

Masahira Nakamura

6

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27 November 2017

Yasuo Sugiyama

7

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27 November 2017

Hidefumi Yukimasa

8

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27 November 2017

language of work or name

English

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publication date

1 February 2002

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Bioorganic & Medicinal Chemistry

27 November 2017

published in

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27 November 2017

volume

10

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27 November 2017

issue

2

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27 November 2017

page(s)

385-400

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Consensus conference. Lowering blood cholesterol to prevent heart disease

27 November 2017

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Mevinolin: a highly potent competitive inhibitor of hydroxymethylglutaryl-coenzyme A reductase and a cholesterol-lowering agent

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Myotonia induced by diazacholesterol: increased (Na+ + K+)-ATPase activity of erythrocyte ghosts and development of cataracts

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7 January 2021

Inhibitors of squalene biosynthesis and metabolism

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7 January 2021

Combating cholesterol

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7 January 2021

The squalestatins: decarboxy and 4-deoxy analogues as potent squalene synthase inhibitors

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7 January 2021

The squalestatins: inhibitors of squalene synthase. Enzyme inhibitory activities and in vivo evaluation of C3-modified analogues

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Truncation of human squalene synthase yields active, crystallizable protein

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7 January 2021

Crystal structure of human squalene synthase. A key enzyme in cholesterol biosynthesis

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The benzodiazepine story

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Benzodiazepine gastrin and brain cholecystokinin receptor ligands: L-365,260.

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An opioid benzodiazepine

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Platelet-Activating Factor-Induced Aggregation of Human Platelets Specifically Inhibited by Triazolobenzodiazepines

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Inhibition of HIV replication in acute and chronic infections in vitro by a Tat antagonist

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7 January 2021

Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives

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7 January 2021

Benzodiazepine peptidomimetics: potent inhibitors of Ras farnesylation in animal cells

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Agonist regulation of cellular G protein levels and distribution: mechanisms and functional implications

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Synthesis and biological properties of (carboxyalkyl)amino-substituted bicyclic lactam inhibitors of angiotensin converting enzyme

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A novel 3-substituted benzazepinone growth hormone secretagogue (L-692,429)

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(+/-)-4-Aryl-4,5-dihydro-3H-1,3-benzodiazepines. 1. Synthesis and evaluation of (+/-)-4,5-dihydro-2,3-dimethyl-4-phenyl-3H-1,3-benzodiazepine and analogues as potential antidepressant agents

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(+/-)-4-Aryl-4,5-dihydro-3H-1,3-benzodiazepines. 2. Nuclear-substituted analogues of (+/-)-4,5-dihydro-2,3-dimethyl-4-phenyl-3H-1,3-benzodiazepine and (+/-)-4,5-dihydro-2-ethyl-3-methyl-4-phenyl-3H-1,3-benzodiazepine as potential antidepressant agen

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7 January 2021

Synthesis and angiotensin converting enzyme inhibitory activity of 1,5-benzothiazepine and 1,5-benzoxazepine derivatives. I

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7 January 2021

Extension of the Modified Stobbe Condensation. Acid-Catalyzed Decomposition of the Products and a Lacto—Enoic Tautomerism1

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7 January 2021

Nontricyclic antidepressant agents derived from cis- and trans-1-amino-4-aryltetralins

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7 January 2021

Benzazepinones. Synthesis of the monoaza analog of diazepam, and the correct structure of the benzoylpropionanilide cyclization product

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7 January 2021

Potent NK1 receptor antagonists: synthesis and antagonistic activity of various heterocycles with an N-[3,5-bis(trifluoromethyl)benzyl]-N-methylcarbamoyl substituent.

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7 January 2021

Synthesis of 3-Ureido Derivatives of Coumarin and 2-Quinolone as Potent Acyl-CoA: Cholesterol Acyltransferase Inhibitors

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7 January 2021

Regulation of squalene synthetase activity in rat liver: elevation by cholestyramine, but no diurnal variation

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7 January 2021

Synthesis of allylic and homoallylic isoprenoid pyrophosphates

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7 January 2021

10.1016/S0968-0896(01)00289-9

Identifiers

DOI

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27 November 2017

1 reference