(Q43823127)

27 November 2017

title

Selective mGluR5 receptor antagonist or agonist provides neuroprotection in a rat model of focal cerebral ischemia (English)

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27 November 2017

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W L Bao

1

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27 November 2017

A J Williams

series ordinal

2

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27 November 2017

A I Faden

series ordinal

3

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27 November 2017

F C Tortella

series ordinal

4

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27 November 2017

language of work or name

English

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publication date

1 December 2001

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27 November 2017

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27 November 2017

volume

922

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27 November 2017

issue

2

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27 November 2017

page(s)

173-179

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Activation of group I metabotropic glutamate receptors reduces neuronal apoptosis but increases necrotic cell death in vitro

27 November 2017

cites work

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Neuroprotective activity of the potent and selective mGlu1a metabotropic glutamate receptor antagonist, (+)-2-methyl-4 carboxyphenylglycine (LY367385): comparison with LY357366, a broader spectrum antagonist with equal affinity for mGlu1a and mGlu5 r

7 January 2021

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The metabotropic glutamate receptor mGlu5 controls the onset of developmental apoptosis in cultured cerebellar neurons

7 January 2021

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(RS)-2-chloro-5-hydroxyphenylglycine (CHPG) activates mGlu5, but no mGlu1, receptors expressed in CHO cells and potentiates NMDA responses in the hippocampus

7 January 2021

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Selective blockade of the mGluR1 receptor reduces traumatic neuronal injury in vitro and improvesoOutcome after brain trauma

7 January 2021

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2-Methyl-6-(phenylethynyl)-pyridine (MPEP), a potent, selective and systemically active mGlu5 receptor antagonist

7 January 2021

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Metabotropic glutamate receptors: novel targets for drug development

7 January 2021

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Brain tissue responses to ischemia

7 January 2021

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Intact, injured, necrotic and apoptotic cells after focal cerebral ischemia in the rat.

7 January 2021

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Activation of metabotropic glutamate receptor subtype mGluR1 contributes to post-traumatic neuronal injury

7 January 2021

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mGluR modulation of post-traumatic neuronal death: role of NMDA receptors

7 January 2021

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Group-I metabotropic glutamate receptors: hypotheses to explain their dual role in neurotoxicity and neuroprotection.

7 January 2021

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Selective mGluR5 antagonists MPEP and SIB-1893 decrease NMDA or glutamate-mediated neuronal toxicity through actions that reflect NMDA receptor antagonism

7 January 2021

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The non-competitive antagonists 2-methyl-6-(phenylethynyl)pyridine and 7-hydroxyiminocyclopropan[b]chromen-1a-carboxylic acid ethyl ester interact with overlapping binding pockets in the transmembrane region of group I metabotropic glutamate recepto

7 January 2021

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Protection with metabotropic glutamate 1 receptor antagonists in models of ischemic neuronal death: time-course and mechanisms

7 January 2021

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The metabotropic glutamate receptors: structure and functions

7 January 2021

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Pharmacological agents acting at subtypes of metabotropic glutamate receptors

7 January 2021

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Pharmacology of AMPA antagonists and their role in neuroprotection

7 January 2021

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10.1016/S0006-8993(01)03062-1

7 January 2021

Identifiers

DOI

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27 November 2017

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