(Q43829355)

27 November 2017

title

Mechanisms of tolerance to DNA damaging therapeutic drugs (English)

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27 November 2017

Karran P

1

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27 November 2017

language of work or name

English

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publication date

1 December 2001

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27 November 2017

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27 November 2017

volume

22

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27 November 2017

issue

12

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27 November 2017

page(s)

1931-1937

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Mammalian DNA mismatch repair

27 November 2017

cites work

1 reference

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The barrier to recombination between Escherichia coli and Salmonella typhimurium is disrupted in mismatch-repair mutants

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Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer

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Increased somatic recombination in methylation tolerant human cells with defective DNA mismatch repair

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Repair of double-strand breaks by homologous recombination in mismatch repair-defective mammalian cells

21 January 2018

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DNA damage tolerance, mismatch repair and genome instability

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An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair.

21 January 2018

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Induced mutagenesis in dam − mutants of Escherichia coli: A role for 6-methyladenine residues in mutation avoidance

21 January 2018

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Mismatch repair in correction of replication errors and processing of DNA damage

21 January 2018

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Role of postreplicative DNA mismatch repair in the cytotoxic action of thioguanine.

21 January 2018

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Recombination is essential for viability of an Escherichia coli dam (DNA adenine methyltransferase) mutant

21 January 2018

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Mismatch repair proteins MutS and MutL inhibit RecA-catalyzed strand transfer between diverged DNAs

21 January 2018

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Human MutSalpha recognizes damaged DNA base pairs containing O6-methylguanine, O4-methylthymine, or the cisplatin-d(GpG) adduct

21 January 2018

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21 January 2018

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Dependence on RAD52 and RAD1 for anticancer drug resistance mediated by inactivation of mismatch repair genes.

21 January 2018

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DNA mismatch repair mutants do not increase N-methyl-N'-nitro- N-nitrosoguanidine tolerance in O6-methylguanine DNA methyltransferase-deficient yeast cells

21 January 2018

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21 January 2018

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21 January 2018

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Mismatch repair processing of carcinogen-DNA adducts triggers apoptosis

21 January 2018

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21 January 2018

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All three SOS-inducible DNA polymerases (Pol II, Pol IV and Pol V) are involved in induced mutagenesis

21 January 2018

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Why do O6-alkylguanine and O4-alkylthymine miscode? The relationship between the structure of DNA containing O6-alkylguanine and O4-alkylthymine and the mutagenic properties of these bases

21 January 2018

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21 January 2018

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Self-destruction and tolerance in resistance of mammalian cells to alkylation damage

21 January 2018

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Role of DNA mismatch repair and p53 in signaling induction of apoptosis by alkylating agents.

21 January 2018

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The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage

21 January 2018

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p73 is regulated by tyrosine kinase c-Abl in the apoptotic response to DNA damage

21 January 2018

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Competency in mismatch repair prohibits clonal expansion of cancer cells treated with N-methyl-N'-nitro-N-nitrosoguanidine

21 January 2018

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Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

21 January 2018

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Growth inhibition due to complementation of transforming growth factor-beta receptor type II-defect by human chromosome 3 transfer in human colorectal carcinoma cells

21 January 2018

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Separation of killing and tumorigenic effects of an alkylating agent in mice defective in two of the DNA repair genes

21 January 2018

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Characterization of MLH1 and MSH2 DNA mismatch repair proteins in cell lines of the NCI anticancer drug screen

21 January 2018

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Cisplatin and adriamycin resistance are associated with MutLalpha and mismatch repair deficiency in an ovarian tumor cell line

21 January 2018

1 reference

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Cytotoxic and mutagenic response of mismatch repair-defective human cancer cells exposed to a food-associated heterocyclic amine.

21 January 2018

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Carcinogen-specific induction of genetic instability.

21 January 2018

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Mismatch repair defects as a cause of resistance to cytotoxic drugs

21 January 2018

1 reference

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Cellular resistance and hypermutability in mismatch repair-deficient human cancer cell lines following treatment with methyl methanesulfonate.

21 January 2018

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Differential growth inhibition by 5-fluorouracil in human colorectal carcinoma cell lines.

21 January 2018

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Human MutSα Specifically Binds to DNA Containing Aminofluorene and Acetylaminofluorene Adducts

21 January 2018

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Mismatch correction at O 6 -methylguanine residues in E. coli DNA

21 January 2018

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10.1093/CARCIN/22.12.1931

21 January 2018

Identifiers

DOI

1 reference

27 November 2017

1 reference