(Q43835761)

27 November 2017

title

Interleukin-10 deficiency aggravates kidney inflammation and fibrosis in the unilateral ureteral obstruction mouse model (English)

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27 November 2017

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Yuanmeng Jin

1

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27 November 2017

Ruijie Liu

2

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27 November 2017

Jingyuan Xie

3

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27 November 2017

Huabao Xiong

4

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27 November 2017

John Cijiang He

5

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27 November 2017

Nan Chen

6

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27 November 2017

language of work or name

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29 April 2013

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27 November 2017

published in

Laboratory Investigation

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27 November 2017

volume

93

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27 November 2017

issue

7

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27 November 2017

page(s)

801-811

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https://scigraph.springernature.com/pub.10.1038/labinvest.2013.64

27 November 2017

exact match

0 references

cites work

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Interleukin 10 (IL-10) and viral IL-10 strongly reduce antigen-specific human T cell proliferation by diminishing the antigen-presenting capacity of monocytes via downregulation of class II major histocompatibility complex expression

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Electroporative interleukin-10 gene transfer ameliorates carbon tetrachloride-induced murine liver fibrosis by MMP and TIMP modulation

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Long-term interleukin 10 therapy in chronic hepatitis C patients has a proviral and anti-inflammatory effect.

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Introduction of the interleukin-10 gene into mice inhibited bleomycin-induced lung injury in vivo

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Endogenous interleukin-10 modulates fibrosis and regeneration in experimental chronic pancreatitis

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Adeno-associated virus vector-mediated systemic interleukin-10 expression ameliorates hypertensive organ damage in Dahl salt-sensitive rats

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Interleukin-10 regulates transforming growth factor-beta signaling in cultured human bronchial epithelial cells

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IL-10 suppresses chemokines, inflammation, and fibrosis in a model of chronic renal disease

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IL-10/TGF-beta-modified macrophages induce regulatory T cells and protect against adriamycin nephrosis.

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Adipose tissue-derived stem cell treatment prevents renal disease progression.

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Interleukin-10-deficient mice develop chronic enterocolitis

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Interleukin-10 is a central regulator of the response to LPS in murine models of endotoxic shock and the Shwartzman reaction but not endotoxin tolerance.

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Multisystemic production of interleukin 10 limits the severity of acute pancreatitis in mice

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7 January 2021

Leukocyte-derived IL-10 reduces subepithelial fibrosis associated with chronically inhaled endotoxin

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In vivo IL-10 gene delivery attenuates bleomycin induced pulmonary fibrosis by inhibiting the production and activation of TGF-beta in the lung.

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7 January 2021

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7 January 2021

10.1038/LABINVEST.2013.64

Identifiers

DOI

1 reference

27 November 2017

1 reference