(Q43862884)

27 November 2017

title

The catalytic mechanism of Cdc25A phosphatase (English)

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27 November 2017

2

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27 November 2017

3

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27 November 2017

Daniel F McCain

1

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27 November 2017

Zhong-Yin Zhang

series ordinal

4

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27 November 2017

language of work or name

English

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publication date

22 January 2002

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Journal of Biological Chemistry

27 November 2017

published in

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27 November 2017

volume

277

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27 November 2017

issue

13

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27 November 2017

page(s)

11190-11200

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27 November 2017

cites work

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Cell cycle regulation by the Cdc25 phosphatase family

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Role of the Cdc25A phosphatase in human breast cancer

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Dual G1 and G2/M phase inhibition by SC-alpha alpha delta 9, a combinatorially derived Cdc25 phosphatase inhibitor

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Syntheses and biological activities of a novel group of steroidal derived inhibitors for human Cdc25A protein phosphatase

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Cyclin-dependent kinases: engines, clocks, and microprocessors

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The cdc25 protein contains an intrinsic phosphatase activity

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cdc25 is a specific tyrosine phosphatase that directly activates p34cdc2.

21 January 2018

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Dephosphorylation and activation of a p34cdc2/cyclin B complex in vitro by human CDC25 protein

21 January 2018

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Cloning, expression, and catalytic mechanism of the low molecular weight phosphotyrosyl protein phosphatase from bovine heart

21 January 2018

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Visualization of intermediate and transition-state structures in protein-tyrosine phosphatase catalysis

21 January 2018

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Protein-tyrosine phosphatases: biological function, structural characteristics, and mechanism of catalysis

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The mechanism of dephosphorylation of extracellular signal-regulated kinase 2 by mitogen-activated protein kinase phosphatase 3.

21 January 2018

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The Cys(X)5Arg catalytic motif in phosphoester hydrolysis

21 January 2018

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Impaired transition state complementarity in the hydrolysis of O-arylphosphorothioates by protein-tyrosine phosphatases.

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Roles of active site residues and the NH2-terminal domain in the catalysis and substrate binding of human Cdc25

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Dissecting the catalytic mechanism of protein-tyrosine phosphatases

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Nature of the transition state of the protein-tyrosine phosphatase-catalyzed reaction

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Probing the function of Asp128 in the lower molecular weight protein-tyrosine phosphatase-catalyzed reaction. A pre-steady-state and steady-state kinetic investigation

21 January 2018

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Transition state analysis and requirement of Asp-262 general acid/base catalyst for full activation of dual-specificity phosphatase MKP3 by extracellular regulated kinase

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Structure-based design of a low molecular weight, nonphosphorus, nonpeptide, and highly selective inhibitor of protein-tyrosine phosphatase 1B

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Development of "substrate-trapping" mutants to identify physiological substrates of protein tyrosine phosphatases

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Identification of an essential acidic residue in Cdc25 protein phosphatase and a general three-dimensional model for a core region in protein phosphatases

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A model of Cdc25 phosphatase catalytic domain and Cdk-interaction surface based on the presence of a rhodanese homology domain

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Crystal structure of the catalytic domain of the human cell cycle control phosphatase, Cdc25A

21 January 2018

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Crystal structure of the catalytic subunit of Cdc25B required for G2/M phase transition of the cell cycle

21 January 2018

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Leaving group dependence in the phosphorylation of Escherichia coli alkaline phosphatase by monophosphate esters.

21 January 2018

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Inorganic phosphate determination in the presence of a labile organic phosphate: Assay for carbamyl phosphate phosphatase activity

21 January 2018

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A continuous spectrophotometric and fluorimetric assay for protein tyrosine phosphatase using phosphotyrosine-containing peptides

21 January 2018

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Transition-state structures for enzymatic and alkaline phosphotriester hydrolysis.

21 January 2018

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Crystal structure of Yersinia protein tyrosine phosphatase at 2.5 A and the complex with tungstate

21 January 2018

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Crystal structure of human protein tyrosine phosphatase 1B

21 January 2018

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Structural basis for phosphotyrosine peptide recognition by protein tyrosine phosphatase 1B

21 January 2018

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Structural basis of plasticity in protein tyrosine phosphatase 1B substrate recognition

21 January 2018

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The crystal structure of a low-molecular-weight phosphotyrosine protein phosphatase

21 January 2018

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Crystal structures of a low-molecular weight protein tyrosine phosphatase from Saccharomyces cerevisiae and its complex with the substrate p-nitrophenyl phosphate

21 January 2018

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Crystal structure of the dual specificity protein phosphatase VHR

21 January 2018

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Crystal structure of bovine heart phosphotyrosyl phosphatase at 2.2-A resolution

21 January 2018

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Catalytic function of the conserved hydroxyl group in the protein tyrosine phosphatase signature motif.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M109636200

A catalytic mechanism for the dual-specific phosphatases

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M109636200

Kinetic and mechanistic characterization of a mammalian protein-tyrosine phosphatase, PTP1.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M109636200

Altering the nucleophile specificity of a protein-tyrosine phosphatase-catalyzed reaction. Probing the function of the invariant glutamine residues

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M109636200

VHR and PTP1 protein phosphatases exhibit remarkably different active site specificities toward low molecular weight nonpeptidic substrates

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M109636200

Kinetic analysis of the catalytic domain of human cdc25B.

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M109636200

Active site labeling of the Yersinia protein tyrosine phosphatase: the determination of the pKa of the active site cysteine and the function of the conserved histidine 402.

21 January 2018

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Multiple regions of MAP kinase phosphatase 3 are involved in its recognition and activation by ERK2.

21 January 2018

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Aspartic-129 is an essential residue in the catalytic mechanism of the low M r phosphotyrosine protein phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109636200

cdc25a and the splicing variant cdc25b2, but not cdc25B1, -B3 or -C, are over-expressed in aggressive human non-Hodgkin's lymphomas

21 January 2018

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Differential expression of cdc25 cell-cycle-activating phosphatases in human colorectal carcinoma

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M109636200

Vitamin K3 induces cell cycle arrest and cell death by inhibiting Cdc25 phosphatase

21 January 2018

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Synthesis of the novel analogues of dysidiolide and their structure-activity relationship

21 January 2018

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The role of Cys12, Cys17 and Arg18 in the catalytic mechanism of low-M(r) cytosolic phosphotyrosine protein phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109636200

Roles of aspartic acid-181 and serine-222 in intermediate formation and hydrolysis of the mammalian protein-tyrosine-phosphatase PTP1

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109636200

The catalytic role of aspartic acid-92 in a human dual-specific protein-tyrosine-phosphatase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109636200

Transition-state structures for the native dual-specific phosphatase VHR and D92N and S131A mutants. Contributions to the driving force for catalysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109636200

Reactivity of alcohols toward the phosphoenzyme intermediate in the protein-tyrosine phosphatase-catalyzed reaction: probing the transition state of the dephosphorylation step

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109636200

Examination of the transition state of the low-molecular mass small tyrosine phosphatase 1. Comparisons with other protein phosphatases

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109636200

Leaving group dependence and proton inventory studies of the phosphorylation of a cytoplasmic phosphotyrosyl protein phosphatase from bovine heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109636200

Transition state and rate-limiting step of the reaction catalyzed by the human dual-specificity phosphatase, VHR

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109636200

Mechanism of mitogen-activated protein kinase phosphatase-3 activation by ERK2

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109636200

Mechanistic basis for catalytic activation of mitogen-activated protein kinase phosphatase 3 by extracellular signal-regulated kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109636200

Dual-specific Cdc25B phosphatase: in search of the catalytic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109636200

21 January 2018

Identifiers

DOI

10.1074/JBC.M109636200

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27 November 2017

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