(Q43877164)

27 November 2017

Regulation of Lck activity by CD4 and CD28 in the immunological synapse (English)

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27 November 2017

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27 November 2017

5

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27 November 2017

Kyeong-Hee Lee

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27 November 2017

W Richard Burack

series ordinal

3

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27 November 2017

Paul M Allen

series ordinal

4

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27 November 2017

language of work or name

English

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publication date

4 February 2002

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27 November 2017

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27 November 2017

259-264

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27 November 2017

3

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https://scigraph.springernature.com/pub.10.1038/ni761

27 November 2017

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cites work

Information transfer at the immunological synapse.

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7 January 2021

T cell receptor-mediated signs and signals governing T cell development

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7 January 2021

The CD45 tyrosine phosphatase: a positive and negative regulator of immune cell function

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7 January 2021

Expression of CD45 alters phosphorylation of the lck-encoded tyrosine protein kinase in murine lymphoma T-cell lines

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7 January 2021

Correlation between Src family member regulation by the protein-tyrosine-phosphatase CD45 and transmembrane signaling through the T-cell receptor

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7 January 2021

Interactions of TCR tyrosine based activation motifs with tyrosine kinases.

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7 January 2021

Reciprocal regulation of Hck activity by phosphorylation of Tyr(527) and Tyr(416). Effect of introducing a high affinity intramolecular SH2 ligand

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7 January 2021

Activation of the Src-family tyrosine kinase Hck by SH3 domain displacement

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7 January 2021

Proline residues in CD28 and the Src homology (SH)3 domain of Lck are required for T cell costimulation

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7 January 2021

Structural requirements for enhancement of T-cell responsiveness by the lymphocyte-specific tyrosine protein kinase p56lck

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7 January 2021

Crystal structure of Hck in complex with a Src family-selective tyrosine kinase inhibitor

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7 January 2021

Crystal structures of c-Src reveal features of its autoinhibitory mechanism

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7 January 2021

Association of the fyn protein-tyrosine kinase with the T-cell antigen receptor

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7 January 2021

Activation of human peripheral blood T lymphocytes by pharmacological induction of protein-tyrosine phosphorylation

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7 January 2021

Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor

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7 January 2021

Induction by antigen of intrathymic apoptosis of CD4+CD8+TCRlo thymocytes in vivo

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7 January 2021

Structural basis for T cell recognition of altered peptide ligands: a single T cell receptor can productively recognize a large continuum of related ligands

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7 January 2021

The immunological synapse: a molecular machine controlling T cell activation

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7 January 2021

T cell antigen receptor activation pathways: The tyrosine kinase connection

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7 January 2021

Alterations of the lymphocyte-specific protein tyrosine kinase (p56lck) during T-cell activation

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7 January 2021

The lymphocyte-specific protein tyrosine kinase p56lck is hyperphosphorylated on serine and tyrosine residues within minutes after activation via T cell receptor or CD2

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7 January 2021

The CD4 and CD8 T cell surface antigens are associated with the internal membrane tyrosine-protein kinase p56lck

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7 January 2021

Alterations in tyrosine protein phosphorylation induced by antibody-mediated cross-linking of the CD4 receptor of T lymphocytes

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7 January 2021

Cross-linking of T-cell surface molecules CD4 and CD8 stimulates phosphorylation of the lck tyrosine protein kinase at the autophosphorylation site

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7 January 2021

Molecular Analysis of the Interaction of p56lck with the CD4 and CD8 Antigens

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7 January 2021

Signal transduction by CD28 costimulatory receptor on T cells. B7-1 and B7-2 regulation of tyrosine kinase adaptor molecules

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7 January 2021

T lymphocyte costimulation mediated by reorganization of membrane microdomains

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7 January 2021

The catalytic activity of the CD45 membrane-proximal phosphatase domain is required for TCR signaling and regulation

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7 January 2021

Dynamic coupling between the SH2 and SH3 domains of c-Src and Hck underlies their inactivation by C-terminal tyrosine phosphorylation

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7 January 2021

Tyrosine phosphatase CD45 is required for T-cell antigen receptor and CD2-mediated activation of a protein tyrosine kinase and interleukin 2 production

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7 January 2021

Interaction of CD4:lck with the T cell receptor/CD3 complex induces early signaling events in the absence of CD45 tyrosine phosphatase

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7 January 2021

Coordinate regulation of T cell activation by CD2 and CD28

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7 January 2021

Three-dimensional segregation of supramolecular activation clusters in T cells

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7 January 2021

Differential clustering of CD4 and CD3zeta during T cell recognition

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7 January 2021

The immunological synapse and CD28-CD80 interactions.

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7 January 2021

Lck activity controls CD4/CD8 T cell lineage commitment.

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7 January 2021

Partial T cell signaling: altered phospho-zeta and lack of zap70 recruitment in APL-induced T cell anergy

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7 January 2021

Fidelity of T cell activation through multistep T cell receptor zeta phosphorylation

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7 January 2021

The immunological synapse.

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7 January 2021

The TCR triggering puzzle

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7 January 2021

CD8 Expression Allows T Cell Signaling by Monomeric Peptide-MHC Complexes

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7 January 2021

Monomeric class I molecules mediate TCR/CD3 epsilon/CD8 interaction on the surface of T cells

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7 January 2021

Identifiers

DOI

10.1038/NI761

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Dimensions Publication ID

27 November 2017

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