(Q43911240)

English

9-Carboxymethyl-5H,10H-imidazo[1,2-a]indeno[1,2-e]pyrazin-4-one-2-carbocylic acid (RPR117824): selective anticonvulsive and neuroprotective AMPA antagonist.

scientific article published in May 2002

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11886824%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

9-Carboxymethyl-5H,10H-imidazo[1,2-a]indeno[1,2-e]pyrazin-4-one-2-carbocylic acid (RPR117824): selective anticonvulsive and neuroprotective AMPA antagonist (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11886824%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11886824%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

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Georg Andrees Bohme

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11886824%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

Guillaume Birraux

3

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11886824%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

Alain Boireau

4

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11886824%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

Patrick Jimonet

5

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8 December 2019

Dominique Damour

6

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8 December 2019

Arielle Genevois-Borella

7

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8 December 2019

Marc Williams Debono

8

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8 December 2019

Jeremy Pratt

9

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8 December 2019

Marc Vuilhorgne

10

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8 December 2019

Florence Wahl

11

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8 December 2019

Jean Marie Stutzmann

12

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8 December 2019

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1 May 2002

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8 December 2019

Bioorganic & Medicinal Chemistry

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8 December 2019

10

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8 December 2019

5

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8 December 2019

1627-1637

1 reference

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PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11886824%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

Molecular diversity of glutamate receptors and implications for brain function

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Global ischemia induces downregulation of Glur2 mRNA and increases AMPA receptor-mediated Ca2+ influx in hippocampal CA1 neurons of gerbil

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AMPA receptor antagonists

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2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a neuroprotectant for cerebral ischemia

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6-(1H-imidazol-1-yl)-7-nitro-2,3(1H,4H)-quinoxalinedione hydrochloride (YM90K) and related compounds: structure-activity relationships for the AMPA-type non-NMDA receptor

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(3SR,4aRS,6RS,8aRS)-6-[2-(1H-tetrazol-5-yl)ethyl]decahydroisoquinoline-3 - carboxylic acid: a structurally novel, systemically active, competitive AMPA receptor antagonist.

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Spiro-imidazo[1,2-a]indeno[1,2-e]pyrazine-4-one derivatives are mixed AMPA and NMDA glycine-site antagonists active in vivo

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8-Methylureido-4,5-dihydro-4-oxo-10H-imidazo[1,2-a]indeno[1,2-e]pyrazines: highly potent in vivo AMPA antagonists

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4,10-Dihydro-4-oxo-4H-imidazo[1,2-a]indeno[1,2-e]pyrazin-2-carboxylic acid derivatives: highly potent and selective AMPA receptors antagonists with in vivo activity

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Synthesis and potent anticonvulsant activities of 4-oxo-imidazo[1,2-a]inden.

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Bioisosteres of 9-carboxymethyl-4-oxo-imidazo[1,2-a]indeno-[1,2-e]pyrazin-2-carboxylic acid derivatives. Progress towards selective, potent in vivo AMPA antagonists with longer durations of action.

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Focal Cerebral Ischaemia in the Rat: 1. Description of Technique and Early Neuropathological Consequences following Middle Cerebral Artery Occlusion

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Identifiers

10.1016/S0968-0896(01)00431-X

1 reference

Europe PubMed Central

PubMed publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11886824%20AND%20SRC:MED&resulttype=core&format=json

8 December 2019

release_6vbbmnx4qvdpjl6dtqabujdzk4

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PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

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8 December 2019

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