(Q43916572)

28 November 2017

title

Peptidyl alpha-keto amide inhibitor of calpain blocks excitotoxic damage without affecting signal transduction events (English)

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28 November 2017

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Ebru Caba

1

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28 November 2017

Queenie B Brown

series ordinal

2

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28 November 2017

Brian Kawasaki

series ordinal

3

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28 November 2017

Ben A Bahr

series ordinal

4

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28 November 2017

publication date

1 March 2002

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Journal of Neuroscience Research

28 November 2017

published in

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28 November 2017

volume

67

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28 November 2017

issue

6

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28 November 2017

page(s)

787-794

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Regional differences in the activation of synaptosomal mitochondrial Ca2+ uptake by spermine in rat brain

28 November 2017

cites work

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Disruption of the murine calpain small subunit gene, Capn4: calpain is essential for embryonic development but not for cell growth and division

21 January 2018

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Disruption of the mouse mu-calpain gene reveals an essential role in platelet function

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Integrin-type signaling has a distinct influence on NMDA-induced cytoskeletal disassembly.

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Induction of beta-amyloid-containing polypeptides in hippocampus: evidence for a concomitant loss of synaptic proteins and interactions with an excitotoxin

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Stable maintenance of glutamate receptors and other synaptic components in long-term hippocampal slices

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Distinct distributions of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptor subunits and a related 53,000 M(R) antigen (GR53) in brain tissue.

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Amyloid beta protein is internalized selectively by hippocampal field CA1 and causes neurons to accumulate amyloidogenic carboxyterminal fragments of the amyloid precursor protein

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Postischemic administration of AK275, a calpain inhibitor, provides substantial protection against focal ischemic brain damage

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Translational suppression of calpain I reduces NMDA-induced spectrin proteolysis and pathophysiology in cultured hippocampal slices

21 January 2018

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Regional distribution and time-course of calpain activation following kainate-induced seizure activity in adult rat brain

21 January 2018

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Calpain-mediated proteolysis of GluR1 subunits in organotypic hippocampal cultures following kainic acid treatment.

21 January 2018

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Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms

21 January 2018

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Focal adhesion kinase (pp125FAK) cleavage and regulation by calpain

21 January 2018

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Calpain inhibition protects against virus-induced apoptotic myocardial injury

21 January 2018

1 reference

Stimulation of NMDA receptors activates calpain in cultured hippocampal slices

21 January 2018

1 reference

Evidence that activation of platelet calpain is induced as a consequence of binding of adhesive ligand to the integrin, glycoprotein IIb-IIIa

21 January 2018

1 reference

Neuroprotection with a calpain inhibitor in a model of focal cerebral ischemia

21 January 2018

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Regulation of cell migration by the calcium-dependent protease calpain

21 January 2018

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Examination of DNA-binding activity of neuronal transcription factors by electrophoretical mobility shift assay

21 January 2018

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Variants of the receptor/channel clustering molecule gephyrin in brain: distinct distribution patterns, developmental profiles, and proteolytic cleavage by calpain

21 January 2018

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Neurturin, a relative of glial-cell-line-derived neurotrophic factor

21 January 2018

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Inhibition of proteolysis protects hippocampal neurons from ischemia

21 January 2018

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Novel peptidyl alpha-keto amide inhibitors of calpains and other cysteine proteases

21 January 2018

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Six-hour window of opportunity for calpain inhibition in focal cerebral ischemia in rats

21 January 2018

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Roles of nuclear factor kappaB in neuronal survival and plasticity

21 January 2018

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Calpain inhibitor I reduces the activation of nuclear factor-kappaB and organ injury/dysfunction in hemorrhagic shock

21 January 2018

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Calpain activity in the rat brain after transient forebrain ischemia

21 January 2018

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A calpain inhibitor attenuates cortical cytoskeletal protein loss after experimental traumatic brain injury in the rat.

21 January 2018

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Protective effects of calpain inhibitors against neuronal damage caused by cytotoxic hypoxia in vitro and ischemia in vivo

21 January 2018

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Calcium-dependent signaling pathways in T cells. Potential role of calpain, protein tyrosine phosphatase 1b, and p130Cas in integrin-mediated signaling events

21 January 2018

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Calpain inhibitor AK295 attenuates motor and cognitive deficits following experimental brain injury in the rat

21 January 2018

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Calcium, protease action, and the regulation of the cell cycle

21 January 2018

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Crucial role of the amino-terminal tyrosine residue 42 and the carboxyl-terminal PEST domain of I kappa B alpha in NF-kappa B activation by an oxidative stress

21 January 2018

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Rapid detection of octamer binding proteins with 'mini-extracts', prepared from a small number of cells

21 January 2018

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Activation of the extracellular signal-regulated protein kinase cascade in the hippocampal CA1 region in a rat model of global cerebral ischemic preconditioning

21 January 2018

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The PEST domain of IkappaBalpha is necessary and sufficient for in vitro degradation by mu-calpain

21 January 2018

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Life and death decisions: regulation of apoptosis by proteolysis of signaling molecules

21 January 2018

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Calpain inhibitor entrapped in liposome rescues ischemic neuronal damage

21 January 2018

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The calpain small subunit gene is essential: its inactivation results in embryonic lethality.

21 January 2018

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Calpain inhibitor AK295 protects neurons from focal brain ischemia. Effects of postocclusion intra-arterial administration

21 January 2018

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Delayed antagonism of calpain reduces excitotoxicity in cultured neurons

21 January 2018

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Peptide alpha-keto ester, alpha-keto amide, and alpha-keto acid inhibitors of calpains and other cysteine proteases

21 January 2018

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21 January 2018

Identifiers

DOI

10.1002/JNR.10163

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28 November 2017

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