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In vivo antioxidant role of glutathione peroxidase: evidence from knockout mice.
scientific article published in January 2002
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scholarly article
1 reference
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Europe PubMed Central
PubMed publication ID
11898410
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11898410%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
title
In vivo antioxidant role of glutathione peroxidase: evidence from knockout mice
(English)
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11898410
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11898410%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
main subject
knockout mouse
0 references
glutathione
1 reference
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inferred from title
author
Xin Gen Lei
series ordinal
1
1 reference
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Europe PubMed Central
PubMed publication ID
11898410
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11898410%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
author name string
Xin Gen Lei
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1
1 reference
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Europe PubMed Central
PubMed publication ID
11898410
retrieved
28 November 2017
language of work or name
English
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publication date
1 January 2002
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11898410
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11898410%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
published in
Methods in Enzymology
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stated in
Europe PubMed Central
PubMed publication ID
11898410
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11898410%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
volume
347
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11898410
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11898410%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
page(s)
213-225
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11898410
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11898410%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
cites work
SELENIUM AS AN INTEGRAL PART OF FACTOR 3 AGAINST DIETARY NECROTIC LIVER DEGENERATION
1 reference
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Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
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inferred from DOI database lookup
Selenium: Biochemical Role as a Component of Glutathione Peroxidase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glutathione peroxidase: a selenoenzyme
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of the catalytic site of rat liver glutathione peroxidase as selenocysteine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identification of selenocysteine in glutathione peroxidase by mass spectroscopy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Extracellular glutathione peroxidase mRNA and protein in human cell lines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selenium regulation of glutathione peroxidase in human hepatoma cell line Hep3B.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tissue-specific regulation of selenoenzyme gene expression during selenium deficiency in rats.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tissue specificity of selenoprotein gene expression in rats
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differential selenium-dependent expression of type I 5'-deiodinase and glutathione peroxidase in the porcine epithelial kidney cell line LLC-PK1.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The effect of progressive selenium deficiency on anti-glutathione peroxidase antibody reactive protein in rat liver
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Phospholipid hydroperoxide glutathione peroxidase in various mouse organs during selenium deficiency and repletion
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Dietary selenium intake controls rat plasma selenoprotein P concentration
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Distribution of selenium and glutathione peroxidase in the rat
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Tissue-specific functions of individual glutathione peroxidases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Bcl-2 functions in an antioxidant pathway to prevent apoptosis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Heterologous expression of selenium-dependent glutathione peroxidase affords cellular resistance to paraquat
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glutathione peroxidase protects cultured mammalian cells from the toxicity of adriamycin and paraquat
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mice deficient in cellular glutathione peroxidase develop normally and show no increased sensitivity to hyperoxia
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mice with a homozygous null mutation for the most abundant glutathione peroxidase, Gpx1, show increased susceptibility to the oxidative stress-inducing agents paraquat and hydrogen peroxide.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mitochondrial oxidative stress in mice lacking the glutathione peroxidase-1 gene
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Variation in cellular glutathione peroxidase activity in lens epithelial cells, transgenics and knockouts does not significantly change the response to H2O2 stress
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Overexpression of cellular glutathione peroxidase does not affect expression of plasma glutathione peroxidase or phospholipid hydroperoxide glutathione peroxidase in mice offered diets adequate or deficient in selenium
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular glutathione peroxidase knockout mice express normal levels of selenium-dependent plasma and phospholipid hydroperoxide glutathione peroxidases in various tissues
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Knockout of cellular glutathione peroxidase affects selenium-dependent parameters similarly in mice fed adequate and excessive dietary selenium.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Knockout of cellular glutathione peroxidase gene renders mice susceptible to diquat-induced oxidative stress
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selenium-dependent cellular glutathione peroxidase protects mice against a pro-oxidant-induced oxidation of NADPH, NADH, lipids, and protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Superoxide- and singlet oxygen-catalyzed lipid peroxidation as a possible mechanism for paraquat (methyl viologen) toxicity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Liver necrosis and lipid peroxidation in the rat as the result of paraquat and diquat administration. Effect of selenium deficiency
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protection against acute paraquat toxicity by dietary selenium in the chick
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selenium-dependent glutathione peroxidase inhibitors increase toxicity of prooxidant compounds in chicks
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Synthetic seleno-organic compound with glutathione peroxidase-like activity in the chick
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Liver damage following paraquat in selenium-deficient and diethyl maleate-pretreated mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cellular glutathione peroxidase is the mediator of body selenium to protect against paraquat lethality in transgenic mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Carbonyl assays for determination of oxidatively modified proteins.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vivo oxidation of reduced nicotinamide-adenine dinucleotide phosphate by paraquat and diquat in rat lung
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Analysis of oxidized and reduced pyridine dinucleotides in rat liver by high-performance liquid chromatography
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mass spectrometry of prostanoids: F2-isoprostanes produced by non-cyclooxygenase free radical-catalyzed mechanism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
On the mechanism of paraquat action on microsomal oxygen reduction and its relation to lipid peroxidation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Lipid peroxidation and paraquat toxicity
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High levels of dietary vitamin E do not replace cellular glutathione peroxidase in protecting mice from acute oxidative stress
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Effects of oxidative stress caused by hyperoxia and diquat. A study in isolated hepatocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Relationships between intracellular vitamin E, lipid peroxidation, and chemical toxicity in hepatocytes
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Microsomal lipid peroxidation: effect of vitamin E and its functional interaction with phospholipid hydroperoxide glutathione peroxidase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Peroxide-induced damage in lenses of transgenic mice with deficient and elevated levels of glutathione peroxidase
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The contribution of GSH peroxidase-1, catalase and GSH to the degradation of H2O2 by the mouse lens
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Mice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitropropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Preferential resistance of dopaminergic neurons to the toxicity of glutathione depletion is independent of cellular glutathione peroxidase and is mediated by tetrahydrobiopterin
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glutathione peroxidase protects mice from viral-induced myocarditis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glutathione peroxidase-deficient mice are more susceptible to neutrophil-mediated hepatic parenchymal cell injury during endotoxemia: importance of an intracellular oxidant stress
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Relationship between the critical level of oxidative stresses and the glutathione peroxidase activity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Decreased glutathione peroxidase activity in mice in response to nafenopin is caused by changes in selenium metabolism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glutathione Peroxidase Protects against Peroxynitrite-mediated Oxidations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Chronic brain oxidation in a glutathione peroxidase knockout mouse model results in increased resistance to induced epileptic seizures
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Deliberations and evaluations of the approaches, endpoints and paradigms for selenium and iodine dietary recommendations
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Glutathione Peroxidase, V. The kinetic mechanism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular biology of selenium with implications for its metabolism 1
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0076-6879%2802%2947021-8
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0076-6879(02)47021-8
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11898410
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11898410%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
PubMed publication ID
11898410
1 reference
stated in
Europe PubMed Central
PubMed publication ID
11898410
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:11898410%20AND%20SRC:MED&resulttype=core&format=json
retrieved
8 December 2019
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