(Q43923697)

28 November 2017

title

A multimodal, β-amyloid-targeted contrast agent (English)

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28 November 2017

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Sashiprabha M Vithanarachchi

series ordinal

1

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28 November 2017

Matthew J Allen

series ordinal

2

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28 November 2017

language of work or name

English

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publication date

9 November 2012

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28 November 2017

number of pages

3

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based on heuristic

inferred from page(s)

published in

Chemical Communications

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28 November 2017

volume

49

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28 November 2017

issue

39

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28 November 2017

page(s)

4148-4150

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Alternate aggregation pathways of the Alzheimer beta-amyloid peptide: Abeta association kinetics at endosomal pH.

28 November 2017

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Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo

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Curcumin labels amyloid pathology in vivo, disrupts existing plaques, and partially restores distorted neurites in an Alzheimer mouse model.

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Identification of amyloid plaques in retinas from Alzheimer's patients and noninvasive in vivo optical imaging of retinal plaques in a mouse model

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Uncharged thioflavin-T derivatives bind to amyloid-beta protein with high affinity and readily enter the brain

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In vivo detection of amyloid plaques in a mouse model of Alzheimer's disease

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Efficient radiosynthesis of carbon-11 labelled uncharged Thioflavin T derivatives using [11C]methyl triflate for beta-amyloid imaging in Alzheimer's Disease with PET.

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Synthesis and evaluation of novel chalcone derivatives with (99m)Tc/Re complexes as potential probes for detection of β-amyloid plaques

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Novel quinoxaline derivatives for in vivo imaging of β-amyloid plaques in the brain.

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Imaging amyloid plaque in Alzheimer's disease brain with a biotinylated Aβ peptide radiopharmaceutical conjugated to an IgG-avidin fusion protein

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Molecular imaging: challenges of bringing imaging of intracellular targets into common clinical use.

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Detection of neuritic plaques in Alzheimer's disease by magnetic resonance microscopy

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In vivo measurement of plaque burden in a mouse model of Alzheimer's disease

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Design and chemical synthesis of a magnetic resonance contrast agent with enhanced in vitro binding, high blood-brain barrier permeability, and in vivo targeting to Alzheimer's disease amyloid plaques.

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21 January 2018

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Detection of Aβ plaques by a novel specific MRI probe precursor CR-BSA-(Gd-DTPA)n in APP/PS1 transgenic mice

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19F and 1H MRI detection of amyloid beta plaques in vivo

21 January 2018

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Fluoro-substituted and 13C-labeled styrylbenzene derivatives for detecting brain amyloid plaques

21 January 2018

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Trifluoromethoxy-benzylated ligands improve amyloid detection in the brain using (19)F magnetic resonance imaging

21 January 2018

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Newly synthesized curcumin derivatives: crosstalk between chemico-physical properties and biological activity.

21 January 2018

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“Clicked” Bivalent Ligands Containing Curcumin and Cholesterol As Multifunctional Aβ Oligomerization Inhibitors: Design, Synthesis, and Biological Characterization

21 January 2018

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Synthesis and identification of new 4-arylidene curcumin analogues as potential anticancer agents targeting nuclear factor-κB signaling pathway

21 January 2018

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21 January 2018

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21 January 2018

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21 January 2018

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Antitumor effects of curcumin and structurally beta-diketone modified analogs on multidrug resistant cancer cells.

21 January 2018

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Curcuminoid analogs with potent activity against Trypanosoma and Leishmania species

21 January 2018

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Novel curcumin analogs targeting TNF-induced NF-kappaB activation and proliferation in human leukemic KBM-5 cells

21 January 2018

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Synthesis of monofunctional curcumin derivatives, clicked curcumin dimer, and a PAMAM dendrimer curcumin conjugate for therapeutic applications.

21 January 2018

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Synthesis, antibacterial and antiviral properties of curcumin bioconjugates bearing dipeptide, fatty acids and folic acid

21 January 2018

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Macromolecules, dendrimers, and nanomaterials in magnetic resonance imaging: the interplay between size, function, and pharmacokinetics

21 January 2018

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Interaction between A beta(1-42) and A beta(1-40) in Alzheimer's beta-amyloid fibril formation in vitro.

21 January 2018

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Interaction of Biphenyl-Functionalized Eu(2+)-Containing Cryptate with Albumin: Implications to Contrast Agents in Magnetic Resonance Imaging

21 January 2018

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The interaction of MS-325 with human serum albumin and its effect on proton relaxation rates

21 January 2018

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The thioflavin T fluorescence assay for amyloid fibril detection can be biased by the presence of exogenous compounds

21 January 2018

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21 January 2018

Identifiers

DOI

10.1039/C2CC36583A

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28 November 2017

1 reference