(Q43932246)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15574416%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

title

Trimeric membrane-anchored gp41 inhibits HIV membrane fusion (English)

1 reference

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5 January 2020

4

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5 January 2020

Karola Vorauer-Uhl

5

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5 January 2020

author name string

Oliver Lenz

1

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5 January 2020

Matthias T Dittmar

2

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5 January 2020

Andreas Wagner

3

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5 January 2020

Gabriela Stiegler

6

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5 January 2020

Winfried Weissenhorn

7

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5 January 2020

language of work or name

English

0 references

publication date

1 December 2004

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15574416%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

5 January 2020

published in

1 reference

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5 January 2020

volume

280

1 reference

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5 January 2020

issue

6

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5 January 2020

page(s)

4095-4101

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15574416%20AND%20SRC:MED&resulttype=core&format=json

The HIV-1 Envelope Glycoproteins: Fusogens, Antigens, and Immunogens

5 January 2020

cites work

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Structural basis for membrane fusion by enveloped viruses

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Mechanisms of viral membrane fusion and its inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Atomic structure of the ectodomain from HIV-1 gp41

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

HIV entry and its inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Core structure of gp41 from the HIV envelope glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Atomic structure of a thermostable subdomain of HIV-1 gp41

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Three-dimensional solution structure of the 44 kDa ectodomain of SIV gp41

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

A synthetic peptide inhibitor of human immunodeficiency virus replication: correlation between solution structure and viral inhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Peptides corresponding to a predictive alpha-helical domain of human immunodeficiency virus type 1 gp41 are potent inhibitors of virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Capture of an early fusion-active conformation of HIV-1 gp41

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Dilation of the human immunodeficiency virus-1 envelope glycoprotein fusion pore revealed by the inhibitory action of a synthetic peptide from gp41

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Evidence that a prominent cavity in the coiled coil of HIV type 1 gp41 is an attractive drug target

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Direct evidence that C-peptide inhibitors of human immunodeficiency virus type 1 entry bind to the gp41 N-helical domain in receptor-activated viral envelope

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Inhibition of HIV-1 entry before gp41 folds into its fusion-active conformation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Design of potent inhibitors of HIV-1 entry from the gp41 N-peptide region

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Enfuvirtide: the first therapy to inhibit the entry of HIV-1 into host CD4 lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Relative replicative fitness of human immunodeficiency virus type 1 mutants resistant to enfuvirtide (T-20).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Sensitivity of human immunodeficiency virus type 1 to the fusion inhibitor T-20 is modulated by coreceptor specificity defined by the V3 loop of gp120

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Sensitivity of human immunodeficiency virus type 1 to fusion inhibitors targeted to the gp41 first heptad repeat involves distinct regions of gp41 and is consistently modulated by gp120 interactions with the coreceptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Sensitivity of HIV-1 to entry inhibitors correlates with envelope/coreceptor affinity, receptor density, and fusion kinetics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

HIV-1 envelope proteins complete their folding into six-helix bundles immediately after fusion pore formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Evidence that the transition of HIV-1 gp41 into a six-helix bundle, not the bundle configuration, induces membrane fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Peptides corresponding to the heptad repeat motifs in the transmembrane protein (gp41) of human immunodeficiency virus type 1 elicit antibodies to receptor-activated conformations of the envelope glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Dissection of human immunodeficiency virus type 1 entry with neutralizing antibodies to gp41 fusion intermediates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Fine definition of the epitope on the gp41 glycoprotein of human immunodeficiency virus type 1 for the neutralizing monoclonal antibody 2F5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

A potent cross-clade neutralizing human monoclonal antibody against a novel epitope on gp41 of human immunodeficiency virus type 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Broadly neutralizing antibodies targeted to the membrane-proximal external region of human immunodeficiency virus type 1 glycoprotein gp41.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

The long third complementarity-determining region of the heavy chain is important in the activity of the broadly neutralizing anti-human immunodeficiency virus type 1 antibody 2F5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Human neutralizing monoclonal antibodies of the IgG1 subtype protect against mucosal simian-human immunodeficiency virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Antiviral activity of the neutralizing antibodies 2F5 and 2G12 in asymptomatic HIV-1-infected humans: a phase I evaluation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Structure and mechanistic analysis of the anti-human immunodeficiency virus type 1 antibody 2F5 in complex with its gp41 epitope

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Structural analysis of the epitope of the anti-HIV antibody 2F5 sheds light into its mechanism of neutralization and HIV fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Antigenicity and immunogenicity of the HIV-1 gp41 epitope ELDKWA inserted into permissive sites of the MalE protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Immunogenic presentation of a conserved gp41 epitope of human immunodeficiency virus type 1 on recombinant surface antigen of hepatitis B virus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Antigenic properties of the human immunodeficiency virus transmembrane glycoprotein during cell-cell fusion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Recognition by human monoclonal antibodies of free and complexed peptides representing the prefusogenic and fusogenic forms of human immunodeficiency virus type 1 gp41

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Binding of the 2F5 monoclonal antibody to native and fusion-intermediate forms of human immunodeficiency virus type 1 gp41: implications for fusion-inducing conformational changes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Genetic evidence that interhelical packing interactions in the gp41 core are critical for transition of the human immunodeficiency virus type 1 envelope glycoprotein to the fusion-active state

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Membrane association induces a conformational change in the Ebola virus matrix protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Enhanced protein loading into liposomes by the multiple crossflow injection technique

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

The crossflow injection technique: an improvement of the ethanol injection method

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Emergence of resistant human immunodeficiency virus type 1 in patients receiving fusion inhibitor (T-20) monotherapy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Trimeric Subdomain of the Simian Immunodeficiency Virus Envelope Glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Oligomeric structure of the human immunodeficiency virus type 1 envelope protein on the virion surface

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Oligomeric structure of virion-associated and soluble forms of the simian immunodeficiency virus envelope protein in the prefusion activated conformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

A trimeric structural domain of the HIV-1 transmembrane glycoprotein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Antigenic implications of human immunodeficiency virus type 1 envelope quaternary structure: oligomer-specific and -sensitive monoclonal antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Modifications that stabilize human immunodeficiency virus envelope glycoprotein trimers in solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Oligomeric and conformational properties of a proteolytically mature, disulfide-stabilized human immunodeficiency virus type 1 gp140 envelope glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Expression, purification, and characterization of gp160e, the soluble, trimeric ectodomain of the simian immunodeficiency virus envelope glycoprotein, gp160.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Expression, purification, and characterization of recombinant HIV gp140. The gp41 ectodomain of HIV or simian immunodeficiency virus is sufficient to maintain the retroviral envelope glycoprotein as a trimer

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Highly stable trimers formed by human immunodeficiency virus type 1 envelope glycoproteins fused with the trimeric motif of T4 bacteriophage fibritin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Stabilization of the soluble, cleaved, trimeric form of the envelope glycoprotein complex of human immunodeficiency virus type 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

A chimeric protein of simian immunodeficiency virus envelope glycoprotein gp140 and Escherichia coli aspartate transcarbamoylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Promoting trimerization of soluble human immunodeficiency virus type 1 (HIV-1) Env through the use of HIV-1/simian immunodeficiency virus chimeras

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Secondary structure, orientation, oligomerization, and lipid interactions of the transmembrane domain of influenza hemagglutinin

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

HIV vaccine design and the neutralizing antibody problem

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Epitope exposure on functional, oligomeric HIV-1 gp41 molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Human immunodeficiency virus type 1-neutralizing monoclonal antibody 2F5 is multispecific for sequences flanking the DKW core epitope

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Enhancement of alpha -helicity in the HIV-1 inhibitory peptide DP178 leads to an increased affinity for human monoclonal antibody 2F5 but does not elicit neutralizing responses in vitro. Implications for vaccine design

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

The membrane-proximal tryptophan-rich region of the HIV glycoprotein, gp41, forms a well-defined helix in dodecylphosphocholine micelles

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Protein design of an HIV-1 entry inhibitor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Design and properties of N(CCG)-gp41, a chimeric gp41 molecule with nanomolar HIV fusion inhibitory activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Covalent trimers of the internal N-terminal trimeric coiled-coil of gp41 and antibodies directed against them are potent inhibitors of HIV envelope-mediated cell fusion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Peptides trap the human immunodeficiency virus type 1 envelope glycoprotein fusion intermediate at two sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Membrane-anchored peptide inhibits human immunodeficiency virus entry

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Inhibition of human immunodeficiency virus type 1 entry in cells expressing gp41-derived peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Synchronized activation and refolding of influenza hemagglutinin in multimeric fusion machines

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Influenza hemagglutinins outside of the contact zone are necessary for fusion pore expansion

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Protein-Lipid Interplay in Fusion and Fission of Biological Membranes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

Prevention of vaginal SHIV transmission in rhesus macaques through inhibition of CCR5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M411088200

21 January 2018

Identifiers

DOI

10.1074/JBC.M411088200

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15574416%20AND%20SRC:MED&resulttype=core&format=json

5 January 2020

1 reference