(Q43962738)

28 November 2017

title

Aggregation of alpha-synuclein induced by the Cu,Zn-superoxide dismutase and hydrogen peroxide system (English)

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28 November 2017

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Kyung Sik Kim

1

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28 November 2017

Soo Young Choi

2

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28 November 2017

Hyeok Yil Kwon

3

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28 November 2017

Moo Ho Won

4

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28 November 2017

Tae Cheon Kang

5

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28 November 2017

Jung Hoon Kang

6

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28 November 2017

publication date

1 March 2002

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Free Radical Biology and Medicine

28 November 2017

published in

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28 November 2017

volume

32

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28 November 2017

issue

6

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28 November 2017

page(s)

544-550

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Alpha-synuclein in Lewy bodies

28 November 2017

cites work

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NACP, a presynaptic protein, immunoreactivity in Lewy bodies in Parkinson's disease.

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Nigral and cortical Lewy bodies and dystrophic nigral neurites in Parkinson's disease and cortical Lewy body disease contain alpha-synuclein immunoreactivity.

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alpha-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with lewy bodies

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Filamentous nerve cell inclusions in neurodegenerative diseases

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7 January 2021

NACP, the precursor protein of the non-amyloid beta/A4 protein (A beta) component of Alzheimer disease amyloid, binds A beta and stimulates A beta aggregation

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7 January 2021

Binding of Abeta to alpha- and beta-synucleins: identification of segments in alpha-synuclein/NAC precursor that bind Abeta and NAC

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7 January 2021

Self-oligomerization of NACP, the precursor protein of the non-amyloid beta/A4 protein (A beta) component of Alzheimer's disease amyloid, observed in the presence of a C-terminal A beta fragment (residues 25-35).

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7 January 2021

Aluminum-induced structural alterations of the precursor of the non-A beta component of Alzheimer's disease amyloid

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7 January 2021

Stabilization of alpha-synuclein secondary structure upon binding to synthetic membranes

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7 January 2021

Oxidative stress induces amyloid-like aggregate formation of NACP/alpha-synuclein in vitro

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7 January 2021

Copper(II)-induced self-oligomerization of alpha-synuclein.

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7 January 2021

Metal-catalyzed oxidation of alpha-synuclein in the presence of Copper(II) and hydrogen peroxide.

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7 January 2021

Impaired neurotransmitter uptake in PC12 cells overexpressing human Cu/Zn-superoxide dismutase--implication for gene dosage effects in Down syndrome

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7 January 2021

Neuronal-specific expression of human copper-zinc superoxide dismutase gene in transgenic mice: animal model of gene dosage effects in Down's syndrome

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7 January 2021

The amyloid precursor protein of Alzheimer's disease in the reduction of copper(II) to copper(I)

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7 January 2021

A gain-of-function of an amyotrophic lateral sclerosis-associated Cu,Zn-superoxide dismutase mutant: An enhancement of free radical formation due to a decrease in Km for hydrogen peroxide

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7 January 2021

A familial amyotrophic lateral sclerosis-associated A4V Cu, Zn-superoxide dismutase mutant has a lower Km for hydrogen peroxide. Correlation between clinical severity and the Km value.

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7 January 2021

Identification of two distinct synucleins from human brain

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7 January 2021

Carbonyl assays for determination of oxidatively modified proteins.

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7 January 2021

Antioxidant activity of carnosine, homocarnosine, and anserine present in muscle and brain

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7 January 2021

Detection, characterisation, and quantification of carnosine and other histidyl derivatives in cardiac and skeletal muscle

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7 January 2021

Muscle buffering capacity and dipeptide content in the thoroughbred horse, greyhound dog and man.

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7 January 2021

The effects of carnosine and anserine on glycolytic reactions in skeletal muscle

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7 January 2021

Interactions among carnosine, anserine, ophidine and copper in biochemical adaptation

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7 January 2021

Is Parkinson's disease a progressive siderosis of substantia nigra resulting in iron and melanin induced neurodegeneration?

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7 January 2021

Oxidative stress and the pathogenesis of Parkinson's disease

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7 January 2021

Oxidative alterations in Alzheimer's disease

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7 January 2021

Raised cerebrospinal-fluid copper concentration in Parkinson's disease

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7 January 2021

Hydrogen peroxide-mediated Cu,Zn-superoxide dismutase fragmentation: protection by carnosine, homocarnosine and anserine.

1 reference

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7 January 2021

Cu/Zn superoxide dismutase-like immunoreactivity is present in Lewy bodies from Parkinson disease: a light and electron microscopic immunocytochemical study

1 reference

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7 January 2021

Lewy bodies are ubiquitinated. A light and electron microscopic immunocytochemical study

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7 January 2021

Alpha synuclein in neurodegenerative disorders: murderer or accomplice?

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7 January 2021

Toxic DNA damage by hydrogen peroxide through the Fenton reaction in vivo and in vitro

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7 January 2021

Ferritin and haemosiderin in free radical generation, lipid peroxidation and protein damage

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7 January 2021

10.1016/S0891-5849(02)00741-4

Identifiers

DOI

1 reference

28 November 2017

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