(Q43985366)

28 November 2017

General pharmacokinetic model for drugs exhibiting target-mediated drug disposition (English)

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28 November 2017

1 reference

D E Mager

1

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PubMed ID

11999290

28 November 2017

W J Jusko

series ordinal

2

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28 November 2017

1 December 2001

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Journal of Pharmacokinetics and Pharmacodynamics

28 November 2017

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28 November 2017

28

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28 November 2017

507-532

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28 November 2017

6

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https://scigraph.springernature.com/pub.10.1023/a:1014414520282

28 November 2017

0 references

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Comparative pharmacokinetics and pharmacodynamics of two recombinant human interferon beta-1a (IFN beta-1 a) products administered intramuscularly in healthy male and female volunteers

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12 December 2020

Transit compartments versus gamma distribution function to model signal transduction processes in pharmacodynamics

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12 December 2020

Endothelin receptor antagonists: current status and perspectives

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12 December 2020

Phase I study of recombinant tumor necrosis factor in cancer patients.

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12 December 2020

Effect of saturable binding on the pharmacokinetics of drugs: a simulation

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12 December 2020

Studies with low dose intravenous diacid ACE inhibitor (perindoprilat) infusions in normotensive male volunteers

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12 December 2020

Mean residence time concepts for pharmacokinetic systems with nonlinear drug elimination described by the Michaelis-Menten equation.

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12 December 2020

Pharmacokinetics and pharmacodynamics of recombinant human interferon-beta in healthy male volunteers

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12 December 2020

Multiple-dose pharmacokinetics, safety, and tolerability of bosentan, an endothelin receptor antagonist, in healthy male volunteers

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12 December 2020

Pharmacokinetics of an ACE inhibitor, S-9780, in man: evidence of tissue binding

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12 December 2020

Intracellular pathways and mechanisms of sorting in receptor-mediated endocytosis

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12 December 2020

Precursor-dependent indirect pharmacodynamic response model for tolerance and rebound phenomena

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12 December 2020

Pharmacokinetics of capacity-limited tissue distribution of methicillin in rabbits.

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12 December 2020

Pharmacologic target-mediated drug disposition

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12 December 2020

Recycling receptors: The round-trip itinerary of migrant membrane proteins

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12 December 2020

Dose-dependent pharmacokinetics: experimental observations and theoretical considerations

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12 December 2020

Pharmacokinetics and pharmacodynamics of IFN-beta 1a in healthy volunteers

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12 December 2020

Pharmacodynamic modeling of time-dependent transduction systems

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12 December 2020

Saturable tissue binding and imirestat pharmacokinetics in rats

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12 December 2020

Comparison of four basic models of indirect pharmacodynamic responses

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12 December 2020

A combined specific target site binding and pharmacokinetic model to explore the non-linear disposition of draflazine

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12 December 2020

Pharmacological characterization of bosentan, a new potent orally active nonpeptide endothelin receptor antagonist

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12 December 2020

Operational models of pharmacological agonism.

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12 December 2020

Protein sorting by transport vesicles

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12 December 2020

Nonlinear pharmacokinetics and metabolism of paclitaxel and its pharmacokinetic/pharmacodynamic relationships in humans

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12 December 2020

Clinical Pharmacokinetics of Interferons

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12 December 2020

Pharmacokinetics of repeated single oral doses of enalapril maleate (mk-421) in normal volunteers

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12 December 2020

Pharmacokinetics of recombinant human interferon-beta ser in healthy volunteers and its effect on serum neopterin

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12 December 2020

Interferons and their actions

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12 December 2020

Receptor-mediated transport of peptide hormones and its importance in the overall hormone disposition in the body

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12 December 2020

Single pass mean residence time in peripheral tissues: a distribution parameter intrinsic to the tissue affinity of a drug

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12 December 2020

Dose-dependent pharmacokinetics of the aldose reductase inhibitor imirestat in man

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12 December 2020

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12 December 2020

Pharmacokinetics and pharmacodynamics of the endothelin-receptor antagonist bosentan in healthy human subjects.

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12 December 2020

Absorption, excretion, and metabolism of the endothelin receptor antagonist bosentan in healthy male subjects

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12 December 2020

Identifiers

DOI

10.1023/A:1014414520282

1 reference

PubMed ID

11999290

Dimensions Publication ID

28 November 2017

0 references

1 reference

PubMed ID

11999290