(Q43986703)

28 November 2017

Structural features underlying selective inhibition of GSK3β by dibromocantharelline: implications for rational drug design (English)

1 reference

28 November 2017

Na Zhang

1

1 reference

28 November 2017

Rugang Zhong

series ordinal

2

1 reference

28 November 2017

Hong Yan

series ordinal

3

1 reference

28 November 2017

Yongjun Jiang

series ordinal

4

1 reference

28 November 2017

19 January 2011

1 reference

Chemical Biology and Drug Design

28 November 2017

1 reference

28 November 2017

77

1 reference

28 November 2017

3

1 reference

28 November 2017

199-205

1 reference

Signal perception and transduction: the role of protein kinases

28 November 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

The regulation of protein function by multisite phosphorylation--a 25 year update

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

Signaling--2000 and beyond

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

Protein kinase inhibitors: insights into drug design from structure.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

Strategies toward the design of novel and selective protein tyrosine kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

Glycogen synthase kinase-3: properties, functions, and regulation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

21 January 2018

The renaissance of GSK3

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

GSK-3: tricks of the trade for a multi-tasking kinase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

GSK-3 inhibitors: discoveries and developments

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

Pharmacological inhibitors of glycogen synthase kinase 3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

Clinical status of anti-cancer agents derived from marine sources

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

Natural-product diversity of the New Caledonian marine ecosystem compared to other ecosystems: a pharmacologically oriented view

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

Inhibition of cyclin-dependent kinases, GSK-3beta and CK1 by hymenialdisine, a marine sponge constituent

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

Synthesis and target identification of hymenialdisine analogs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

Aldisine alkaloids from the Philippine sponge Stylissa massa are potent inhibitors of mitogen-activated protein kinase kinase-1 (MEK-1).

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

Combining docking and molecular dynamic simulations in drug design

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

Molecular dynamics simulations of biomolecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

Strategies for the design of potent and selective kinase inhibitors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

Structure-based approaches to improve selectivity: CDK2-GSK3beta binding site analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

Implications of protein flexibility for drug discovery

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

Protein flexibility is an important component of structure-based drug discovery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

Protein flexibility in ligand docking and virtual screening to protein kinases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

Structure and regulation of the CDK5-p25(nck5a) complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

Crystal structure of glycogen synthase kinase 3 beta: structural basis for phosphate-primed substrate specificity and autoinhibition

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

Mechanism of CDK5/p25 binding by CDK inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

Different mechanisms of CDK5 and CDK2 activation as revealed by CDK5/p25 and CDK2/cyclin A dynamics

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

Comparative study of several algorithms for flexible ligand docking

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

Evaluation of docking performance: comparative data on docking algorithms

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

A fast flexible docking method using an incremental construction algorithm.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

Development and validation of a genetic algorithm for flexible docking

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

A Second Generation Force Field for the Simulation of Proteins, Nucleic Acids, and Organic Molecules

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

A point-charge force field for molecular mechanics simulations of proteins based on condensed-phase quantum mechanical calculations

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

Comparison of simple potential functions for simulating liquid water

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

Numerical integration of the cartesian equations of motion of a system with constraints: molecular dynamics of n-alkanes

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

Fragment and knowledge-based design of selective GSK-3beta inhibitors using virtual screening models.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

Thienylhalomethylketones: Irreversible glycogen synthase kinase 3 inhibitors as useful pharmacological tools.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

The synthesis of peptidylfluoromethanes and their properties as inhibitors of serine proteinases and cysteine proteinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

Binding of chloromethyl ketone substrate analogues to crystalline papain

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

N-tosyl-L-phenylalanine chloromethyl ketone inhibits NF-kappaB activation by blocking specific cysteine residues of IkappaB kinase beta and p65/RelA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

Inactivation of NF-kappaB components by covalent binding of (-)-dehydroxymethylepoxyquinomicin to specific cysteine residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

Particle mesh Ewald: An N⋅log(N) method for Ewald sums in large systems

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

Differential Binding of Inhibitors to Active and Inactive CDK2 Provides Insights for Drug Design

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1747-0285.2010.01069.X

10.1111/J.1747-0285.2010.01069.X

21 January 2018

Identifiers

DOI

1 reference

28 November 2017

1 reference