(Q43990167)

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Inhibition of plasmodium falciparum triose-phosphate isomerase by chemical modification of an interface cysteine. Electrospray ionization mass spectrometric analysis of differential cysteine reactivities

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Europe PubMed Central

PubMed publication ID

28 November 2017

Inhibition of plasmodium falciparum triose-phosphate isomerase by chemical modification of an interface cysteine. Electrospray ionization mass spectrometric analysis of differential cysteine reactivities (English)

1 reference

Europe PubMed Central

PubMed publication ID

28 November 2017

Plasmodium falciparum

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electrospray ionization

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author name string

Kapil Maithal

1

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Europe PubMed Central

PubMed publication ID

28 November 2017

Gudihal Ravindra

2

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Europe PubMed Central

PubMed publication ID

28 November 2017

Hemalatha Balaram

3

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Europe PubMed Central

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28 November 2017

Padmanabhan Balaram

4

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Europe PubMed Central

PubMed publication ID

28 November 2017

language of work or name

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publication date

2 May 2002

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28 November 2017

Journal of Biological Chemistry

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Europe PubMed Central

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28 November 2017

277

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Europe PubMed Central

PubMed publication ID

28 November 2017

28

1 reference

Europe PubMed Central

PubMed publication ID

28 November 2017

25106-25114

1 reference

Europe PubMed Central

PubMed publication ID

28 November 2017

A potential target enzyme for trypanocidal drugs revealed by the crystal structure of NAD-dependent glycerol-3-phosphate dehydrogenase from Leishmania mexicana

1 reference

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21 January 2018

A 2.8 A resolution structure of 6-phosphogluconate dehydrogenase from the protozoan parasite Trypanosoma brucei: comparison with the sheep enzyme accounts for differences in activity with coenzyme and substrate analogues

1 reference

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21 January 2018

Rational design of novel antimicrobials: blocking purine salvage in a parasitic protozoan

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Tritrichomonas foetus: a strategy for structure-based inhibitor design of a protozoan inosine-5'-monophosphate dehydrogenase

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21 January 2018

Transition-state analogs as inhibitors of human and malarial hypoxanthine-guanine phosphoribosyltransferases

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21 January 2018

Metabolism and functions of trypanothione in the Kinetoplastida

1 reference

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21 January 2018

Protein crystallography and infectious diseases

1 reference

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21 January 2018

Synthetic "interface" peptides alter dimeric assembly of the HIV 1 and 2 proteases

1 reference

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21 January 2018

Structure-based discovery of inhibitors of thymidylate synthase

1 reference

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21 January 2018

Inhibition of triosephosphate isomerase from Trypanosoma brucei with cyclic hexapeptides.

1 reference

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21 January 2018

Simple alkanethiol groups for temporary blocking of sulfhydryl groups of enzymes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202419200

21 January 2018

Active center studies on bacterial luciferase: modification of the enzyme with 2,4-dinitrofluorobenzene.

1 reference

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21 January 2018

Species-specific inhibition of homologous enzymes by modification of nonconserved amino acids residues. The cysteine residues of triosephosphate isomerase

1 reference

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21 January 2018

Compartmentation of carbohydrate metabolism in trypanosomes

1 reference

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21 January 2018

Localization of nine glycolytic enzymes in a microbody-like organelle in Trypanosoma brucei : The glycosome

1 reference

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21 January 2018

Inhibition of glyceraldehyde-3-phosphate dehydrogenase by phosphorylated epoxides and alpha-enones.

1 reference

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21 January 2018

Enzyme catalysis: not different, just better

1 reference

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21 January 2018

Kinetic properties of triose-phosphate isomerase from Trypanosoma brucei brucei. A comparison with the rabbit muscle and yeast enzymes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202419200

21 January 2018

Tiny TIM: a small, tetrameric, hyperthermostable triosephosphate isomerase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202419200

21 January 2018

Anion binding at the active site of trypanosomal triosephosphate isomerase. Monohydrogen phosphate does not mimic sulphate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202419200

21 January 2018

Refolding of triose phosphate isomerase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202419200

21 January 2018

A double mutation at the tip of the dimer interface loop of triosephosphate isomerase generates active monomers with reduced stability.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202419200

21 January 2018

Three hTIM mutants that provide new insights on why TIM is a dimer

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202419200

21 January 2018

The ionization of a buried glutamic acid is thermodynamically linked to the stability of Leishmania mexicana triose phosphate isomerase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202419200

21 January 2018

Cavity-creating mutation at the dimer interface of Plasmodium falciparum triosephosphate isomerase: restoration of stability by disulfide cross-linking of subunits.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202419200

21 January 2018

Segmental movement: definition of the structural requirements for loop closure in catalysis by triosephosphate isomerase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202419200

21 January 2018

Triosephosphate isomerase requires a positively charged active site: the role of lysine-12

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202419200

21 January 2018

Differences in the intersubunit contacts in triosephosphate isomerase from two closely related pathogenic trypanosomes

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202419200

21 January 2018

Triosephosphate isomerase from Plasmodium falciparum: the crystal structure provides insights into antimalarial drug design

1 reference

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21 January 2018

Triose-phosphate isomerase of Leishmania mexicana mexicana. Cloning and characterization of the gene, overexpression in Escherichia coli and analysis of the protein

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202419200

21 January 2018

Sulfhydryl reagent susceptibility in proteins with high sequence similarity--triosephosphate isomerase from Trypanosoma brucei, Trypanosoma cruzi and Leishmania mexicana

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202419200

21 January 2018

Cloning of the triosephosphate isomerase gene of Plasmodium falciparum and expression in Escherichia coli

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202419200

21 January 2018

pH-dependence of the triose phosphate isomerase reaction

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202419200

21 January 2018

Factors that control the reactivity of the interface cysteine of triosephosphate isomerase from Trypanosoma brucei and Trypanosoma cruzi.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202419200

21 January 2018

Kinetics and energetics of subunit dissociation/unfolding of TIM: the importance of oligomerization for conformational persistence and chemical stability of proteins.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202419200

21 January 2018

Comparison of the refined crystal structures of liganded and unliganded chicken, yeast and trypanosomal triosephosphate isomerase

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202419200

21 January 2018

The nature of the accessible and buried surfaces in proteins

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202419200

21 January 2018

Refined 1.83 Å structure of trypanosomal triosephosphate isomerase crystallized in the presence of 2.4 m-ammonium sulphate

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202419200

21 January 2018

Derivatization of the Interface Cysteine of Triosephosphate Isomerase fromTrypanosoma bruceiandTrypanosoma cruzias Probe of the Interrelationship between the Catalytic Sites and the Dimer Interface†

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M202419200

21 January 2018

Identifiers

10.1074/JBC.M202419200

1 reference

Europe PubMed Central

PubMed publication ID

28 November 2017

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

28 November 2017

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