(Q44004456)

28 November 2017

title

Embryonic arrhythmia by inhibition of HERG channels: a common hypoxia-related teratogenic mechanism for antiepileptic drugs? (English)

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28 November 2017

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Faranak Azarbayjani

1

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28 November 2017

Bengt R Danielsson

series ordinal

2

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28 November 2017

publication date

1 May 2002

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28 November 2017

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28 November 2017

volume

43

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28 November 2017

issue

5

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28 November 2017

page(s)

457-468

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Parental epilepsy, anticonvulsant drugs, and reproductive outcome: epidemiologic and experimental findings spanning three decades; 1: Animal studies

28 November 2017

cites work

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

Class III antiarrhythmics and phenytoin: teratogenicity due to embryonic cardiac dysrhythmia and reoxygenation damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

Inhibition of delayed rectifier K+ channels by phenytoin in rat neuroblastoma cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

A family of potassium channel genes related to eag in Drosophila and mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

Developmental changes in ionic channel activity in the embryonic murine heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

Teratogenic potential of almokalant, dofetilide, and d-sotalol: drugs with potassium channel blocking activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

Long QT syndromes and torsade de pointes

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

Drug-induced cardiac arrhythmias: incidence, prevention and management

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

Arrhythmia, heart rate variability, and antiepileptic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

Uptake, distribution, metabolism, and excretion of trimethadione in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

Inhibition of trimethadione and dimethadione teratogenicity by the cyclooxygenase inhibitor acetylsalicylic acid: a unifying hypothesis for the teratologic effects of hydantoin anticonvulsants and structurally related compounds

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

Dimethadione-induced fetotoxicity in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

Teratogenicity of the class III antiarrhythmic drug almokalant. Role of hypoxia and reactive oxygen species

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

HPLC procedure for the pharmacokinetic study of the spin-trapping agent, alpha-phenyl-N-tert-butyl nitrone (PBN).

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

Pharmacologically induced embryonic dysrhythmia and episodes of hypoxia followed by reoxygenation: a common teratogenic mechanism for antiepileptic drugs?

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

Phenytoin-induced cleft palate: evidence for embryonic cardiac bradyarrhythmia due to inhibition of delayed rectifier K+ channels resulting in hypoxia-reoxygenation damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

Rapid and simple HPLC determination of 5,5-dimethyl-2,4-oxazolidynedione in rabbit serum

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

Fetal anomalies following maternal trimethadione ingestion

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

The fetal trimethadione syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

The Fetal Trimethadione Syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

Anticonvulsants During Pregnancy: A Danger to the Developing Fetus?

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

Teratogen update: fetal hydantoin effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

DPH-induced macrocytosis in the 14-day rat foetus

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

Histopathological and hemodynamic studies supporting hypoxia and vascular disruption as explanation to phenytoin teratogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

Free radicals in disease processes: a compilation of cause and consequence

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

Human disease, free radicals, and the oxidant/antioxidant balance

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

Reactive oxygen species and DNA oxidation in fetal rat tissues.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

Embryotoxic effects of L-691,121, a class III antiarrhythmic agent, in rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

Uterine trauma and limb defects.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

Phenytoin causes phalangeal hypoplasia in the rabbit fetus at clinically relevant free plasma concentrations

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

Identical phalangeal defects induced by phenytoin and nifedipine suggest fetal hypoxia and vascular disruption behind phenytoin teratogenicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

Induction of postaxial forelimb ectrodactyly with anticonvulsant agents in A/J mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

The effect of administration time on malformations induced by three anticonvulsant agents in C57BL/6J mice with emphasis on forelimb ectrodactyly

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

Folate antagonism following teratogenic exposure to diphenylhydantoin

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

Stage-specific skeletal and visceral defects of the I(Kr)-blocker almokalant: further evidence for teratogenicity via a hypoxia-related mechanism.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

Comparative teratogenicity of phenytoin among several inbred strains of mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

Ischemia/reperfusion: a new hypothesis for the developmental toxicity of cocaine

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

Studies of the role of ischemia/reperfusion and superoxide anion radical production in the teratogenicity of cocaine

21 January 2018

1 reference

https://api.crossref.org/works/10.1046%2FJ.1528-1157.2002.28999.X

10.1046/J.1528-1157.2002.28999.X

21 January 2018

Identifiers

DOI

1 reference

28 November 2017

1 reference