(Q44005248)

28 November 2017

title

Novel inhibition of porcine pepsin by a substituted piperidine. Preference for one of the enzyme conformers (English)

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28 November 2017

author name string

Jovita Marcinkeviciene

1

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28 November 2017

Lisa M Kopcho

2

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28 November 2017

Tao Yang

3

1 reference

28 November 2017

Robert A Copeland

4

1 reference

28 November 2017

Brian M Glass

5

1 reference

28 November 2017

Andrew P Combs

6

1 reference

28 November 2017

Nikoo Falahatpisheh

7

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28 November 2017

Lorin Thompson

8

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28 November 2017

language of work or name

English

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publication date

23 May 2002

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Journal of Biological Chemistry

28 November 2017

published in

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28 November 2017

volume

277

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28 November 2017

issue

32

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28 November 2017

page(s)

28677-28682

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HIV protease: a novel chemotherapeutic target for AIDS.

28 November 2017

cites work

1 reference

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Secretases as targets for the treatment of Alzheimer's disease

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Hemoglobin metabolism in the malaria parasite Plasmodium falciparum

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Rational design of potent, bioavailable, nonpeptide cyclic ureas as HIV protease inhibitors

21 January 2018

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Potency and selectivity of inhibition of human immunodeficiency virus protease by a small nonpeptide cyclic urea, DMP 323

21 January 2018

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Potent, low-molecular-weight non-peptide inhibitors of malarial aspartyl protease plasmepsin II.

21 January 2018

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New class of small nonpeptidyl compounds blocks Plasmodium falciparum development in vitro by inhibiting plasmepsins

21 January 2018

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Three-dimensional structure of the complex of the Rhizopus chinensis carboxyl proteinase and pepstatin at 2.5-A resolution

21 January 2018

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From peptides to non-peptide peptidomimetics: design and synthesis of new piperidine inhibitors of aspartic peptidases.

21 January 2018

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The rate-determining step in pepsin-catalysed reactions, and evidence against an acyl-enzyme intermediate

21 January 2018

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Structure and refinement of penicillopepsin at 1.8 Å resolution

21 January 2018

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Inhibitor binding to the Phe53Trp mutant of HIV-1 protease promotes conformational changes detectable by spectrofluorometry.

21 January 2018

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Mechanism of Inhibition of beta-site amyloid precursor protein-cleaving enzyme (BACE) by a statine-based peptide

21 January 2018

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Binding of a reduced peptide inhibitor to the aspartic proteinase from Rhizopus chinensis: implications for a mechanism of action

21 January 2018

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Ab initio molecular dynamics-based assignment of the protonation state of pepstatin A/HIV-1 protease cleavage site

21 January 2018

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A neutron Laue diffraction study of endothiapepsin: implications for the aspartic proteinase mechanism

21 January 2018

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Human immunodeficiency virus-1 protease. 2. Use of pH rate studies and solvent kinetic isotope effects to elucidate details of chemical mechanism

21 January 2018

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Construction and evaluation of the kinetic scheme associated with dihydrofolate reductase from Escherichia coli

21 January 2018

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Follow the protons: a low-barrier hydrogen bond unifies the mechanisms of the aspartic proteases

21 January 2018

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Designing non-peptide peptidomimetics in the 21st century: inhibitors targeting conformational ensembles.

21 January 2018

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Maintenance of blood pressure by the renin–angiotensin system in normal man

21 January 2018

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Piperidine-renin inhibitors compounds with improved physicochemical properties

21 January 2018

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Kinetics of the inhibition of human renin by an inhibitor containing a hydroxyethylene dipeptide isostere

21 January 2018

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Renin inhibition by substituted piperidines: a novel paradigm for the inhibition of monomeric aspartic proteinases?

21 January 2018

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Substituted piperidines--highly potent renin inhibitors due to induced fit adaptation of the active site

21 January 2018

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STUDIES ON LIVER ALCOHOL HYDROGENASE COMPLEXES. 3. MULTIPLE INHIBITION KINETICS IN THE PRESENCE OF TWO COMPETITIVE INHIBITORS

21 January 2018

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Ionization states of the catalytic residues in HIV-1 protease

21 January 2018

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Dissection of the pH dependence of inhibitor binding energetics for an aspartic protease: direct measurement of the protonation states of the catalytic aspartic acid residues

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M203120200

21 January 2018

Identifiers

DOI

10.1074/JBC.M203120200

1 reference

release_ltsgwayefrfnbk4ov4nwsmk35e

28 November 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/ltsgwayefrfnbk4ov4nwsmk35e

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference